A5066460445- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Helicobacter pylori-related gastroenterology studies
- Liver Diseases and Immunity
- Neurological Complications and Syndromes
- Gastroesophageal reflux and treatments
- Cytomegalovirus and herpesvirus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Systemic Lupus Erythematosus Research
- Gallbladder and Bile Duct Disorders
- COVID-19 Clinical Research Studies
- Organ Donation and Transplantation
- Gastric Cancer Management and Outcomes
- Celiac Disease Research and Management
- Substance Abuse Treatment and Outcomes
- Folate and B Vitamins Research
- Nutrition and Health in Aging
- Hepatitis Viruses Studies and Epidemiology
- Alcohol Consumption and Health Effects
Hospital Universitari i Politècnic La Fe
2015-2025
Instituto de Salud Carlos III
2019-2025
Instituto de Investigación Sanitaria La Fe
2018-2025
Centro de Investigación Biomédica en Red
2024
University of Toronto
2023
University Health Network
2023
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2013-2022
University of Massachusetts Chan Medical School
2022
Chinese University of Hong Kong
2022
University of Modena and Reggio Emilia
2015-2018
Bleeding is a feared complication of invasive procedures in patients with cirrhosis and significant coagulopathy (as defined by routine coagulation tests) used to justify preprocedure use fresh frozen plasma (FFP) and/or platelets (PLT). Thromboelastography (TEG) provides more comprehensive global assessment than tests (international normalized ratio [INR] platelet count), its may avoid unnecessary blood product transfusion (defined this study as INR >1.8 count <50 × 10(9) /L) who will be...
Cardiovascular (CV) events represent major impediments to the long-term survival of liver transplantation (LT) patients. The aim this study was assess whether Framingham risk score (FRS) at can predict development post-LT cardiovascular (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV factors, CVEs occurring after LT (ischemic heart disease, stroke, failure, de novo arrhythmias, peripheral arterial disease) recorded. In total, 250 patients (69.6% men)...
•An international multi-society taskforce evaluated the real impact of first wave SARS-CoV-2 on liver transplantation.•The pandemic detrimentally impacted transplant operations in heavily hit countries.•Transplant centers' resilience led to efficient accommodations clinical practice.•These observations may guide how we handle future emergencies this magnitude. Background and AimsThe global transplantation (LT) practices across world is unknown. The goal survey was assess LT practices.MethodA...
The 2024 Annual Congress of the International Liver Transplantation Society (ILTS) was from May 1-4 th in Houston, Texas, USA, under theme “ Disease and Transplantation: Breaking Barriers Exploring New Frontiers” . In addition to a robust scientific program, congress also hosted hands-on cadaveric robotic liver surgery course, machine perfusion workshop, transesophageal echocardiography course. this report, ILTS Vanguard Basic Sciences Committees present summary proceedings.
Abstract Background Different bismuth quadruple therapies containing proton‐pump inhibitors, salts, metronidazole, and a tetracycline have been recommended as third‐line Helicobacter pylori eradication treatment after failure with clarithromycin levofloxacin. Aim To evaluate the efficacy safety of treatments bismuth, either or doxycycline. Methods Sub‐study Spanish data “European Registry on H Management” (Hp‐EuReg), international multicenter prospective non‐interventional routine clinical...
Background. The influence of sex on primary sclerosing cholangitis (PSC), pre- and postliver transplantation (LT) is unclear. Aims are to assess whether there have been changes in incidence, profile, outcome LT-PSC patients Europe with specific emphasis sex. Methods. Analysis the European Liver Transplant Registry database (PSC registered before 2018), including baseline demographics, donor, biochemical, clinical data at LT, immunosuppression, outcome. Results. analysis (n = 6463, 32% female...
The management of Helicobacter pylori infection has to rely on previous local effectiveness due the geographical variability antibiotic resistance. aim this study was evaluate first and second-line H. treatment in Spain, where empirical prescription is recommended. A multicentre prospective non-interventional registry clinical practice European gastroenterologists concerning (Hp-EuReg) developed, including patients from 2013 until June 2019. Effectiveness evaluated descriptively through a...
Background Data on the true prevalence of hepatitis C virus (HCV) infection in general population is essential. We evaluated a program implementing free universal HCV screening using non-invasive point-of-care test (POCT) (OraQuick-HCV rapid test) oral fluid an urban area Valencia, South-Eastern Spain. Methods A cross-sectional study was performed during 2015–2017. Free offered by regular mail to 11,500 individuals aged 18 and over, randomly selected from all census residents Health...
In Brief Background New direct antiviral agents (DAA) for hepatitis C virus treatment result in sustained virologic response (SVR) most patients. However, predicting the point of no return is still an unmet need those with advanced liver disease. The aim to assess if baseline volume a predictor post-SVR function. Methods Cirrhotic patients assessed transplantation and consecutively treated DAA between September 2014 2015 who achieved SVR were included. Pretreatment (LV) spleen (SV) adjusted...
There is an interest in understanding the association between early calcineurin inhibitors exposure post-liver transplantation (LT) and long-term outcomes. We aimed to analyze this exploring median inhibitor levels intrapatient variability (IPV) a multicenter, retrospective cohort.Tacrolimus (Tac) Cyclosporine (CsA) obtained during first 15 days post-LT were collected. High immunosuppression (IS) was considered as of Tac, CsA blood trough 12 hours after drug administration, or 2...
Introduction: metabolic syndrome (MS) and cardiovascular risk factors are common in liver transplant (LT) candidates recipients.Cardiovascular events de novo tumors increasingly causes of mortality recipients.The aims this study were i) to assess the prevalence MS LT recipients its growth over years, ii) determine if presence pre-LT is associated with a higher post-LT (CVE), tumors, or early late survival.Patients methods: retrospective was performed that included from January 2012 December...
Background Despite the WHO's report of 24 available SARS-CoV-2 vaccines, limited data exist regarding vaccination policies for liver transplant (LT) patients. To address this, we conducted a global multi-society survey (EASL-ESOT-ELITA-ILTS) in LT centers. Methods A digital questionnaire assessing vaccine policies, safety, efficacy, and center was administered online to Results Out 168 responding centers, 46.4%, 28%, 13.1%, 10.7%, 1.8% were from European, American, Western Pacific, Southeast...
Milan criteria are widely used for liver transplantation selection in hepatocellular carcinoma but have been recognized to be too restrictive. Milan-out increasingly being adopted. Our aim was analyze if waitlisted patients different outcome than patients.Retrospective study including all consecutive with admitted the waiting list between January 2012 and 2015. We included 177 patients, 146 of which eventually transplanted. Downstaging achieved cases (n = 29) before waitlisting.From...
Since 2018, our program has utilized specific psychosocial criteria and a multidisciplinary approach to assess patients for liver transplant due alcohol-associated disease (ALD), rather than the 6-month abstinence rule alone. If declined based on these criteria, recommendations are provided their providers regarding goals re-referral increase potential future candidacy. Recommendations include engagement in treatment alcohol use disorder, serial negative biomarker testing, maintenance of...