Staphylococci are a common cause of catheter-associated urinary tract infections. The present study evaluated biofilm forming capacity and the presence both icaA icaD genes among staphylococci strains isolated from patients undergoing ureteral catheterization.Different bacterial were urine stents segments collected 100 patients. Strains identified by traditional microbiological methods. Stents examined for using scanning electron microscope (SEM). Staphylococcal isolates tested their ability...

The emergence of colistin-resistant strains is considered a great threat for patients with severe infections. Here, we investigate the prevalence and some possible mechanisms colistin resistance among multidrug-resistant (MDR) extensively drug-resistant (XDR) Pseudomonas aeruginosa (P. aeruginosa).Antimicrobial susceptibility was performed using disc diffusion methods while detected by agar dilution method. Possible were studied detection mcr-1 mcr-2 genes conventional PCR, efflux Carbonyl...

Silver is a potent antimicrobial agent against variety of microorganisms and once the element has entered bacterial cell, it accumulates as silver nanoparticles with large surface area causing cell death. At same time, becomes reservoir for silver. This study aims to test microcidal effect silver-killed E. coli O104: H4 its supernatant fresh viable cells bacterium some other species, including O157: H7, Multidrug Resistant (MDR) Pseudomonas aeruginosa Methicillin Staphylococcus aureus...

Background:Pseudomonas aeruginosa (P. aeruginosa) represents a great threat to public health worldwide, due its high ability acquire resistance different antibiotic classes. Carbapenems are effective against multidrug resistant (MDR) P. aeruginosa, but their widespread use has resulted in the emergence of carbapenem-resistant strains, which is considered major global concern. This study aimed determine prevalence carbapenem among strains isolated from sites infection. Methods: Between...

Background: The rapid emergence of antimicrobial resistance among Gram-positive organisms, especially staphylococci, has become a serious clinical challenge. Efflux machinery and biofilm formation are considered two the main causes therapy failure. Aim: Our study aims to evaluate antibiofilm efflux pump inhibitory activity antifungal ketoconazole against multidrug-resistant (MDR) Staphylococcus aureus. Methods: Ketoconazole was tested for its effect on following: minimum concentrations...

Escherichia (E.) coli can cause intestinal and extra-intestinal infections which ranged from mild to life-threatening infections. The severity of infection is a product many factors including virulence properties antimicrobial resistance.To determine the antibiotic resistance pattern, distribution their association with one another some selected genes.Virulence were analyzed phenotypically while susceptibility was tested by Kirby-Bauer agar disc diffusion method. In addition, 64 E. isolates...

Antimicrobial resistance and virulence genes play important roles in increasing the severity of Pseudomonas aeruginosa infections, especially hospitalized patients with high antibiotic pressure. Most that encode factors are controlled regulated by quorum sensing (QS) system. The aim this study was to investigate frequency some (rhlR, rhlI, lasR, lasI, lasB, toxA, aprA, algD, ExoS, plcH genes) their association resistance.Antimicrobial susceptibility determined Kirby-Bauer agar disk diffusion...

Abstract Background A major worldwide health issue is the rising frequency of resistance bacteria.Drug combinations are a winning strategy in fighting resistant bacteria and might help protecting existing drugs.Monolaurin natural compound extracted from coconut oil has promising antimicrobial activity against Staphylococcus.aureus . This study aims to examine efficacy monolaurin both individually combination with β-lactam antibiotics Staphylococcus aureus isolates. Methods Agar dilution...

Introduction: The efficacy of several antimicrobial agents has been hindered due to the increasing frequency multidrug-resistant (MDR) Pseudomonas aeruginosa strains. So, need for new antibacterial drugs or drug combinations is urgent. Recently, desirable effects were reported many metals nanoparticles such as TiO 2 (TDNs). Purpose: This study aims investigate prevalence MDR P. and assess efficiency TDN in treatment -associated infections. Materials Methods: synthesis by sol-gel method was...

