A5101597029- Escherichia coli research studies
- Colorectal Cancer Screening and Detection
- Chromosomal and Genetic Variations
- Global Cancer Incidence and Screening
- Urinary Tract Infections Management
- Economic and Financial Impacts of Cancer
- Enterobacteriaceae and Cronobacter Research
- Erythropoietin and Anemia Treatment
- Genetic factors in colorectal cancer
- Plant Virus Research Studies
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Attention Deficit Hyperactivity Disorder
- Cancer-related Molecular Pathways
- Plant-Microbe Interactions and Immunity
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Plant Pathogenic Bacteria Studies
- Child and Adolescent Psychosocial and Emotional Development
- Advanced Breast Cancer Therapies
- Antibiotic Resistance in Bacteria
- Healthcare professionals’ stress and burnout
- Posttraumatic Stress Disorder Research
- HER2/EGFR in Cancer Research
- Medical Imaging Techniques and Applications
New York City Department of Health and Mental Hygiene
2020-2021
Carolinas Medical Center
2020
Levine Cancer Institute
2020
Elizabeth City State University
2019
University Medical Center of El Paso
2019
Directorate-General for Interpretation
2018
Russian State Library
2018
University Hospitals of North Midlands NHS Trust
2018
Queen Elizabeth Hospital
2018
University Hospitals Plymouth NHS Trust
2018
Amore convenient assay is needed for the three recognized allelic variants of papG, which encode Gal(α1–4)Gal-binding adhesin molecules P fimbriae uropathogenic Escherichia coli. The development and validation a novel multiply primed polymerase chain reaction (PCR) described. was 100% sensitive specific papG variants, whether present individually or in any combination. PCR products "class I" (papGJ96), II" (papGIA2), III" (prsGJ96) alleles could be resolved by size same lane using agarose...
The distribution of the three alleles P adhesin gene papG (classes I–III) was assessed among 74 Escherichia coli urine isolates from women with first-episode or recurrent cystitis, and genotype compared clinical origin, O serogroup, agglutination Gal(α1–4)Gal-coated latex beads human sheep erythrocytes, hemolysin production. class-III-only (27% strains) predominated over I + III (3%) II-only (7%) genotypes, irrespective category. In contrast to class II allele, allele significantly...
The prevalence of colonization with uropathogenic Escherichia coli and their reservoirs routes acquisition are incompletely defined. To help clarify these issues, polymerase chain reaction (PCR)-based strain typing assays were used to evaluate the fecal vaginal E. flora 11 volunteers. PCR detected virulence genes papG, aer, cnf significantly more frequently in mixed intestinal samples than corresponding predominant strains, evidence that traditional methods suboptimal for detecting...
Abstract Background Although colorectal cancer screening has contributed to decreased incidence and mortality, disparities are present by race/ethnicity. The Citywide Colon Cancer Control Coalition (C5) NYC Department of Health Mental Hygiene (DOHMH) promoted colonoscopy from 2003 on, hypothesized future reductions in CRC incidence, mortality racial/ethnic disparities. Methods We assessed annual percent change (APC) stage rates through 2016 a longitudinal cross-sectional study NY State...
The pyelonephritis-associated adhesin gene papG of Escherichia coli occurs in three variants. Whereas the class II and III variants are common among human urinary tract infection isolates, I allele, despite being first cloned, has previously been found only source strain J96. Five strains have discovered from geographically diverse locales that, like J96, contain both alleles. One caused bacteremia, whereas 4 cystitis. Like all 5 had group capsule genes, expressed H5 flagellar antigen F13...
Adult attention-deficit/hyperactivity disorder (ADHD) is a common neuropsychiatric disorder, yet only 1 in 10 affected adults receives treatment. The study objective was to assess gaps knowledge and describe current practice patterns of primary care physicians psychiatrists the United States management adult patients with ADHD.Primary completed an Internet survey as needs assessment customary related ADHD. clinical case vignettes were followed by practice, confidence, barrier questions....
