A5004048139- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Treatments and Mutations
- Thyroid Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Liver Disease Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- Lung Cancer Research Studies
- Gallbladder and Bile Duct Disorders
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Head and Neck Anomalies
- Neuroblastoma Research and Treatments
- Cancer Treatment and Pharmacology
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Medical Imaging and Pathology Studies
- Brain Metastases and Treatment
- Peptidase Inhibition and Analysis
- Renal cell carcinoma treatment
- Cancer Diagnosis and Treatment
Carlo Forlanini Hospital
2019-2024
IRCCS San Camillo Hospital
2017-2023
Azienda Ospedaliera Sant'Andrea
2023
Ospedale generale di zona San Camillo Treviso
2023
Azienda Ospedaliera San Camillo-Forlanini
2021-2023
Ospedale Santa Maria Goretti
2010-2020
Lega Italiana per la Lotta ai Tumori
2012
Centre Hospitalier Universitaire de Besançon
2011
A multicenter analysis was conducted to evaluate the main prognostic factors driving survival after radioembolization using yttrium-90-labeled resin microspheres in patients with hepatocellular carcinoma at eight European centers. In total, 325 received a median activity of 1.6 GBq between September 2003 and December 2009, predominantly as whole-liver (45.2%) or right-lobe (38.5%) infusions. Typically, were Child-Pugh class (82.5%), had underlying cirrhosis (78.5%), good Eastern Cooperative...
Ultrasound-guided radiofrequency ablation (RFA) of solid thyroid nodules (TNs) is a minimally invasive procedure that may induce volume reduction symptomatic benign TNs.The aim the study was to evaluate effectiveness and safety RFA in debulking TNs.Eighty-four consecutive patients with cytologically were randomly assigned either single session (group A; n = 42) or follow-up B; at our center. Entry criteria nodule predominantly (with fluid component ≤ 30% volume), normal function, no...
Purpose: To compare technique efficacy and safety of laser ablation (LA) radiofrequency (RFA) in treatment benign thyroid nodules.Materials methods: Institutional review board approval was obtained, patients' consent waived. 601 nodules were treated from May 2009 to December 2014 at eight centres, 449 (309 females, age 57 ± 14 years) with LA 152 (107 RFA. A matched cohort composed 138 patients each group selected after adjustment propensity score matching. Factors influencing volume...
Objectives The decay of 90Y has a minor branch to the O+ first excited state 89Zr, de-excitation which fundamental is followed by β+–β− emission that been used recently for biodistribution assessment after selective internal radiotherapy (SIRT) treatments. purpose present study demonstrate feasibility PET imaging dose radioembolization with microspheres. Methods Activity quantification was validated through preliminary phantom studies using cylindrical body composed six inserts different...
To address the lack of prospective data on real-life clinical application trans-arterial radioembolization (TARE) in Europe, Cardiovascular and Interventional Radiological Society Europe (CIRSE) initiated observational study CIRSE Registry for SIR-Spheres® Therapy (CIRT).Patients were enrolled from 1 January 2015 till 31 December 2017. Eligible patients adult treated with TARE Y90 resin microspheres primary or metastatic liver tumours. Patients followed up 24 months after treatment, whereas...
Background: No direct prospective studies comparing laser ablation (LA) and radiofrequency (RFA) for debulking benign non-functioning thyroid nodules (BNTNs) exist. We aimed at the efficacy safety of both techniques in patients with solid or predominantly BNTN. Methods: This six-month, single-use, randomized, open-label, parallel trial compared following primary endpoints between RFA LA groups six months after treatment: (i) nodule volume reduction expressed as a percentage baseline; (ii)...
Background: Ocular melanoma (OM) metastasizes to the liver and is rapidly fatal despite aggressive therapy. Yttrium-90 microspheres (radioembolization) delivered via hepatic artery an established effective approach for primary metastatic tumors, although 90Y use in OM has not been reported previously. Methods: A retrospective review was performed all patients with who received radioembolization at 5 centers. Results: 11 12 treatments a median activity of 1.55 GBq per treatment. Toxicity...
Abstract Background Using data collected in the prospective observational study CIRSE Registry for SIR-Spheres Therapy, present aimed at identifying predictors of adverse events (AEs) following transarterial radioembolization (TARE) with Yttrium-90 resin microspheres liver tumours. Methods We analysed 1027 patients enrolled between January 2015 and December 2017 followed up 24 months. Four hundred twenty-two hepatocellular carcinoma (HCC), 120 intrahepatic (ICC), 237 colorectal metastases...
To demonstrate the feasibility of 90Y-PET imaging for biodistribution assessment after selective internal radiotherapy treatments with 90Y-microspheres, comparing results 99mTc-macroaggregated albumin (MAA) images obtained single-photon emission computed tomography.Preliminary studies were performed aim evaluating system spatial resolution and scanner sensitivity detecting annihilation photons. Subsequently, microsphere distribution was evaluated in 10 patients who underwent liver treatment....
Objective The aim of this study was to investigate the prognostic value neutrophil-to-lymphocyte ratio (NLR) and its relationship with several metabolic parameters obtained through PET in intrahepatic cholangiocarcinoma (ICC) submitted radioembolization 90 Y-microspheres ( Y-radioembolization). Methods Records 20 subjects affected by ICC Y-radioembolization were retrospectively evaluated. In all cases, pretreatment NLR carried out fluorine-18-fluorodeoxyglucose 18 F-FDG) PET/CT acquired...
The objective of our study is to evaluate the clinical outcomes and safety radiofrequency thermal ablation (RFA) for benign thyroid nodules (BTNs) over a 1-year follow-up.This monocentric retrospective study. Forty-eight patients with solid, non-functioning BTNs were treated by RFA using 17G internally cooled electrode. We categorized as small (≤ 12 mL), medium (12 30 or large (over mL). volume reduction, function, cosmetic compressive score changes side effect evaluation at 6 months...
Radioembolisation is part of the multimodal treatment hepatocellular carcinoma (HCC) at specialist liver centres. This study analysed impact prior on tolerability and survival following radioembolisation. was a retrospective analysis 325 consecutive patients with confirmed diagnosis HCC, who received radioembolisation yttrium-90 resin microspheres eight European centres between September 2003 December 2009. The decision to treat based clinical judgement multidisciplinary teams. Patients were...