A5046510673- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Prenatal Substance Exposure Effects
- Neurotransmitter Receptor Influence on Behavior
- Pharmaceutical Practices and Patient Outcomes
- Pain Management and Opioid Use
- Cannabis and Cannabinoid Research
- Mental Health Treatment and Access
- Neuropeptides and Animal Physiology
- Schizophrenia research and treatment
- Forensic Toxicology and Drug Analysis
- Pharmacological Effects and Toxicity Studies
- Cardiac pacing and defibrillation studies
- HIV Research and Treatment
- Treatment of Major Depression
- Pain Mechanisms and Treatments
- Stress Responses and Cortisol
- Cardiac Arrest and Resuscitation
- Health Policy Implementation Science
- Cardiac electrophysiology and arrhythmias
- Diet and metabolism studies
- Healthcare professionals’ stress and burnout
- Alcohol Consumption and Health Effects
Hennepin Healthcare Research Institute
2018-2024
University of Minnesota
2012-2024
Medtronic (Ireland)
2024
University of Minnesota Medical Center
2023-2024
Hennepin County Medical Center
2010-2023
MultiCare Health System
2022
Henry Ford Health System
2022
Kaiser Permanente Washington Health Research Institute
2022
Kaiser Permanente
2022
HealthPartners
2022
The use of naltrexone plus bupropion to treat methamphetamine disorder has not been well studied. We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the a sequential parallel comparison design evaluate efficacy and safety extended-release injectable (380 mg every 3 weeks) oral (450 per day) in adults moderate or severe disorder. In first stage trial, participants were randomly assigned 0.26:0.74 ratio receive naltrexone-bupropion matching placebo for 6 weeks....
<h3>Importance</h3> Despite indications of increasing amphetamine availability and psychostimulant deaths in the United States, evidence across data sources is mixed, on amphetamine-related hospitalizations are lacking. <h3>Objective</h3> To clarify trends their clinical outcomes costs States. <h3>Design, Setting, Participants</h3> This repeated, cross-sectional study used hospital discharge from Healthcare Cost Utilization Project National Inpatient Sample. The nationally representative...
Methamphetamine use, with and without opioids, has increased substantially, but little is known about the sociodemographic characteristics, substance use patterns, or health profiles of individuals who methamphetamine. To design effective public interventions, care professionals policymakers need data describing are using methamphetamine in midst opioid crisis.
Objectives. To estimate trends in incidence, outcomes, and costs among hospital deliveries related to amphetamines opioids. Methods. We analyzed 2004-to-2015 data from the National Inpatient Sample, a nationally representative sample of discharges United States compiled by Healthcare Cost Utilization Project, using repeated cross-sectional design. estimated incidence maternal amphetamine or opioid use with weighted logistic regression. measured clinical outcomes multivariable regression...
Abstract Background Hospitalizations involving opioid use disorder (OUD) are increasing. Medications for (MOUD) reduce mortality and acute care utilization. Hospitalization is a reachable moment initiating MOUD arranging ongoing engagement following hospital discharge. Despite existing quality metrics initiation engagement, few hospitals provide based treatment (HBOT). This protocol describes cluster-randomized hybrid type-2 implementation study comparing low-intensity high-intensity support...
Most people with opioid use disorder (OUD) never receive treatment. Medication treatment of OUD in primary care is recommended as an approach to increase access care. The PRimary Care Opioid Use Disorders (PROUD) trial tests whether implementation a collaborative model (Massachusetts Model) using nurse manager (NCM) support medication increases and improves outcomes. Specifically, it care, compared usual the number days for (implementation objective) reduces acute health utilization...
The fourth wave of the opioid crisis is characterized by increased use and co-use methamphetamine. How methamphetamine associated with health care use, housing instability, social service criminal justice involvement has not been studied could inform future interventions partnerships.To estimate across sectors among people who reported past year co-use, or neither nor use.We examined 2015-2018 data from National Survey on Drug Use Health. We used multivariable negative binomial logistic...
In the US, methadone treatment can only be provided to patients with opioid use disorder (OUD) through federal and state-regulated programs (OTPs). There is a shortage of OTPs, racial geographic inequities exist in access treatment. The National Institute on Drug Abuse Center for Clinical Trials Network convened Methadone Access Research Task Force develop research agenda expand create more equitable OUD. This included mechanisms that are available within outside current regulations. task...
Background: The overdose crisis is increasingly characterized by opioid and stimulant co-use. Despite effective pharmacologic treatment for both use disorder (OUD) contingency management disorders, most individuals with these co-occurring conditions are not engaged in treatment. Hospitalization an important opportunity to engage patients initiate treatment, however existing hospital addiction care tailored co-use may meet the needs of this population. Methods: Semi-structured interviews were...
To examine trends in polysubstance use among adults treatment for opioid disorder (OUD) and estimate associations between patterns receipt of medications OUD (MOUD).We conducted a cross-sectional longitudinal analysis admissions from 1992 to 2017 using the Treatment Episodes Data Set-Admissions (N = 9,440,157). We used multiple logistic regression co-use MOUD categories (opioid only, any methamphetamine, cocaine, alcohol, benzodiazepine).Between 2017, involving opioid/cocaine (-17.2...
Abstract Background The prevalence and associated overdose death rates from opioid use disorder (OUD) have dramatically increased in the last decade. Despite more available treatments than 20 years ago, treatment access high discontinuation are challenges, as personalized medication dosing making timely changes when fail. In other fields such depression, brief measures to address these tasks combined with an action plan—so-called measurement-based care (MBC)—have been better outcomes. This...