Silver is a potent antimicrobial agent against variety of microorganisms and once the element has entered bacterial cell, it accumulates as silver nanoparticles with large surface area causing cell death. At same time, becomes reservoir for silver. This study aims to test microcidal effect silver-killed E. coli O104: H4 its supernatant fresh viable cells bacterium some other species, including O157: H7, Multidrug Resistant (MDR) Pseudomonas aeruginosa Methicillin Staphylococcus aureus...

Escherichia (E.) coli can cause intestinal and extra-intestinal infections which ranged from mild to life-threatening infections. The severity of infection is a product many factors including virulence properties antimicrobial resistance.To determine the antibiotic resistance pattern, distribution their association with one another some selected genes.Virulence were analyzed phenotypically while susceptibility was tested by Kirby-Bauer agar disc diffusion method. In addition, 64 E. isolates...

Brevinin-2 related peptide (B2RP; GIWDTIKSMG(10)KVFAGKILQN(20)L.NH(2)), first isolated from skin secretions of the mink frog Lithobates septentrionalis, shows broad-spectrum antimicrobial activity but its therapeutic potential is limited by moderate hemolytic activity. The adopts an alpha-helical conformation in a membrane-mimetic solvent amphipathicity low. Increasing together with hydrophobicity substitutions Lys(16)-->Leu and Lys(16)-->Ala increased approximately fivefold without...

Escherichia coli serotype O157: H7 and E. O104: H4 are well known foodborne pathogens causing sever enteric illness. Using bacteriophages as biocontrol agents of some multidrug-resistant (MDR) bacteria has a great attention nowadays. This study aims to test the effect cocktail phages on growth MDR coli. Routine conventional PCR was used confirm identification isolates. Double-layered culture technique isolate from sewage water. Morphology bacteriophage described using transmission electron...

This study aims to evaluate the effect of NSAIDs on activity some antibiotics against urinary tract pathogens. Urine samples were collected and cultured cysteine lactose electrolyte deficient (CLED) media MICs for determined using Agar dilution method. The combined effects β-lactam tested standard strains by checkerboard technique. Out 100 (63 female patients 37 male suffering from UTIs), 122 bacterial isolated. E. coli Coagulase negative Staphylococci (CoNS) most common (39.3% 26.2%,...

Extensive use of antibiotics for urinary tract infections has led to the emergence drug-resistant microorganisms and one solution this problem is search non-antibiotic compounds that exert anti-bacterial activity through different mechanisms such as non-steroidal anti-inflammatory drugs (NSAIDs). In study, out 100 urine samples; 48 Escherichia coli strains were detected, 47.9% multi-drug resistant. The antibiogram resistance pattern was carried by agar dilution method. Diclofenac sodium,...

Pseudomonas aeruginosa is an opportunistic pathogen that can cause a variety of diseases especially in the hospital environment. However, this also exhibits antimicrobial activity against Gram-positive bacteria and fungi. This study aimed to characterize different virulence factors, secreted metabolites their role suppression Candida growth. Fifteen P . isolates were tested for anticandidal 3 spp. by cross-streak method. The effect on hyphae production was microscopically using light...

Antibiotic resistance genes (ARGs) transfer rapidly among bacterial species all over the world contributing to aggravation of antibiotic crisis. Antibiotics at sub-inhibitory concentration induce horizontal gene (HRT) between bacteria, especially through conjugation. The role common non-antibiotic pharmaceuticals in market disseminating is not well studied.

In this research, radon concentrations were measured in schools Wasit city Iraq, where gas concentration levels for 40 city, and the results indicated that ranged between 3.000-50.00 Bq/m 3 with an average value of 18.05±1.728 , some radiation coefficients related to as annual effective dose (AED) given students staff from each school was much lower than ICRP limit 1993 (3-10) mSv/year is now about 0.3935 ± 0.046 All AED values are The pulse 1.165 0.12 spep/year paec 1.4863, which shows...

Silver nanoparticles (AgNPs) are considered a good alternative for antibiotics due to emerging Multidrug Resistance (MDR) crisis. AgNPs is approximately limited among Gram-positive and Gram-negative pathogens. Low toxicity human cells permits its safe use as new antimicrobial with broad spectrum. Bacterial used factory synthesis supplying powerful eco-friendly way. In this study, MDR Escherichia coli strains were recovered from patients attending Minia University hospital. Biogenic of was...

Mycoplasma pneumoniae is a one of most common reasons respiratory tract infections in both adolescents and children with severity ranged from moderate to high. Many facts the previous years regarding were induced via this organism having extra pathogenic mechanisms. Clinically, resistance macrolide has produced internationally represents treatment trouble. Antimicrobial sensitivity checking out techniques have been applied, novel antibiotics which are effective towards M. present processing...

Objectives: Non steroidal anti-inflammatory drugs (NSAIDs) are commonly used in market to treat inflammatory diseases by inhibiting cyclooxygenase (COX), the rate- limiting enzyme prostaglandins (PGs) synthesis. There constitutive expression of COX-1 most cells and inducible COX-2 at sites. In recent years NSAIDs like ketoprofen diclofenac begin show an immunomodulatory activity predicting its promising use treatment autoimmune disorders. present study, we investigate role both...