A5067621786- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging and Pathology Studies
- Neuroendocrine Tumor Research Advances
- Radiation Detection and Scintillator Technologies
- Cardiac Imaging and Diagnostics
- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Monoclonal and Polyclonal Antibodies Research
- Lymphoma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Breast Lesions and Carcinomas
- Nuclear Physics and Applications
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced X-ray and CT Imaging
- Cancer Immunotherapy and Biomarkers
- Cardiovascular Function and Risk Factors
- Peptidase Inhibition and Analysis
- Pancreatic and Hepatic Oncology Research
- Neuropeptides and Animal Physiology
Sapienza University of Rome
2010-2020
CTO Andrea Alesini
2008-2019
University of Cologne
2016
Istituto Neurologico Mediterraneo
2016
RWTH Aachen University
2016
Ludwig-Maximilians-Universität München
2016
University of Lausanne
2016
Forschungszentrum Jülich
2016
Azienda Ospedaliera Sant'Andrea
2009-2015
Azienda Ospedaliera Ospedale Civile di Legnano
2013
Objectives The decay of 90Y has a minor branch to the O+ first excited state 89Zr, de-excitation which fundamental is followed by β+–β− emission that been used recently for biodistribution assessment after selective internal radiotherapy (SIRT) treatments. purpose present study demonstrate feasibility PET imaging dose radioembolization with microspheres. Methods Activity quantification was validated through preliminary phantom studies using cylindrical body composed six inserts different...
White blood cell (WBC) scintigraphy is considered the nuclear medicine imaging gold standard for diagnosing osteomyelitis in diabetic foot. Recent papers have suggested that use of (18)F-FDG PET/CT produces similar diagnostic accuracy, but clear interpretation criteria not yet been established. Our aim was to evaluate role sequential patients with a high suspicion define objective be compared WBC scintigraphy.Thirteen whom clinicians positive (7 ulcers, 6 exposed bone) were enrolled. The...
Background —Somatostatin receptor scintigraphy (SRS) and octreotide therapy have both changed the management of gastroenteropancreatic endocrine tumours, but very few data are available on use SRS to visualise treat somatostatinomas. Method —The results treatment in three somatostatinoma patients were examined. Results —SRS was able detect extensive hepatic involvement patient 1, one pancreatic lesion 2, 3. Octreotide (0.5 mg/day subcutaneously) effective decreasing plasma levels...
Objective To study human myocardial ultrastructural changes after carbon monoxide (CO) poisoning inducing reversible cardiac failure. Design Case report: clinical, functional and morphologic findings. Settings Public university-affiliated hospital electron microscopy laboratory. Patient A 25-yr-old woman with evidence of failure acute CO poisoning. Interventions Hyperbaric intensive care treatment over 10 days. Scintigraphic angiography endomyocardial biopsy. Measurements Main Results...
Gamma ray imaging is usually accomplished by the use of a relatively large scintillating crystal coupled to either number photomultipliers (PMTs) (Anger Camera) or single Position Sensitive PMT (PSPMT). Recently development new diagnostic techniques, such as scintimammography and radio-guided surgery, have highlighted significant limitations Anger camera in procedures. In this paper dedicated gamma proposed for clinical applications with aim improving image quality utilizing detectors an...
The rationale of the present study was to radiolabel rituximab with 99m-technetium and image B lymphocytes infiltration in affected tissues patients chronic inflammatory autoimmune diseases, particular, candidates be treated unlabelled rituximab, order provide a for ‘evidence-based’ therapy. Rituximab labelled 99mTc via 2-ME reduction method. In vitro quality controls 99mTc-rituximab included stability assay, cysteine challenge, SDS-PAGE, immunoreactive fraction assay competitive binding on...
Abstract Background The role of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in the diagnostic algorithm entero-pancreatic neuroendocrine neoplasms (EP NENs) is unclear because most available data derive from heterogeneous populations terms tumor biology and disease status at time examination. aim this study was to determine ability 18F-FDG PET identify patients with more aggressive among those advanced EP NENs. Subjects, Materials, Methods . Patients NENs known...
To demonstrate the feasibility of 90Y-PET imaging for biodistribution assessment after selective internal radiotherapy treatments with 90Y-microspheres, comparing results 99mTc-macroaggregated albumin (MAA) images obtained single-photon emission computed tomography.Preliminary studies were performed aim evaluating system spatial resolution and scanner sensitivity detecting annihilation photons. Subsequently, microsphere distribution was evaluated in 10 patients who underwent liver treatment....
The evolution of radiation necrosis (RN) varies depending on the combination radionecrotic tissue and active tumor cells. In this study, we characterized long-term metabolic RN by sequential PET/CT imaging with 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (F-DOPA) in patients brain metastases following stereotactic radiosurgery (SRS).Thirty consecutive 34 suspected SRS repeated F-DOPA every 6 months or yearly addition to standard MRI monitoring. Diagnoses local progression (LP) were...