Rael J. Too

ORCID: 0000-0001-6100-9090
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About
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Research Areas
  • Vibrio bacteria research studies
  • Viral gastroenteritis research and epidemiology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Fecal contamination and water quality
  • Salmonella and Campylobacter epidemiology
  • Antibiotic Resistance in Bacteria
  • Escherichia coli research studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacteriophages and microbial interactions

Kenya Medical Research Institute
2018-2024

University of Nairobi
2023-2024

The Ohio State University
2023-2024

Kema International (Netherlands)
2017

Blood and bone marrow cultures are considered the gold standard for diagnosis of typhoid, but these methods require infrastructure skilled staff that not always available in low- middle-income countries where typhoid is endemic. The objective study to evaluate sensitivity specificity nine commercially Salmonella Typhi rapid diagnostic tests (RDTs) using blood culture as a reference multicenter study.

10.1128/jcm.01000-22 article EN cc-by Journal of Clinical Microbiology 2022-11-30

As safe agents of last resort, carbapenems are reserved for the treatment infections caused by multidrug-resistant organisms. The impact β-lactam antibiotics, cefotaxime, and meropenem on frequency diversity carbapenemase-producing organisms recovered from environmental samples has not been fully established. Therefore, this methodological study aimed at determining drugs used in selective enrichment their recovery Enterobacterales (CPE) untreated wastewater. We a longitudinal design where...

10.1371/journal.pone.0281909 article EN public-domain PLoS ONE 2023-02-22

Carbapenem-resistant bacteria (CRB) present a significant global public health concern. Sub-Saharan Africa has borne heavy burden of CRB with reported prevalence up to 60% in some patient populations. es focus on clinical isolates, limited data their spread the natural environment. Therefore, purpose this study was report recovery from Nairobi River surface waters and nearby anthropogenic zoonotic sources County, Kenya. A total 336 were recovered (250 mL) samples, 230 samples (68.5%)...

10.1371/journal.pone.0310026 article EN public-domain PLoS ONE 2024-11-14

Background: Shiga toxin-producing Escherichia coli are among the most important causes of food-borne diseases. They cause illnesses ranging from mild diarrhea to more severe conditions that may progress hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The burden STEC in patients with diarrheal illness Kitale county referral hospital, Trans-Nzoia County had not been established. This study was aimed at determining prevalence STEC, its associated virulence genes antimicrobial...

10.1016/j.ijid.2018.04.3782 article EN cc-by-nc-nd International Journal of Infectious Diseases 2018-07-27

Abstract Blood and bone marrow cultures are considered the gold standard for diagnosis of typhoid, but those methods require infrastructure skilled manpower that not always available in low- middle-income countries where typhoid is endemic. The objective study to evaluate sensitivity specificity nine commercially Salmonella Typhi rapid diagnostic tests (RDTs) using blood culture as reference a multicenter study. This was prospective retrospective accuracy conducted two geographically distant...

10.1101/2022.07.17.22277655 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2022-07-18
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