A5055505106- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Thyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- BRCA gene mutations in cancer
- Neuroendocrine Tumor Research Advances
- Radiation Dose and Imaging
- Ultrasound and Hyperthermia Applications
- Genetic factors in colorectal cancer
- Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Ophthalmology and Eye Disorders
- Global Cancer Incidence and Screening
- Pituitary Gland Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Radiology practices and education
- Pancreatic function and diabetes
- Child Abuse and Related Trauma
- Heart Rate Variability and Autonomic Control
- Advanced Differential Geometry Research
- CAR-T cell therapy research
- Multiple and Secondary Primary Cancers
- Multiple Sclerosis Research Studies
A. O. Ordine Mauriziano di Torino
2015-2025
Ospedali Riuniti Umberto I
2004-2021
Policlinico Umberto I
2015-2020
University of Turin
1994-2018
Presidio Ospedaliero
2010-2012
Torino e-district
2010
Azienda Ospedaliero Universitaria San Giovanni Battista
2002
Background: Percutaneous radiofrequency thermal ablation (RTA) is a promising new therapeutic approach to manage thyroid nodules (TNs). The aim of this study was investigate the long-term effectiveness RTA in inducing shrinkage TNs as well controlling compressive symptoms and hyperfunction large series elderly subjects with solid or mainly benign TNs. Methods: Ninety-four patients cytologically were prospectively enrolled study; 66 them had nontoxic goiter 28 toxic pretoxic goiter. performed...
Benign thyroid nodules are a common clinical occurrence and usually do not require treatment unless symptomatic. During the last years, ultrasound-guided minimally invasive treatments (MIT) gained an increasing role in management of causing local symptoms. In February 2018, Italian MIT Thyroid Group was founded to create permanent cooperation between international physicians dedicated research assistance on for nodules. The group drafted this list statements based literature review consensus...
Summary Background Fine‐needle aspiration biopsy (FNAB) is the primary means to distinguish benign from malignant nodules and select patients for surgery. However, adjunctive diagnostic tests are needed because in 20–40% of cases FNAB result uncertain. Objective We investigated whether a search oncogenes RET/PTC , TRK BRAF V600E thyroid aspirates could refine an uncertain diagnosis. Patients methods A total 132 aspirates, including colloid nodules, inadequate samplings, indeterminate...
Background: Percutaneous radiofrequency thermal ablation (RFA) has been reported as an effective tool for the management of benign thyroid nodules (BTN). However, large, randomized controlled trials (RCTs) are lacking. Objective: The aims this study were to assess volume reduction BTN after a single RFA performed using moving-shot technique and compare obtained in patients treated two centers with different experience technique. Method: This was international prospective RCT. It carried out...
Background: Radiofrequency ablation (RFA) and laser (LA) are effective treatments for benign thyroid nodules. Due to their relatively recent introduction into clinical practice, there limited long-term follow-up studies. This study aimed evaluate technique efficacy, rate of regrowth, retreatment over 5 years after RFA or LA identify predictive factors outcome. Methods: In this multicenter retrospective study, the rates were evaluated in 406 patients treated with either LA, followed initial...
Abstract Context Radiofrequency ablation (RFA) of benign thyroid nodules has been gaining consensus. However, no solid information on its long-term efficacy is available. Objective To analyze the results single-session RFA. Design Retrospective longitudinal observational study. Setting Primary care center. Patients or Other Participants Adult outpatients who underwent a RFA and posttreatment follow-up least 3 years. Intervention Ultrasound-guided was performed after local anesthesia by...
Purpose: To compare technique efficacy and safety of laser ablation (LA) radiofrequency (RFA) in treatment benign thyroid nodules.Materials methods: Institutional review board approval was obtained, patients' consent waived. 601 nodules were treated from May 2009 to December 2014 at eight centres, 449 (309 females, age 57 ± 14 years) with LA 152 (107 RFA. A matched cohort composed 138 patients each group selected after adjustment propensity score matching. Factors influencing volume...
Background The purpose of this study was to confirm the generalisation radiofrequency ablation (RFA) in treatment benign thyroid nodules (BTN) and look for a correlation between final shrinkage some ultrasound (US) findings large Italian population data set. Methods This prospective included 337 patients with solid cold BTN from six institutions. Nodule volume, US pattern, function, symptom/cosmetic scores complications were evaluated before at 6 12 months. primary outcome find basal volume...
Background: One of the most widely used risk stratification systems for estimating individual patients' persistent or recurrent differentiated thyroid cancer (DTC) is American Thyroid Association (ATA) guidelines. The 2015 ATA version, which has increased number patients considered at low intermediate risk, been validated in several retrospective, single-center studies. aims this study were to evaluate real-world performance system predicting response treatment 12 months after initial and...
This guideline (GL) is aimed at providing a reference for the management of non-functioning, benign thyroid nodules causing local symptoms in adults outside pregnancy.This GL has been developed following methods described Manual National Guideline System. For each question, panel appointed by Associazione Medici Endocrinology (AME) identified potentially relevant outcomes, which were then rated their impact on therapeutic choices. Only outcomes classified as "critical" and "important"...
Radiofrequency ablation (RFA) is effective in the treatment of thyroid nodules, leading to a 50-90% reduction with respect baseline. Current guidelines indicate need for benign cytology prior RFA, though, on other side, this procedure also successfully used papillary microcarcinomas. No specific indications are available nodules an indeterminate (Bethesda III/IV).
Ten to fifteen percent of fine-needle aspiration biopsy (FNAB) thyroid nodules are indeterminate. Galectin-3 (Gal-3) and the oncogene BRAFV600E markers malignancy useful improve FNAB accuracy. The objective this study was determine whether combined analysis Gal-3 expression in aspirates could diagnosis with suspicious cytological findings. Two hundred sixty-one surgical tissues one forty-four were analyzed for presence two markers. In specimens, present 27.4% benign nodules, 91.9% papillary...
Fine-needle aspiration cytology (FNAC) is the primary means to distinguish benign thyroid nodules from malignant ones. About 20% of FNAC yields indeterminate results leading unnecessary or delayed surgery. Many studies tissue samples, majority which are retrospective advocate testing for RET rearrangements as a diagnostic adjunctive tool in with cytological findings. Because uncertain prevalence rearrangements, its utility tumor marker still controversial. The goal this study was establish...
Benign thyroid nodules display a broad range of behaviors from stationary size to progressive growth. The RET/PTC oncogene has been documented in fraction benign nodules, besides papillary carcinomas, and it might therefore influence their growth.The aim the present work was evaluate whether associates with different nodular growth rate.In this prospective multicentric study, 125 subjects were included. RET rearrangements analyzed cytology samples; clinical ultrasonographic nodule...
Laser ablation is a therapeutic modality used to reduce the volume of large benign thyroid nodules. Unsatisfactory reduction and regrowth are observed in some treated The aim study was evaluate long-term outcomes laser treatment for solid nodules during 5-year follow-up period, rate, predictive risk factors nodule regrowth.We retrospectively evaluated patients with benign, solid, cold who underwent were followed-up 5 years. According selection criteria, 104 included (median baseline volume,...
Abstract Context The risk stratification of patients with differentiated thyroid cancer (DTC) is crucial in clinical decision making. most widely accepted method to assess recurrent/persistent disease described the 2015 American Thyroid Association (ATA) guidelines. However, recent research has focused on inclusion novel features or questioned relevance currently included features. Objective To develop a comprehensive data-driven model predict persistent/recurrent that can capture all...