A5091018794- Essential Oils and Antimicrobial Activity
- Microbial Natural Products and Biosynthesis
- Probiotics and Fermented Foods
- Fungal Biology and Applications
- Medicinal Plants and Neuroprotection
- Bacterial biofilms and quorum sensing
- Wound Healing and Treatments
- Antibiotic Resistance in Bacteria
- Marine Sponges and Natural Products
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Meat and Animal Product Quality
- Phytochemistry and Bioactivity Studies
- Mesenchymal stem cell research
- Moringa oleifera research and applications
- Microbial Metabolism and Applications
- Advanced Drug Delivery Systems
- Escherichia coli research studies
- Edible Oils Quality and Analysis
- Nail Diseases and Treatments
- Quinazolinone synthesis and applications
- Synthesis of Tetrazole Derivatives
- Bioactive Compounds and Antitumor Agents
- Dental Anxiety and Anesthesia Techniques
- Vector-Borne Animal Diseases
Minia University
2020-2025
Deraya University
2020-2025
Assiut University
2024
Czech Academy of Sciences, Institute of Microbiology
2020
Poultry meat is commonly marketed at refrigerated temperatures (2–5 °C). The major concern for retailers and consumers the quality safety of poultry meat. During chilling period, undergoes too many undesirable changes due to microbial growth that leads spoilage economic loss. Therefore, this study was conducted assess effects olive leaf extracts (OLE) used three concentrations (0.25, 0.5, 1%) on sensory attributes, as well chemical microbiological raw stored 4 ± 1 °C 15 days. results...
Vitis vinifera Egyptian edible leaf extract loaded on a soybean lecithin, cholesterol, and Carbopol gel preparation (VVL-liposomal gel) was prepared to maximize the in vivo wound healing anti-MRSA activities for crude extract, using an excision model focusing TLR-2, MCP-1, CXCL-1, CXCL-2, IL-6 IL-1β, MRSA (wound infection model, peritonitis model). VVL-liposomal stable with significant drug entrapment efficiency reaching 88% ± 3, zeta potential value ranging from -50 -63, size range of...
Background and aim: Brevundimonas spp. are ubiquitous in the environment, but they infrequently isolated from clinical specimens. cause bacteremia sepsis, less frequently pneumonia, which resist numerous antibiotics, such as fluoroquinolone beta lactams. The aim of this study was to investigate epidemiological distribution NDM-1 gene metallo-β-lactamase-producing diminuta/vesicularis isolates pediatric patients with bloodstream infections. Methods: Totally, 384 blood samples were collected...
Bacillus species are widely distributed microorganisms in nature that responsible for outbreaks of food poisoning and a common cause spoilage. This study aimed to isolate identify foodborne from meat determine the antimicrobial activities commercial essential oils spices powder extracted certain medicinal plants.Sixty samples were collected Assiut city subdivided into raw processed meat. spp isolated identified according their cultural characters, biochemical reactions, serological typing,...
The poultry meat and its products are considered ideal media for bacterial growth spoilage, as they highly nutritive with a favorable pH. food industry has focused attention on great diversity of plant species preservatives. aim this study was to investigate the presence Staphylococcus aureus, Escherichia coli O157: H7, Klebsiella pneumonia in samples evaluate antibacterial activity some medicinal extracts against these bacteria. Raw processed (n = 60) were collected from abattoirs...
Cancer continues to be one of the biggest causes death that affects human health. Chemical resistance is still a problem in conventional cancer treatments. Fortunately, numerous natural compounds originating from different microbes, including fungi, possess cytotoxic characteristics are now well known. This study aims investigate anticancer prospects five fungal strains were cultivated and isolated Red Sea soft coral Paralemnalia thyrsoides. The vitro potential ethyl acetate extracts...
Otomycosis is a serious superficial mycotic infection of the outer ear canal caused by some pathogenic species Candida and Aspergillus. The remains challenge to clinicians owing incomplete efficacy market-available antifungal agents high recurrence rates. Moringa oleifera leaf ethanol extract showed against albicans SC5314, compared Nystatin® as reference with MIC values 7 718.33 μg ml-1, respectively. was mixed lecithin chitosan give core/shell giant nanoparticles, good zeta potential...
Endophytic fungi, particularly from higher plants have proven to be a rich source of antimicrobial secondary metabolites. The purpose this study is examine the potential three endophytic fungi Aspergillus sp. SA1, SA2, and SA3, cultivated Nigella sativa seeds against Staphylococcus aureus (ATCC 9144), Escherichia coli 25922), Pseudomonas aeruginosa 27853), Klebsiella pneumoniae 13883), MRSA 33591), human pathogen Candida albicans 10231). Furthermore, most active were molecularly identified...
