A5006879220- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Dermatology and Skin Diseases
- Orthodontics and Dentofacial Orthopedics
- Cellular Mechanics and Interactions
- Sex work and related issues
- Bone fractures and treatments
- Temporomandibular Joint Disorders
- Elasticity and Material Modeling
- Xenotransplantation and immune response
- Female Genital Mutilation/Cutting Issues
- Additive Manufacturing and 3D Printing Technologies
- Immunodeficiency and Autoimmune Disorders
- Body Image and Dysmorphia Studies
- Hip disorders and treatments
- Mesenchymal stem cell research
- Patient-Provider Communication in Healthcare
- Psoriasis: Treatment and Pathogenesis
- Urticaria and Related Conditions
- Craniofacial Disorders and Treatments
École Nationale Supérieure de Techniques Avancées
2022-2024
Institut Necker Enfants Malades
2022-2024
Assistance Publique – Hôpitaux de Paris
2022-2024
Université Paris Cité
2023-2024
Hôpital Beaujon
2021-2023
Hôpital Necker-Enfants Malades
2023
Institut des Sciences de la Mécanique et Applications Industrielles
2022
Last twenties, tissue engineering has rapidly advanced to address the shortage of organ donors. Decellularization techniques have been developed mitigate immune rejection and alloresponse in transplantation. However, a clear definition effective decellularization remains elusive. This study compares various protocols using human fascia lata model. Morphological, structural cytotoxicity/viability analyses indicated that all five tested were equivalent met Crapo's criteria for successful...
Introduction Large bone defects are challenging for surgeons. Available reimplanted substitutes can’t properly restore optimal function along and long term osteointegration of the graft. Bone substitute based on perfusion-decellularization technique seem to be interesting in order overcome these limitations. We present here an evaluation biomechanics bones thus obtained. Material methods Two decellularization protocols were chosen this study. One using Sodium Dodecyl Sulfate (SDS) (D1) one...
In terms of large bone defect reconstructions, massive allografts may sometimes be the only solution. However, they are still burdened with a high postoperative complication rate. Our hypothesis is that immunogenicity residual cells in graft involved this issue. Decellularization by perfusion might therefore answer to process and create more biologically effective allografts. Seventy-two porcine bones were used characterize efficiency our sodium hydroxide-based decellularization protocol. A...
Introduction: The human fascia lata (HFL) is used widely in reconstructive surgery indications other than fracture repair. goal of this study was to compare microscopic, molecular, and mechanical properties HFL periosteum (HP) from a bone tissue engineering perspective. Material Methods: Cadaveric HP (N = 4 each) microscopic morphology characterized using histology immunohistochemistry (IHC), the extracellular matrix (ECM) ultrastructure assessed by means scanning electron microscopy (SEM)....
Many assays are available on cerebrospinal fluid (CSF) for the diagnosis of neurosyphilis (NS) but there is no 'gold standard'.The aim this study was to evaluate different molecular and serological used in NS.We evaluated two PCR three techniques parallel CSF samples collected between 2019 2020 from patients suspected NS.The included 143 comprising 30 early NS, 7 late NS 106 without a NS. All with were symptomatic had either neurological (67.6%) or ophthalmological signs (54.1%). The qPCR...
A machine learning inspired method to mimic the mechanical behaviour of biological soft tissues is described. The tuned composite, based on Bézier curves, gives good results in experimental reproduction mandibular and calvarial periosteum.
Objectives We evaluated a real-time quantitative PCR (qPCR) for detection of the Treponema pallidum (TP) genome in clinical samples through simultaneous two genomic targets. Methods performed qPCR with TaqMan technology using TP genes, polA and tpp47 , as targets, an internal positive control. The assay was compared syphilis diagnosis based on combination examination, serological results inhouse nested (nPCR). Samples were analysed at National Reference Center STIs Cochin Hospital Paris....