A5049426484- Testicular diseases and treatments
- Sexual Differentiation and Disorders
- Sarcoma Diagnosis and Treatment
- Sperm and Testicular Function
- Eosinophilic Esophagitis
- Ovarian cancer diagnosis and treatment
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Alcohol Consumption and Health Effects
- Helicobacter pylori-related gastroenterology studies
- Urologic and reproductive health conditions
- Liver Disease Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Male Reproductive Health Studies
- Bladder and Urothelial Cancer Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Potassium and Related Disorders
- Vasculitis and related conditions
- Prostate Cancer Treatment and Research
- Cardiac Structural Anomalies and Repair
- Clinical Reasoning and Diagnostic Skills
- Ethics in Clinical Research
- Diversity and Career in Medicine
The University of Texas Southwestern Medical Center
2020-2025
Southwestern Medical Center
2021-2025
Current serum tumor markers for testicular germ cell are limited by low sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior marker malignant (viable) management. We evaluated real-world application levels in detecting viable among patients undergoing partial or radical orchiectomy.
Safety net hospitals (SNHs) care for a substantial population of vulnerable patients and are often resource-limited. These limitations may impact treatment decisions high-risk prostate cancer (hPCa). We performed the first population-based analysis examining SNH status localized hPCa. National database (NCDB) was queried from 2010-2016 with non-metastatic defined as 95th percentile Medicaid uninsured caseload. Non-curative intent androgen deprivation monotherapy (ADT) or no treatment....
377 Background: The American Joint Committee on Cancer 8 th edition staging guidelines for testicular cancer established a 3 cm cutoff to subclassify stage T1 seminomas (<3 = pT1a and ≥3 pT1b). efficacy of this in predicting metastatic disease impact treatment patterns has not been studied. Methods: We retrospectively reviewed patients with pT1 seminoma the National Database from 2004-2016. Receiver operating curves (ROC) were used determine tumor identifying disease, multivariable...
Studies thus far lacking diversity show many patients with implantable cardioverter defibrillators (ICDs) have poor understanding of ICD functioning, preventing informed decision-making near end life (EOL).To describe knowledge, perceptions, and preferences regarding ICDs among nearing EOL in a diverse, safety-net hospital population.A cross sectional phone survey from was performed. The assessed their ICD.Nearly half (46%) falsely believed turning off shocking function would stop the heart,...
389 Background: Organ confined (stage IA/IB) testicular cancer has a high cure rate regardless of initial treatment modality, making it important to weigh the toxicities against potential benefits. While many clinicians routinely obtain serum tumor markers (STMs) prior radical orchiectomy, their role in predicting recurrence stage IA and IB not been studied. Methods: A multi-institutional database I patients diagnosed between 2006 2018 was created. Univariate multivariate regression models...
387 Background: Current serum tumor markers (STMs) for testicular germ cell (GCT) are limited by low sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior marker malignant (viable) GCT management. We evaluated real-world application levels in detecting viable among patients undergoing partial or radical orchiectomy. Methods: Serum samples were collected from 69 consecutive pre-orchiectomy. Performance characteristics compared with conventional STMs...
Microscopic polyangiitis (MPA) is an autoimmune small-vessel vasculitis often positive for perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA), or anti-myeloperoxidase (MPO), that classically affects the lungs, kidneys, and skin. Several atypical presentations of MPA involving other organs have also been reported in literature. We report a unique case patient who presented with rare MPA: hearing vision loss, dysphagia, renal dysfunction. Despite nature her symptoms, p-ANCA serology was...
430 Background: Molecular features of testicular germ cell tumors (GCT) in various clinical states (pre- vs post-chemotherapy, localized versus metastatic) may inform treatment options for patients with recurrence after definitive therapy. In his study, we describe molecular and potential therapeutic targets a cohort GCT. Methods: We retrospectively examined clinicopathologic next-generation sequencing (NGS) data from 27 Tumors were sequenced using the Tempus|xT solid tumor assay, which...
You have accessJournal of UrologyCME1 Apr 2023MP33-19 MOLECULAR CHARACTERISTICS AND ACTIONABLE TARGETS OF TESTICULAR GERM CELL TUMORS IN REAL-WORLD CONDITIONS Rafael Morales-Grimany, Cesar Delgado, Fady Baky, Armon Amini, Thomas Gerald, Rohit R Badia, Jacob Taylor, Luke L Wang, Juan Javier-Desloges, Vitaly Margulis, Solomon L. Woldu, Amir Salmasi, Fred Millard, Rana R. Mckay, and Aditya Bagrodia Morales-GrimanyRafael Morales-Grimany More articles by this author , DelgadoCesar Delgado...
<ns3:p><ns3:bold>Background</ns3:bold></ns3:p><ns3:p> Student scores on the Learning and Study Strategies Inventory (LASSI), an assessment of academic skills, have been shown in previous studies to be significantly different between U.S. medical students based their various examinations during pre-clerkship curriculum. This study aimed evaluate LASSI other early performance markers for predicting likelihood shelf exam underperformance third-year students.</ns3:p><ns3:p> <ns3:bold>Methods...
245 Background: SBRT for localized prostate cancer (PCa) is the focus of several ongoing and reported high-impact trials, which often on physician-reported toxicity (P-Tox) when comparing regimens. Patient-reported quality life (PR-QoL) may differ provide a more sensitive comparative metric treatment burden, especially with fewer provider interactions during than protracted RT courses. We evaluated concordance prospective genitourinary (GU) gastrointestinal (GI) P-Tox PR-QOL in men receiving...
416 Background: Testicular cancer with retroperitoneal metastases is often treated chemotherapy, subsequent post-chemotherapy lymph node dissection (PC-RPLND) performed for residual masses after chemotherapy. While the cure rate high, surgery associated significant morbidity. Unlike in other genitourinary cancers, perioperative nutritional optimization typically not prioritized as most patients are young, otherwise healthy men. Albumin a systemic marker of status and has been shown to...
383 Background: Nationwide cancer registries such as the National Cancer Database (NCDB) and Surveillance, Epidemiology, End Results (SEER) rely on accurate data from institutional tumor to formulate hypotheses report outcomes treatment patterns for patients with cancer. We evaluated accuracy of our registry testicular germ cell tumors (GCT) by comparing abstracted urologists registry. Methods: performed a retrospective review receiving initial diagnosis at hospital system 2005-2016....