- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- MRI in cancer diagnosis
- Genetic and Kidney Cyst Diseases
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatitis B Virus Studies
- Medical Imaging and Pathology Studies
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Renal cell carcinoma treatment
- Advanced MRI Techniques and Applications
- Ovarian cancer diagnosis and treatment
- Organ Transplantation Techniques and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Radiology practices and education
- Soft tissue tumor case studies
- Abdominal Trauma and Injuries
- Vascular Tumors and Angiosarcomas
- Liver Diseases and Immunity
- Sarcoma Diagnosis and Treatment
- Hepatitis C virus research
- Abdominal vascular conditions and treatments
University of Palermo
2015-2024
University of Palermo
2021-2024
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2004-2024
Université de Yaoundé I
2023
Tecnologie Avanzate (Italy)
2004-2019
University of Pittsburgh Medical Center
2001-2011
La Maddalena
2009-2011
University of Pittsburgh
2002-2009
Gastroenterology Hospital "Saverio de Bellis"
2006-2008
Weatherford College
2007
International guidelines suggest ultrasound surveillance for hepatocellular carcinoma (HCC) early diagnosis in liver cirrhosis (LC) patients, but 40% of nodules < 2 cm escape detection. We investigated the existence an pattern indicating a higher risk developing HCC patients under surveillance. 359 with LC (Child-Pugh A-B8) underwent screening (median follow-up 54 months, range 12–90 months), function tests, alpha-fetoprotein assay, and portal hypertension evaluation . Echo patterns were...
PURPOSE: To evaluate features of focal nodular hyperplasia (FNH) at multiphasic helical computed tomography (CT). MATERIALS AND METHODS: Clinical, pathologic, and preoperative imaging findings were retrospectively reviewed in 78 patients. Conventional liver CT was performed nine patients; CT, 69. Diagnosis based on complete resection (n = 20), biopsy 42), or clinical follow-up for a minimum 6 months 16). Number, size, location, margins, surface, homogeneity enhancement, presence central...
To compare the computed tomographic (CT) appearance of pancreatic unilocular macrocystic serous cystadenoma, mucinous and pseudocyst to determine if there are findings that assist in differential diagnosis.CT 33 patients (24 women, nine men; age range, 18-84 years; mean age, 41 years) with lesions (macrocystic n = 12; 11; pseudocyst, 10) were retrospectively jointly reviewed by two blinded observers. Twenty-three underwent helical CT, which included portal venous phase imaging delays 40...
It is important to recognize the imaging characteristics of peliosis hepatis because peliotic lesions may mimic several different types focal hepatic lesionsWe illustrate spectrum findings hepatis, including sonography, CT, MR, and angiography.
To develop a consensus and provide updated recommendations on liver MR imaging the clinical use of liver-specific contrast agents. The European Society Gastrointestinal Abdominal Radiology (ESGAR) formed multinational panel experts, selected basis literature review their leadership in field imaging. A modified Delphi process was adopted to draft list statements. Descriptive Cronbach’s statistics were used rate levels agreement internal reliability consensus. Three rounds conducted 76...
Purpose To determine in a large multicenter multireader setting the interreader reliability of Liver Imaging Reporting and Data System (LI-RADS) version 2014 categories, major imaging features seen with computed tomography (CT) magnetic resonance (MR) imaging, potential effect reader demographics on agreement preselected nonconsecutive image set. Materials Methods Institutional review board approval was obtained, patient consent waived for this retrospective study. Ten sets, comprising 38-40...
To evaluate the performance of radiologists in diagnosis internal hernia with specific computed tomographic (CT) findings.Abdominal CT scans obtained 42 patients were retrospectively reviewed by three radiologists. The case group consisted 18 hernias (two paraduodenal, 16 transmesenteric); comparison was 24 no hernia. Images a random and blinded fashion. Individual evaluated receiver operating characteristic (ROC) analysis, interobserver agreement measured Cronbach coefficient alpha. signs...
To determine whether gadobenate dimeglumine (Gd-BOPTA) is able to provide morphologic and functional information for characterization of focal nodular hyperplasia (FNH).Sixty-three consecutive patients with proved FNH were retrospectively examined. Magnetic resonance (MR) imaging T2-weighted turbo spin-echo T1-weighted gradient-echo sequences was performed. Images acquired prior during the dynamic phase contrast-material enhancement 1-3 hours after administration 0.1 mmol/kg Gd-BOPTA....
PURPOSE: To investigate the natural history and diagnosis of cavernous hemangioma in cirrhotic liver with computed tomography (CT) magnetic resonance (MR) imaging. MATERIALS AND METHODS: Imaging pathologic findings 21 hemangiomas 17 patients were retrospectively reviewed. CT was performed all patients; MR imaging, four. Cirrhosis confirmed histologically patients, based on histopathologic (15 18 hemangiomas) or strict imaging criteria (two three hemangiomas). Ten underwent follow-up. The...
Helical CT Screening for Hepatocellular Carcinoma in Patients with Cirrhosis: Frequency and Causes of False-Positive InterpretationGiuseppe Brancatelli1, Richard L. Baron1 2, Mark S. Peterson1 3 Wallis Marsh4Audio Available | Share
The purpose of this study was to determine the CT and MR imaging appearance large regenerative nodules arising in livers with vascular disorders correlate these findings clinical pathologic findings.Large are a characteristic feature Budd-Chiari syndrome other hepatic disorders. show consistent features surrounding liver that may allow distinction from types hypervascular hyperplastic or dysplastic nodules.
To evaluate the prevalence of hepatic hemangioma in a large population patients with focal nodular hyperplasia (FNH) and to determine if is higher than that other masses.Over period 40 months, 247 one or more masses underwent magnetic resonance (MR) imaging at our institution met inclusion criteria for this study. One hundred forty-eight received diagnosis FNH (study group). Ninety-nine had lesion no history chronic liver disease (control Imaging findings main presence associated were...
To investigate the clinical course of untreatable hepatocellular carcinoma (HCC) identified at any stage and to identify factors associated with mortality.From January 1999 December 2010, 320 out 825 consecutive patients a diagnosis HCC not appropriate for curative or palliative treatments were followed managed supportive therapy. Cirrhosis was diagnosed by histological features liver function evaluated according Child-Pugh score. The performed Ultra-Sound guided biopsy multiphasic...
We tested whether nonalcoholic fatty liver disease (NAFLD) and/or its histological severity are associated with vascular white matter lesions (WML) in patients biopsy-proven NAFLD and non-NAFLD controls. Data were recorded 79 consecutive NAFLD, 82 controls normal ALT no history of chronic diseases, without ultrasonographic evidence steatosis stiffness value <6 KPa. All subjects underwent magnetic resonance assessment WML classified according to the Fazekas score as absent (0/III), or present...
To measure observer performance at various levels of prevalence.A multiobserver multiabnormality receiver operating characteristic (ROC) study to assess the effect prevalence on was conducted. Fourteen observers, including eight faculty members, two fellows, and four residents, interpreted 1,632 posteroanterior chest images with five by using a nested design. Performance comparisons were accomplished multireader multicase approach from 28% (69 249) 2% (31 1,577) diagnostic accuracy. The mean...
Our aim was to compare retrospectively hepatic venous and delayed phase images for the detection of tumour washout during multiphasic multidetector row CT (MDCT) liver in patients with hepatocellular carcinoma (HCC).30 cirrhotic underwent MDCT 90 days before transplantation. performed contrast medium administration arterial phases, were obtained at 12, 55 120 s after trigger threshold. Two radiologists qualitatively evaluated lesion attenuation. Tumour subjectively objectively....