A5082003723- Cervical Cancer and HPV Research
- Reproductive tract infections research
- HIV-related health complications and treatments
- Viral-associated cancers and disorders
- Cardiovascular Health and Risk Factors
- Global Cancer Incidence and Screening
- Diabetes, Cardiovascular Risks, and Lipoproteins
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- Health disparities and outcomes
- Hepatitis B Virus Studies
- Global Public Health Policies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Genital Health and Disease
University of Bern
2024-2025
Institute of Social and Preventive Medicine
2024-2025
London School of Hygiene & Tropical Medicine
2020
Purpose The NCDzz study is a prospective cohort of people living with and without HIV attending primary care clinics in Zambia Zimbabwe was established 2019 to understand the intersection between noncommunicable diseases (NCDs) Southern Africa. Here, we describe design population evaluate their ideal cardiovascular health (ICVH) using Life’s Simple 7 (LS7) score according American Heart Association. Participants Antiretroviral therapy-naïve (PLWH) (PLWOH) 30 years or older were recruited...
Countries with high HIV prevalence, predominantly in sub-Sahahran Africa, have the highest cervical cancer rates globally. care cascades successfully facilitated scale-up of antiretroviral therapy. A cascade approach could similarly succeed to screening, supporting WHO’s goal eliminate cancer. We defined a Cervical Cancer Screening Cascade for women living (WLHIV), evaluating continuum screening integrated into an clinic Zimbabwe. included WLHIV aged ≥18 years enrolled at Newlands Clinic...
Abstract Introduction Chronic viral replication has been linked to an increased risk of cardiovascular and metabolic diseases in people living with HIV (PLWH), but few studies have evaluated this association Southern Africa. We explored the determinants syndrome (MetS) among treatment‐naïve adults without Methods Treatment‐naïve PLWH (PLWOH) ≥30 years were consecutively enrolled from primary care clinics Zambia Zimbabwe. PLWOH seronegative partners or persons presenting for testing. defined...
Abstract Introduction Liver disease is a leading cause of morbidity and mortality among persons living with HIV (PLHIV). While chronic viral hepatitis has been extensively studied in low‐ middle‐income countries (LMICs), there limited information about the burden metabolic disorders on liver PLHIV. Methods We conducted cross‐sectional analysis baseline data collected between October 2020 July 2022 from IeDEA‐Sentinel Research Network, prospective cohort enrolling PLHIV ≥40 years...
Coinfection rates of HIV and sexually transmitted infections (STIs) are not widely reported in Zimbabwe no local guidelines regarding the screening STIs people living with exist.This cross-sectional study was conducted to determine prevalence associated risk factors for STI coinfection a cohort HIV-infected women.Between January June 2016, 385 women presenting routine cervical cancer were tested five STIs: Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Trichomonas vaginalis (TV),...
Human papillomavirus (HPV) associated invasive cervical cancer (ICC) is common in Zimbabwe, disproportionately affecting women living with HIV (WLHIV). Understanding high-risk HPV (hrHPV) infection relation to disease important for ICC prevention amongst WLHIV.To describe the prevalence of hrHPV, type distribution, risk factors and screening outcomes an urban cohort Zimbabwean women.In this study, WLHIV were tested hrHPV using Cepheid Xpert® assay followed up incident disease. Follow-up...
Abstract Background People living with HIV (PLWH) are at increased risk of developing cancer. Cancer diagnoses often incompletely captured antiretroviral therapy (ART) clinics. Aim To estimate the incidence and explore factors cancer in a cohort PLWH Harare using probabilistic record linkage (PRL). Methods We conducted retrospective study that included aged ≥16 years starting ART between 2004 2017. used PRL to match records from Zimbabwe National Registry (ZNCR) electronic medical an clinic...
Background: Women living with HIV (WLWH) are six times more likely to develop cervical cancer (CC). There is also an increased incidence of CC in women optimal disease control, despite immune reconstitution due antiretroviral therapy (ART).Objectives: This study describes the prevalence and age-specific genotype distribution hrHPV among urban cohort WLWH. Additionally, we report profile outcomes DNA screening WLWH attending routine at Newlands Clinic, Harare, between January December...
Background. We defined a cascade of cervical screening to evaluate the number women living with HIV (WLHIV) achieving each stage at an care and treatment clinic in Zimbabwe. Methods. included aged ≥18 years enrolled Newlands Clinic Harare from June 2012 2017 followed them until 2018. The consists preventative arms based on initial results. report percentages, median time reach stages, cumulative incidence two 95% confidence intervals (CI). Results. A total 1624 were study. In arm, was 85.4%...