A5048609769- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- MRI in cancer diagnosis
- Prostate Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Organ Transplantation Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Renal and Vascular Pathologies
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Prostate Cancer Treatment and Research
- Medical Imaging and Pathology Studies
- Adrenal and Paraganglionic Tumors
- Radiation Dose and Imaging
- Urologic and reproductive health conditions
- Advanced MRI Techniques and Applications
- Hormonal Regulation and Hypertension
- Multiple and Secondary Primary Cancers
University of Bologna
2015-2024
Azienda USL di Bologna
2011-2024
Policlinico S.Orsola-Malpighi
2014-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2022
University of Verona
2020-2022
Research Institute of Radiology
2021
University Radiology
2016-2021
Shanghai University of Traditional Chinese Medicine
2020
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2020
Jackson and Tull (United States)
2020
A multicenter analysis was conducted to evaluate the main prognostic factors driving survival after radioembolization using yttrium-90-labeled resin microspheres in patients with hepatocellular carcinoma at eight European centers. In total, 325 received a median activity of 1.6 GBq between September 2003 and December 2009, predominantly as whole-liver (45.2%) or right-lobe (38.5%) infusions. Typically, were Child-Pugh class (82.5%), had underlying cirrhosis (78.5%), good Eastern Cooperative...
Transcatheter arterial chemoembolisation (TACE) is the treatment of choice for intermediate stage hepatocellular carcinoma (HCC). Doxorubicin-loaded drug-eluting beads (DEB)-TACE expected to improve performance conventional TACE (cTACE). The aim this study was compare DEB-TACE with cTACE in terms time-to-tumour progression (TTP), adverse events (AEs), and 2-year survival. Patients were randomised one-to-one undergo or followed-up at least 2 years until death. repeated ‘on-demand’. We...
Abstract In a prospective study, we examined the impact of arterial hypervascularity, as established by European Association for Study Liver (EASL) recommendations, criterion characterizing small (1-3 cm) nodules in cirrhosis. A total 72 (1-2 cm, n = 41; 2.1-3 31) detected ultrasonography 59 patients with cirrhosis were included study. When coincidental hypervascularity was at contrast perfusional and helical computed tomography, lesion considered to be hepatocellular carcinoma (HCC)...
Purpose To determine the accuracy of imaging features, such as tumor dimension, multinodularity, nonsmooth margins, peritumoral enhancement, and radiogenomic algorithm based on association between features (internal arteries hypoattenuating halos) gene expression that authors called two-trait predictor venous invasion (TTPVI), in prediction microvascular (MVI) hepatocellular carcinoma (HCC). Materials Methods This single-center retrospective study was approved by institutional review board,...
Abstract Transarterial chemoembolization (TACE) is commonly used as a bridge therapy for patients awaiting liver transplantation (LT) and downstaging initially not meeting the Milan criteria. The primary aim of this study was to analyze whether difference exists between selective/superselective lobar TACE in determining tumor necrosis by pathological analysis whole lesion at time LT. secondary investigate relationship size capacity induce necrosis. Data were extracted from prospective...
Noninvasive criteria for the diagnosis of hepatocellular carcinoma (HCC) in cirrhosis, recommended by European Association Study Liver (EASL) 2001 and American Diseases (AASLD) 2005, have left a number small liver neoplastic nodules undefined. We designed this prospective study 2003 with aims assessing diagnostic contribution vascular contrast-enhanced techniques investigating possible additional superparamagnetic iron oxide magnetic resonance (SPIO-MR) setting.Between 75 consecutive (10-30...
This multi-centre phase II clinical trial is the first prospective evaluation of radioembolisation patients with colorectal liver metastases (mCRC) who failed previous oxaliplatin- and irinotecan-based systemic chemotherapy regimens. Eligible had adequate hepatic, haemopoietic renal function, an absence major hepatic vascular anomalies hepato-pulmonary shunting. Gastroduodenal right gastric arteries were embolised before arterial administration yttrium-90 resin microspheres (median activity,...
Patients with hepatocellular carcinoma should be managed a multidisciplinary approach framed in network where all the diagnostic techniques and therapeutic resources are available order to provide optimal level of care. Given this assumption, Coordinating Committee Italian Association for Study Liver nominated panel experts elaborate practical recommendations management aiming provide: (1) homogeneous efficacious staging work-up, (2) best treatment choice tailored patient status tumour stage...
Objective Many improvements have been made in diagnosing hepatocellular carcinoma (HCC), but the radiological hallmarks of HCC remained same for many years. We prospectively evaluated imaging criteria HCC, early and high-grade dysplastic nodules (HGDNs) patients under surveillance chronic liver disease, using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) MRI diffusion-weighted imaging. Design Our study population included 420 >1 cm 228 patients. The findings...
Systemic inflammation markers, such as neutrophil-to-lymphocyte ratio (NLR), have recently emerged the prognostic factors for recurrence of liver tumors.We assessed ability NLR and other variables to predict outcomes orthotopic transplantation (OLT) hepatocellular carcinoma (HCC). A retrospective analysis was performed in 219 patients with HCC who underwent OLT between 1997 2009, a median follow-up 40 months.Overall 3- 5-year patient survival rates were 76.6% 70.7%, respectively. Overall...
Noninvasive markers would be useful for the assessment of portal hypertension (PH) and esophageal varices (EV) in patients with cirrhosis. The aim our study was to evaluate performance indocyanine green (ICG) retention test as a noninvasive marker PH EV, measured against gold standards (hepatic venous pressure gradient [HVPG] measurement upper endoscopy). We prospectively enrolled compensated cirrhosis referral unit. All underwent laboratory tests, abdominal ultrasound, gastrointestinal...
Primary aim was to validate the percentage of intrahepatic cholangiocarcinomas (ICC) which have a contrast vascular pattern at enhanced ultrasound (CEUS) risk misdiagnosis with hepatocellular carcinoma (HCC) and, secondary aim, verify if any characteristics in CEUS helps identify ICC.All ICC on cirrhosis seen three Italian centres (Bologna, Milan and Pavia) between 2003 2011, least another imaging technique (CT or MRI) had been performed, were retrospectively identified. Those patients size...
Gadoxetic acid (Gd-EOB-DTPA) is a 'hepatocyte-specific' contrast agent for magnetic resonance (MR) in both the vascular and hepatobiliary phases.To evaluate contribution of phase Gd-EOB-DTPA MR diagnosis small hepatocellular carcinoma (HCC) cirrhotic patients under surveillance.Between 2008 2011, 48 consecutive (10-30 mm) liver nodules were detected 33 patients, who prospectively underwent contrast-enhanced ultrasound (CEUS), Gd-EOB-DTPA-enhanced helical-computed tomography (CT) blind study....