- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Advanced Chemical Sensor Technologies
- Sensory Analysis and Statistical Methods
- Statistical Methods in Clinical Trials
- Consumer Attitudes and Food Labeling
- Meat and Animal Product Quality
- Global trade and economics
- Sodium Intake and Health
- Probiotics and Fermented Foods
- COVID-19 Clinical Research Studies
- Optimal Experimental Design Methods
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Global Financial Crisis and Policies
- Biosimilars and Bioanalytical Methods
- Sugarcane Cultivation and Processing
- Food composition and properties
- Second Language Learning and Teaching
- Cognitive and developmental aspects of mathematical skills
- Education Methods and Practices
- Single-cell and spatial transcriptomics
- Inhalation and Respiratory Drug Delivery
- Synthesis of Organic Compounds
- Textile materials and evaluations
Monell Chemical Senses Center
2023-2025
University of Alberta
2017-2022
HUTECH University
2020-2021
Ho Chi Minh City University of Technology
2013-2021
Monash University
2020
Merck & Co., Inc., Rahway, NJ, USA (United States)
1993-2001
United States Military Academy
2000
Princeton University
1985
Université Laval
1976
Abstract The bitter taste of medicines hinders patient compliance, but not everyone experiences these difficulties because people worldwide differ in their bitterness perception. To better understand how from diverse ancestries perceive and modifiers, 338 adults, European recent US Canadian immigrants Asia, South Africa, rated the intensity solutions on a 100-point generalized visual analog scale provided saliva sample for genotyping. were five medicines, tenofovir alafenamide (TAF),...
A sample size re-estimation (SSR) design is a flexible, adaptive with the primary purpose of allowing study to be reassessed in mid-course ensure adequate power. In real world drug product, biologic, and device development, there may large uncertainty key factors that drive estimation for confirmatory clinical trial. For example, early phase studies have encouraging results but could shorter duration, or use different endpoint than what required trials. The negative impact high at stage...
Abstract People often confuse smell loss with taste loss, so it is unclear how much gustatory function reduced in patients self-reporting loss. Our pre-registered cross-sectional study design included an online survey 12 languages instructions for self-administering chemosensory tests 10 household items. Between June 2020 and March 2021, 10,953 individuals participated. Of these, 5,225 self-reported a respiratory illness were grouped based on their reported COVID test results: COVID-positive...
Sugar-reduced chocolates with desirable sensory qualities and sweetness can be created using a 3D printer by layering different sugar concentrations. This study aimed to evaluate the temporal profile, perceived intensity, acceptance of prototype sugar-reduced non-sugar-reduced printed chocolates. A consumer panel (n = 72) evaluated profiles six-layered Sensory were determined dominance sensations (TDS), overall five-point intensity scale, liking nine-point hedonic differences among over time...
Temporal sensory methods can be used to highlight the impact of sodium reduction on dynamic profile foods targeted for reduction. Study aims were compare temporal attribute profiles regular and sodium-reduced food products elicited by TDS TCATA, over single multiple oral intakes. A total 20 semi-trained participants evaluated commercially available canned corn, cooked ham (single intakes), potato chips cream mushroom soup (5 intakes) using both TCATA. Regular differed in not only salty but...
Abstract People often confuse smell loss with taste loss, so it is unclear how much gustatory function reduced in patients self-reporting loss. Our pre-registered cross-sectional study design included an online survey 12 languages instructions for self-administering chemosensory tests ten household items. Between June 2020 and March 2021, 10,953 individuals participated. Of these, 3,356 self-reported a positive 602 negative COVID-19 diagnosis (COVID+ COVID-, respectively); 1,267 were...
Although polyester is well known for smelling strongly after wear, little about the propensity of nylon to retain and emit body odor. In this study, we investigated whether odor intensity differed between fabrics. A secondary aim was compare on fabrics frozen prior sensory assessment with stored at room temperature. Eight participants wore T-shirts in underarm. Odor rated by 13 assessors. reduction rate (ORR) measured using ISO 17299-3. Overall, no differences were found polyester. Any two...
In multicentre clinical trials using a common protocol, the centres are usually regarded as being fixed factor, thus allowing any treatment-by-centre interaction to be omitted from error term for effect of treatment. However, we feel it necessary use if there is substantial evidence that with qualitative instead quantitative. To make allowance estimated uncertainties centre means, propose choosing reference value (for example, median ordered array means) and converting individual results...
Introduction There have been large geographical differences in the infection and death rates of COVID-19. Foods beverages containing high amounts phytochemicals with bioactive properties were suggested to prevent contracting facilitate recovery from The goal our study was determine correlation type foods/beverages people consumed risk reduction COVID-19 Methods We developed an online survey that asked participants whether they contracted COVID-19, their symptoms, time recover, frequency...
SCENTinel, a rapid smell test designed to screen for olfactory disorders, including anosmia (no ability an odor) and parosmia (distorted sense of smell), measures 4 components function: detection, intensity, identification, pleasantness. Each card contains one 9 odorant mixtures. Some people born with genetic insensitivities specific odorants (i.e. anosmia) may fail the if they cannot but otherwise have normal smell. However, using mixtures has largely been found prevent this from happening....
Among major contributors of dietary sodium intake, many foods are consumed together with companion foods, specifically condiments and carriers. This study compared sensory profiles overall liking between commercially available regular sodium-reduced or without foods; examined changes in when condiment-carrier pairs. Three distinct consumer panels evaluated one the three pairs, salsa-corn chips (n = 98, 63% female), ketchup-tater tots 100, 69% soy sauce-cooked rice 70% female). For each...
Abstract Two procedures, based on proposals discussed by Mosteller and Tukey, are described for obtaining a combined estimate of the difference between two treatment means its confidence interval from multicentre clinical trial data. Both procedures provide estimates in possible presence heteroscedasticity. The first procedure is designated primary analysis efficacy assessment. It omits treatment‐by‐centre interaction error term treatment, unless there substantial evidence qualitative...
Abstract Purpose There have been large geographical differences in the infection and death rates of COVID-19. Foods beverages containing high amounts phytochemicals with bioactive properties were suggested to prevent contracting, limit severity of, facilitate recovery from The goal our study was determine correlation type foods/beverages people consumed risk reduction contracting COVID-19 Methods We developed an online survey that asked participants whether they contracted COVID-19, their...
Abstract The bitter taste of medicines hinders patient compliance, but not everyone experiences these difficulties because people worldwide differ in their bitterness perception. To better understand how from diverse ancestries perceive and modifiers, 338 adults, European recent US Canada immigrants Asia, South Africa, rated the intensity solutions on a 100-point generalized visual analog scale provided saliva sample for genotyping. were five medicines, tenofovir alafenamide (TAF),...