We report familial adenomatous polyposis coli (FAPC) with epidermoid cysts, osteomata, and areas of congenital hypertrophy the retinal pigment epithelium (CHRPEs) in a male patient his maternal aunt, both whom suffered mild to moderate degree mental handicap. Both had an interstitial deletion long arm chromosome 5 (del(5)(q22q23.2)). Two other normal family members underlying direct insertion 5(dir ins(5)(q31.3q22q23.2)). Molecular genetic fluorescent hybridisation studies have shown that...
Abstract The Mutator system of transposable elements is characterized by a family transposons called Mu that share common termini and are actively transposing in Robertson's (Mu) lines maize. lose transposition activity during propagation either outcrossing or inbreeding. This loss activity, which can occur at non-Mendelian frequencies, the form forward resulting decrease generation new mutations, as well mutability transposon induced it has been correlated with hypermethylation elements....
Receptor specificities of the three recognized variants PapG, major adhesin uropathogenic Escherichia coli, have been deduced in part from distinctive hemagglutination (HA) patterns these adhesins ostensibly exhibit with different erythrocytes. A comprehensive reevaluation HA using sheep, rabbit, and diverse human erythrocytes revealed that erythrocyte binding ranges PapG are broader more overlapping than generally recognized, suggestive receptor beyond those posited prevailing model....
Abstract Background: Resistance to endocrine therapy remains a major clinical challenge with aberrant PI3K/ mTOR pathway activation being one of the main drivers. Randomised trials have demonstrated substantial benefit adding everolimus therapy. Vistusertib (AZD2014), dual inhibitor mTORC1 and mTORC2, has shown broader range activity in preclinical ER+ breast cancer models, showing superior (EVE) both hormone-sensitive resistant models. The MANTA trial was desgined evaluate safety efficacy...
Considering the paucity of data relating erythropoiesis-stimulating agent (ESA) use to ovarian cancer survival, our objective was evaluate effect ESA as used for treatment chemotherapy-induced anemia (CIA) on survival in patients.A multi-institution retrospective chart review performed patients. Data collection included patient demographic, surgicopathologic, chemotherapy, ESA, and data. Patients were stratified by ever-use compared using appropriate statistical methods.A total 581 patients...
Posttraumatic stress disorder (PTSD) is a signature injury of war among returning soldiers and US National Guard Reserve members, with symptoms even more likely on rescreening. Studies that examine health care provider screening referral practices outside the military for these patients are needed. The objective this study was to assess PTSD barriers care.A 25-item, anonymous Internet questionnaire developed as an educational needs assessment survey based Department Veterans Affairs Defense...
Colorectal cancer (CRC) incidence rates are rising in younger Americans and mortality increasing among white Americans. We used New York State Cancer Registry data to examine City CRC trends adults ages 20-54 years by race from 1976 2015. Annual percent change (APC) was considered statistically significant at P less than .05 using a two-sided test. increased those 20-49 years, yet blacks had the largest APC of 2.2% (1993-2015; 95% confidence interval [CI] = 1.4% 3.1%) compared with 0.5%...
Abstract Background Racial disparities in New York City (NYC) breast cancer incidence and mortality rates have previously been demonstrated. Disease stage at diagnosis mortality‐to‐incidence ratio (MIR) may present better measures of differences screening treatment access. Racial/ethnic trends NYC MIR not assessed. Methods Mammogram were compared using the Community Health Survey, 2002‐2014. Breast diagnosis, stage, from State Cancer Registry, 2000‐2016. Primary outcomes MIR, age‐adjusted to...
e16510 Background: Cancer-related anemia (CRA) is common in hematological malignancies and some solid tumors. The purpose of this study was to describe the resource utilization costs cancer patients with (CPWA) without (CPWoA) overall a subgroup who received chemotherapy during period. Methods: De-identified data from large administrative claims database (Thomson Reuters MarketScan) used for retrospective study. This included ≥ 18 years, diagnosis (ICD-9 codes 140.x - 208.x, 230.x 239.x)...
EVIDENCE-BASED ANSWER The available options are only somewhat useful. Cornell Scale for Depression in Dementia (CSDD) is marginally sensitive diagnosing depression patients with dementia, a positive likelihood ratio (LR+) of 1.6. Geriatric (GDS-30) correlates moderately the CSDD mild cognitive impairment but weakly Alzheimer's dementia (SOR: B, prospective cohort studies).