The emergence of multi-drug resistant (MDR) strains and even pan drug (PDR) is alarming. In this study, we studied the resistance pattern E. coli pathogens recovered from patients with different infections in hospitals Minia, Egypt co-existence determinants. was most prevalent among suffering urinary tract (62%), while they were least isolated eye (10%). High prevalence MDR isolates found (73%) associated high ESBLs MBLs production (89.4% 64.8%, respectively). blaTEM (80%) blaNDM (43%)...

Ureteral catheters are indispensable devices used in the management of ureteral obstruction. Although stent is essential for treatment, it also has complications, which encrustation, stone formation and biofilm formation. Biofilm infections result a complication course increasing length patients stay hospital overall cost. Catheter-associated difficult to be treated with antibiotics there need change due on their surfaces. In this study, we examine effect some prescribed drugs as NSAIDs...

Introduction: Multidrug resistant (MDR) Acinetobacter baumanii (A. baumannii) strains have emerged as novel nosocomial pathogens threatening patients' lives, especially in intensive-care units (ICUs). This study aims to determine the prevalence of carbapenemase genes and CTX-M-15 resistance pattern producing isolates.Methods: A total 530 clinical specimens were collected from patients suffering different infections, antibiotic susceptibility test was performed using kirby-bauer disk...

Most of the infections caused by multi-drug resistant (MDR) P. aeruginosa strains are extremely difficult to be treated with conventional antibiotics. Biofilm formation and efflux pumps recognized as major antibiotic resistance mechanisms in MDR aeruginosa. depends mainly on cell-to-cell communication quorum-sensing (QS) systems. Titanium dioxide nanoparticles (TDN) have been used antimicrobial agents against several microorganisms but not reported an anti-QS agent. This study aims evaluate...

This study aims to investigate the effect of foliar application 0.0 and 1.5 mM salicylic acid (SA) under normal [100% field capacity (FC)] reduced irrigation (75 50% FC) on yield, chemical composition antimicrobial activities essential oils (EOs) obtained from leaves flowers Ruta graveolens L. in condition. The highest yields EOs (0.366 0.215% v/w for flowers, respectively) were plants grown FC treated with SA. Similarly, maintained same conditions provided percentage long chain methyl...

Escherichia coli serotype O157: H7 and E. O104: H4 are well known foodborne pathogens causing sever enteric illness. Using bacteriophages as biocontrol agents of some multidrug-resistant (MDR) bacteria has a great attention nowadays. This study aims to test the effect cocktail phages on growth MDR coli. Routine conventional PCR was used confirm identification isolates. Double-layered culture technique isolate from sewage water. Morphology bacteriophage described using transmission electron...

The clinical effectiveness of most the marketed antimicrobials is found to be threatened by rapid emergence multidrug resistant pathogens which increase need find alternatives. Hundred years ago, essential oils have been known for their biologic activities in folkloric medicine many countries. objective our study was investigate antibacterial activity some against different microorganisms and possible effects between tested standard antimicrobials. 11 evaluated Staphylococcus aureus, E....

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Pseudomonas aeruginosa is an opportunistic nosocomial pathogen associated with high morbidity and mortality rates. Combination of antibiotics has been found to combat multi-drug resistant or extensively drug resistance P. aeruginosa. In this study we investigate the in vitro vivo effect amikacin imipenem combination against The checkerboard technique time-killing curve have performed for studies showed synergistic combination. A peritonitis mouse model used evaluation therapeutic efficacy...

This study aims to evaluate the effect of NSAIDs on activity some antibiotics against urinary tract pathogens. Urine samples were collected and cultured cysteine lactose electrolyte deficient (CLED) media MICs for determined using Agar dilution method. The combined effects β-lactam tested standard strains by checkerboard technique. Out 100 (63 female patients 37 male suffering from UTIs), 122 bacterial isolated. E. coli Coagulase negative Staphylococci (CoNS) most common (39.3% 26.2%,...