- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Long-Term Effects of COVID-19
- Electrical and Bioimpedance Tomography
- Superconducting and THz Device Technology
- Osteomyelitis and Bone Disorders Research
- Tracheal and airway disorders
- Physics of Superconductivity and Magnetism
- Dysphagia Assessment and Management
- Bone and Joint Diseases
- Respiratory viral infections research
- Nosocomial Infections in ICU
- Oral Health Pathology and Treatment
- Respiratory and Cough-Related Research
- Influenza Virus Research Studies
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Skin Diseases and Diabetes
Beijing University of Chinese Medicine
2022-2025
Beijing Hospital of Traditional Chinese Medicine
2025
Capital Medical University
2025
First Affiliated Hospital of Guangzhou Medical University
2015-2024
Guangzhou Medical University
2015-2024
State Key Laboratory of Respiratory Disease
2014-2024
Fujian Medical University
2024
Second Affiliated Hospital of Fujian Medical University
2024
The Second Affiliated Hospital of Xiamen Medical College
2022
The 180th Hospital of PLA
2022
Abstract Background and objective Aetiologies of bronchiectasis in mainland C hina their comparisons with those western countries are unknown. We aimed to investigate aetiologies G uangzhou, southern hina, determine ethnic or geographic differences reports from countries. Methods Consecutive patients steady‐state were randomly recruited. Past history was meticulously extracted. Patients underwent physical examination, saccharine test, humoral immunity assays, gastroesophageal reflux scoring...
Background Characteristics of lung function impairment in bronchiectasis is not fully understood. Objectives To determine the factors associated with and to compare changes spirometry during exacerbation convalescence (1 week following 14-day antibiotic therapy). Methods We recruited 142 patients steady-state bronchiectasis, whom 44 acute exacerbations follow-up were included subgroup analyses. Baseline measurements consisted chest high-resolution computed tomography (HRCT), sputum volume,...
Background: Since 2020 COVID-19 pandemic became an emergent public sanitary incident. The epidemiology data and the impact on prognosis of secondary infection in severe critical patients China remained largely unclear. Methods: We retrospectively reviewed medical records all adult with laboratory-confirmed who were admitted to ICUs from January 18th April 26th at two hospitals Wuhan, one hospital Guangzhou, China. measured frequency bacteria fungi cultured respiratory tract, blood other body...
Palmoplantar pustulosis is a chronic recurrent dermatological condition of unknown aetiology, and available clinical experience suggests that symptoms tend to diminish during pregnancy, but we report case 31-year-old woman whose worsened after which prompted us focus on this problem cure her disease with new treatment regimen, tofacitibi.
Palmoplantar pustulosis (PPP) is a chronic inflammatory skin disease with recurrent erythema, scales, and sterile pustules on the palms soles. Treating PPP in children difficult due to limited effective therapies, especially as there's lack of data upadacitinib use under 12.This article reports pediatric case. The patient had severe, recurring rashes that affected daily activities. Treated for two months, she showed significant therapeutic response.
Rationale: The usefulness of impulse oscillometry (IOS) in bronchiectasis has not been systematically investigated.Objectives: To determine the IOS parameters and their correlation with radiology, disease severity, sputum bacteriology, spirometry, to compare changes during exacerbations convalescence bronchiectasis.Methods: We recruited 100 patients 28 healthy subjects. Receiver operating characteristic curve was plotted analyze diagnostic performance parameters. Chest high-resolution...
Abstract Background In December 2019, human infection with a novel coronavirus, known as SARS-CoV-2, was identified in Wuhan, China. The mortality of critical illness high Wuhan. Information about critically ill patients SARS-CoV-2 outside Wuhan is scarce. We aimed to provide the clinical features, treatment, and prognosis Guangdong Province. Methods this multi-centered, retrospective, observational study, we enrolled pneumonia who were admitted intensive care unit (ICU) Demographic data,...
In our manuscript, we present a case study of siblings with Generalized Pustular Psoriasis (GPP) and Acrodermatitis Continua Hallopeau (ACH), both harboring IL36RN gene mutations. The 3-year-old proband exhibited systemic pustules leading to GPP diagnosis, while his 6-year-old sister developed nail ulcers subungual characteristic ACH. Despite standard treatments, their conditions were refractory. Genetic analysis revealed homozygous splice variant c.115+6 T>C, heterozygous parents. This...
<h3>BACKGROUND:</h3> Bronchiectasis exacerbations are critical events characterized by worsened symptoms and signs (ie, cough frequency, sputum volume, malaise). <h3>Objectives:</h3> Our goal was to examine variations in airway systemic inflammation, spirometry, quality of life during steady state, bronchiectasis exacerbations, convalescence (1 week following a 2-week antibiotic treatment) determine whether potentially pathogenic microorganisms, including <i>Pseudomonas aeruginosa</i>, were...
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with coagulation abnormalities which are indicators of higher mortality especially in severe cases. Methods We studied patients proven COVID-19 the intensive care unit Jinyintan Hospital, Wuhan, China from 30 to 31 March 2020. Results Of 180 patients, 89 (49.44 %) had died, 85 (47.22 been discharged alive, and 6 (3.33 were still hospitalised by end data collection. A D-dimer concentration > 0.5 mg/L on admission was...
Background Sleep disturbances are common in patients with chronic lung diseases, but little is known about the prevalence bronchiectasis. A cross sectional study was conducted to investigate and determinants associated sleep disturbances, correlation between quality of life (QoL) adults steady-state Methods One hundred forty-four bronchiectasis eighty healthy subjects were enrolled. daytime sleepiness, QoL measured by utilizing Pittsburgh Quality Index (PSQI), Epworth Sleepiness Scale (ESS)...
Background Cough hypersensitivity has been common among respiratory diseases. Objective To determine associations of capsaicin cough sensitivity and clinical parameters in adults with clinically stable bronchiectasis. Methods We recruited 135 consecutive adult bronchiectasis patients 22 healthy subjects. History inquiry, sputum culture, spirometry, chest high-resolution computed tomography (HRCT), Leicester Questionnaire scoring, Bronchiectasis Severity Index (BSI) assessment inhalation...
Abstract: Noninvasive ventilation with a plateau exhalation valve (PEV) is often used as an adjunct to exercise achieve physiologic training effect in severe chronic obstructive pulmonary disease (COPD) patients. However, during exercise, the increase of flow and respiratory rate limited capability PEV exhale gases out circuit, it still unknown whether CO 2 rebreathing occurs COPD patients ventilated assisted by single-limb circuit PEV. A maximal symptom-limited cycle test was performed...