- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Liver Diseases and Immunity
- Alcohol Consumption and Health Effects
- Microscopic Colitis
- Gallbladder and Bile Duct Disorders
- Inflammatory Bowel Disease
- Viral gastroenteritis research and epidemiology
- Systemic Lupus Erythematosus Research
- Drug-Induced Hepatotoxicity and Protection
- Pancreatic and Hepatic Oncology Research
- Gastroesophageal reflux and treatments
- Hepatitis Viruses Studies and Epidemiology
- Lipid metabolism and biosynthesis
- Helicobacter pylori-related gastroenterology studies
- Celiac Disease Research and Management
- Clostridium difficile and Clostridium perfringens research
- Pediatric Hepatobiliary Diseases and Treatments
- Ultrasound in Clinical Applications
- Genetic and Kidney Cyst Diseases
- Diet, Metabolism, and Disease
Alessandro Manzoni Hospital
2013-2025
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2021-2024
Copenhagen University Hospital
2013-2024
Rigshospitalet
2013-2024
Cochrane
2013-2024
Avila University
2021
Presidio Ospedaliero
2020-2021
Aziende Socio Sanitarie Territoriali di Lecco
2016-2020
Ospedale Papa Giovanni XXIII
2016
University of Colorado Denver
2013
Abstract It is uncertain whether patients with nonalcoholic fatty liver disease (NAFLD) and normal alanine aminotransferase (ALT) have a milder should undergo biopsy. We reviewed the histological data of 458 Italian NAFLD in whom biopsy was indicated by altered enzymes (395 cases, 86%), or persistently elevated ferritin long-lasting severe steatosis (63 cases). Factors associated steatohepatitis (NASH) fibrosis ≥ 2 were identified multivariate analysis. Patients ALT significantly older, had...
PURPOSE: To determine the accuracy of various ultrasonographic (US) signs for assessment degree liver fibrosis, with histologic results as reference standard. MATERIALS AND METHODS: Three hundred consecutive asymptomatic patients at least 6 months increased levels aspartate aminotransferase and/or alanine underwent US and biopsy. The estimated pretest probability severe fibrosis or cirrhosis was 35%. parameters were investigated: surface nodularity, caudate lobe hypertrophy, pattern hepatic...
To analyze transient elastography-measured liver stiffness in patients with acute decompensated heart failure to describe variations measurements and assess their relationship the patients' clinical course laboratory data.This study was approved by local institutional review board, all of subjects gave verbal informed consent. Twenty-seven hospitalized no signs disease (mean age, 79 years ± 12 [standard deviation]; men [mean 78 11], 15 women 80 12]) underwent N-terminal proβ brain...
OBJECTIVES: Mucosal healing has been proposed as an important sign of the efficacy medical treatment inflammatory bowel disease; however, direct evidence in ulcerative colitis (UC) is scarce. We evaluated usefulness colonoscopy and ultrasound (US) indexes response to short-term therapy predictors subsequent outcome UC. METHODS: A total 83 patients with moderate-to-severe UC were recruited; endoscopic US severity was graded 0–3 at entry according validated scores. Of recruited patients, 74,...
The changing epidemiology of liver disease, and modifications in the recommended analytical methodology call for a re‐evaluation upper reference limits (URLs) alanine aminotransferase (ALT) levels. Using same approach consolidated 20 years ago to define healthy population, we defined URL newly International Federation Clinical Chemistry (IFCC) standardized test. In cross‐sectional study, examined 21,296 apparently blood donors (age 18‐65 years) calculated sex‐specific by 95th percentile...
OBJECTIVES: Antibiotic-associated diarrhea (AAD) andClostridium difficile-associated (CDAD) are common complications of antibiotic use. Probiotics were effective in preventing AAD and CDAD several randomized controlled trials. This study was aimed at testing the effect ofSaccharomyces boulardiion occurrence hospitalized patients. METHODS: A single-center, randomized, double-blind, placebo-controlled, parallel-group trial performed. Patients being prescribed antibiotics or on therapy for <48...
The burden of infectious diseases both before and after liver transplantation is clearly attributable to the dysfunction defensive mechanisms host, as a result cirrhosis, well use immunosuppressive agents. present document represents recommendations an expert panel commended by Italian Association for Study Liver (AISF), on prevention management complications excluding hepatitis B, D, C, HIV in setting transplantation. Due decreased response vaccinations cirrhosis within first six months...
Background The performance of pocket mobile ultrasound devices (PUDs) is comparable with that standard ultrasonography, whereas the accuracy a physical examination often poor requiring further tests to assess diagnostic hypotheses. Adding use PUD could lead an incremental benefit. Aim We assessed whether in context can reduce prescription additional when used by physicians different clinical settings. Methods conducted cohort impact study four hospital medical wards, one gastroenterological...
Changes in the Doppler waveform of hepatic veins are associated with chronic liver disease, particularly cirrhosis. We correlated abnormalities waveforms histologic findings to determine accuracy imaging detection cirrhosis.Fifty-two patients hepatitis C were examined prospectively and blindly by two sonographers. In same session, a biopsy specimen was obtained from each patient submitted three independent pathologists for conventional interpretation grading severity according predetermined...