Abstract In the current study, we evaluated in vitro antibacterial efficacy of roots’ extracts Jasminum officinale , Rosa damascene and Paeonia officinalis against MRSA (methicillin-resistant Staphylococcus aureus ) by well diffusion technique. The root extract P. exerted a potent anti-MRSA with MIC 0.4673 µg/ml, while both J. R. exhibited very weak activity. Therefore, chemical profiling crude roots assisted LC-HR-ESI-MS was performed led to dereplication twenty metabolites different...
In Uganda, bovine babesiosis continues to cause losses the livestock industry because of shortages cheap, quick, and reliable diagnostic tools guide prescription measures. this study, presence antibodies Babesia bigemina bovis in 401 blood samples obtained from eastern central areas Uganda were detected using enzyme-linked immunosorbent assays (ELISAs) immunochromatographic test strips (ICTs). The ELISA ICT used targeted B. C-terminal rhoptry-associated protein (RAP-1/CT17) spherical body...
NS5B polymerase inhibitors represent the cornerstone of present treatment Hepatitis C virus infection (HCV). Naturally occurring substitution mutations to have been recorded. The current study intended demonstrate possible natural direct acting antiviral (DAA)-mutations HCV region in patients Minia governorate, Egypt.Samples were collected from 27 treatment-naïve and 8 non-responders. Out patients, 17 sequences (amino acids 221-345) one sample non-responders successfully amplified....
Cancer is a hazard life-threatening disease, which affect huge population worldwide. Marine actinomycetes are considered as promising source for potential chemotherapeutic agents. In our study, we carried out metabolic profiling Nocardia sp. UR 86 and Nocardiopsis 92 that were cultivated from the Red Sea sponge Amphimedon to investigate their chemical diversity using different media conditions. The crude culture extracts subjected high-resolution mass spectrometry (HRMS) analysis. profiles...
Endophytic fungi are known to be a rich source of anti-infective drugs. In our study, Allium cepa was investigated for fungal diversity using different media give 11 isolates which were identified morphologically. Out the isolated strains, Penicillium sp. (LCEF10) revealed potential activity against tested microbes (Fusarium solani ATTC 25922, Pseudomonas aeruginosa (ATTC 29231), Staphylococcus aureus 27853, Candida albicans 10231), besides, their MICs measured by well diffusion method,...
Endophytic fungi are very rich sources of natural antibacterial and antifungal compounds. The main aim this study is to isolate the fungal endophytes from medicinal plant Corchorus olitorius seeds (F. Malvaceae), followed by antimicrobial screening against various bacterial strains.Seven endophytic strains belonging different three genera were isolated, including Penicillium, Fusarium, Aspergillus. seven isolated revealed selective noticeable activity Escherichia coli (ATCC25922) with varied...
Antibiotic resistance genes (ARGs) transfer rapidly among bacterial species all over the world contributing to aggravation of antibiotic crisis. Antibiotics at sub-inhibitory concentration induce horizontal gene (HRT) between bacteria, especially through conjugation. The role common non-antibiotic pharmaceuticals in market disseminating is not well studied.
Metabolic profiling of the ethyl acetate extract Corchorus olitorius seeds associated with Penicillium sp. resulted in dereplication sixteen compounds (1–16). The present work investigated combined wound-healing potential BMMSCs and immunocompromised rats. BMMSCs/Penicillium combination could attenuate oxidative stress, pro-inflammatory cytokines, NF-KB activation, at day 16. Network pharmacology identified ten key genes connected to process: AKT1, TNF, STAT3, TP53, IL1B, MMP9, CASP3, PTGS2,...
Introduction:Local antibiotic administration has been investigated in addition to employing laser disinfection light of the progress non-instrumentation endodontic treatment, lesion sterilization, and tissue healing.Methods: 96 single-rooted teeth were collected.At CEJ point, their crowns severed.The root canals prepared work up file F3 ProTaper length.The smear layer was removed using EDTA 17% sodium hypochlorite 2.5% for 5 minutes, composite then utilized close apical foramen.The...
Rheumatoid arthritis (RA) is a systemic inflammatory disease with chronic nature of joints related to autoimmunity. Vitamin D was found modulate cell growth, function immune cells and anti-inflammatory action. The aims that study were investigate serum level vitamin some cytokines identify the correlation between these in RA. Totally 40 RA patients without supplement involved this study. Serum D, interleukin-6 (IL-6), IL-10, IL-35, C-reactive protein (CRP) tumor necrosis factor α (TNF-α),...