Mikel Gastaca
A5039495874- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Gallbladder and Bile Duct Disorders
- Hepatitis C virus research
- Renal cell carcinoma treatment
- Viral-associated cancers and disorders
- COVID-19 and healthcare impacts
- Neurological Complications and Syndromes
- Abdominal vascular conditions and treatments
- Pancreatitis Pathology and Treatment
- Long-Term Effects of COVID-19
- Gastric Cancer Management and Outcomes
- Hepatitis B Virus Studies
- Liver physiology and pathology
- Renal and Vascular Pathologies
- COVID-19 Clinical Research Studies
- Polyomavirus and related diseases
- Colorectal Cancer Surgical Treatments
Hospital de Cruces
2016-2025
University of the Basque Country
2016-2025
BioCruces Health research Institute
2015-2025
Chinese PLA General Hospital
2023
Chinese People's Liberation Army
2023
Moscow Clinical Scientific Center
2021
University of Hong Kong
2021
Queen Mary Hospital
2021
Sociedad Española de Trombosis y Hemostasia
2020
•The incidence of coronavirus disease 2019 (COVID-19) is higher in liver transplant patients.•Mortality rates are lower than those observed the matched general population.•Immunosuppression withdrawal may not be justified.•Mycophenolate increase risk severe COVID-19 a dose-dependent manner.•Calcineurin inhibitors and everolimus deleterious for COVID-19. Background & AimsThe outcomes immunocompromised patients matter debate.MethodsWe performed prospective nationwide study including...
Laparoscopic and robotic techniques have both been well adopted as safe options in selected patients undergoing hepatectomy. However, it is unknown whether either approach superior, especially for major hepatectomy such right or extended (RH/ERH).To compare the outcomes of vs laparoscopic RH/ERH.In this case-control study, propensity score matching analysis was performed to minimize selection bias. Patients RH/EHR at 29 international centers from 2008 2020 were included.Robotic RH/ERH.Data...
A retrospective cohort multicenter study was conducted to analyze the risk factors for tumor recurrence after liver transplantation (LT) in cirrhotic patients found have an intrahepatic cholangiocarcinoma (iCCA) on pathology examination. We also aimed ascertain whether there existed a subgroup of with single tumors ≤2 cm ("very early") which results LT can be acceptable. Twenty-nine comprised group, eight whom had "very early" iCCA (four them incidentals). The significantly associated larger...
To evaluate the outcome of patients with hepatocellular-cholangiocarcinoma (HCC-CC) or intrahepatic cholangiocarcinoma (I-CC) on pathological examination after liver transplantation for HCC.Information cirrhotic undergoing a transplant HCC and diagnosis HCC-CC I-CC by study is limited.Multicenter, retrospective, matched cohort 1:2 study.42 study; control group: 84 HCC. subgroup: 27 compared 54 controls; 15 30 controls. Patients were also divided according to preoperative tumor size number:...
Abstract Background Minimally invasive right posterior sectionectomy (RPS) is a technically challenging procedure. This study was designed to determine outcomes following robotic RPS (R-RPS) and laparoscopic (L-RPS). Methods An international multicentre retrospective analysis of patients undergoing R-RPS versus those who had purely L-RPS at 21 centres from 2010 2019 performed. Patient demographics, perioperative parameters, postoperative were analysed retrospectively central database....
Abstract More liver transplants (LT) are performed worldwide thanks to extended criteria donors (ECD). This is paralleled by a supposed increased risk of allograft failure (AF) at 90 and 365 days. study has been designed portray the LT practice investigate models AF prediction impact mitigation strategies for further improving graft patient outcomes. multicenter, international, non-competitive, observational two segment on consecutive LTs over periods (2017–2019 2022–2024). A steering...
Controlled donation after circulatory death (cDCD) has been associated with a high incidence of ischemic cholangiopathy and other perioperative complications. In an attempt to avoid these complications, we implemented active protocol cDCD liver transplant (LT) normothermic regional perfusion (NRP) preservation.This is descriptive analysis data collected from prospective date base LT preserved NRP January 2015 June 2017 minimum follow up 9 months.Fifty-seven potential donors were connected...
De novo malignancies (DNMs) following liver transplantation (LT) have been reported as 1 of the major causes late mortality, being most common cause death in second decade after LT. The overall incidence DNMs is to be range 3.1% 14.4%, and 2- 3-fold higher transplant recipients than age- sex-matched healthy controls. Long-term immunosuppressive therapy, which key maintaining host tolerance achieving good long-term outcomes, known contribute a risk DNMs. However, type DNM also depends on...
Robotic liver resections (RLR) may have the ability to address some of drawbacks laparoscopic (LLR) but few studies done a head-to-head comparison outcomes after anterolateral segment by two techniques.A retrospective study was conducted 3202 patients who underwent minimally invasive LR segments at 26 international centres from 2005 2020. Two thousand six hundred and cases met criteria which there were 358 RLR 1868 LLR cases. Perioperative compared between groups using 1:3 Propensity Score...
Abstract Background Limited liver resections (LLRs) for tumours located in the posterosuperior segments of are technically demanding procedures. This study compared outcomes robotic (R) and laparoscopic (L) LLR (IV, VII, VIII). Methods was an international multicentre retrospective analysis patients who underwent R-LLR or L-LLR at 24 centres between 2010 2019. Patient demographics, perioperative parameters, postoperative were analysed; 1 : 3 propensity score matching (PSM) coarsened exact...
To establish global benchmark outcomes indicators after laparoscopic liver resections (L-LR).There is limited published data to date on the best achievable L-LR.This a post hoc analysis of multicenter database 11,983 patients undergoing L-LR in 45 international centers 4 continents between 2015 and 2020. Three specific procedures: left lateral sectionectomy (LLS), hepatectomy (LH), right (RH) were selected represent 3 difficulty levels L-LR. Fifteen outcome cutoffs.There 3519 (LLS, LH, RH)...
Objective: To compare the outcomes of robotic limited liver resections (RLLR) versus laparoscopic (LLLR) posterosuperior segments. Background: Both and have been used for tumors in However, comparative performance safety both approaches not well examined existing literature. Methods: This is a post hoc analysis multicenter database 5,446 patients who underwent RLLR or LLLR segments (I, IVa, VII VIII) at 60 international centers between 2008 2021. Data on baseline demographics, center...
The Gender-Equity Model for liver Allocation corrected by serum sodium (GEMA-Na) and the End-stage Liver Disease 3.0 (MELD 3.0) could amend sex disparities accessing transplantation (LT). We aimed to assess these inequities in Spain compare performance of GEMA-Na MELD 3.0.
Combining simultaneously lung and liver procurement in controlled donation after circulatory death (cDCD) using normothermic abdominal perfusion (NRP) for grafts cooling rapid recovery technique (RR) the lungs increases complexity of procedure might injure grafts. A total 19 cDCDs from two centers this combined were evaluated, 16 21 transplantations performed. As controls, 34 donors brain (DBDs) included (29 41 performed). Two cDCD recipients developed primary nonfunction (12.5%). No cases...
Although good results have been reported with the use of normothermic regional perfusion (NRP) in controlled donation after circulatory death (cDCD) liver transplantation (LT), there is a lack evidence to demonstrate similar brain (DBD). We present single-center retrospective case-matched (1:2) study including 100 NRP cDCD LTs and 200 DBD median follow-up 36 months. Matching was done according donor age, recipient Model for End-Stage Liver Disease score, cold ischemia time. The following...