A5060268557- Medical Imaging Techniques and Applications
- Neurological disorders and treatments
- Radiopharmaceutical Chemistry and Applications
- Parkinson's Disease Mechanisms and Treatments
- Prostate Cancer Treatment and Research
- Glioma Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Radiomics and Machine Learning in Medical Imaging
- Cardiovascular Function and Risk Factors
- Neuroendocrine Tumor Research Advances
- Medical Imaging and Pathology Studies
- Colorectal Cancer Surgical Treatments
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Metabolism, Diabetes, and Cancer
- AI in cancer detection
- Mitochondrial Function and Pathology
- Biomedical Text Mining and Ontologies
- Neuroblastoma Research and Treatments
- Glycogen Storage Diseases and Myoclonus
- Diabetes Treatment and Management
- Functional Brain Connectivity Studies
Magna Graecia University
2016-2025
Azienda Ospedaliero Universitario Mater Domini
2020-2024
Park University
2022
Magna (Austria)
2010
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2005-2009
Tumour Institute of Tuscany
2005-2006
University of Campania "Luigi Vanvitelli"
2006
National Cancer Institute
2004
University of Naples Federico II
1999
Alterations in myocardial mechano-energetic efficiency (MEEi), which represents the capability of left ventricles to convert chemical energy obtained by oxidative metabolism into mechanical work, have been associated with cardiovascular disease. Although whole-body insulin resistance has related impaired MEEi, it is unknown relationship between cardiac and MEEi. Aim this study was evaluate insulin-stimulated glucose metabolic rate (MrGlu) MEEi subjects having different degrees tolerance.We...
Motor phenotypes of Parkinson's disease (PD) are recognized to have different prognosis and therapeutic response, but the neural basis for this clinical heterogeneity remains largely unknown.The main aim study was compare differences in structural connectivity metrics motor network between tremor-dominant nontremor PD (TD-PD NT-PD, respectively) using probabilistic tractography-based analysis.A total 63 patients (35 TD-PD 28 NT-PD patients) 30 healthy controls underwent a 3 T MRI.Next,...
Abstract Metabolic associated fatty liver disease (MAFLD), commonly known as non-alcoholic disease, represents a continuum of events characterized by excessive hepatic fat accumulation which can progress to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and in some severe cases hepatocellular carcinoma. MAFLD might be considered multisystem that affects not only the but involves wider implications, relating several organs systems, brain included. The present study aims investigate...
Abstract The cooccurrence of rest and postural tremor (mixed tremor) as the predominant clinical manifestation in patients who do not fulfill diagnostic established criteria for essential (ET) or Parkinson's disease (PD) poses a challenge. Twenty‐two with mixed additional mild extrapyramidal features, such bradykinesia rigidity, 20 probable PD, 10 ET, 18 controls were investigated through combined use dopamine transporter 123 I‐FP‐CIT‐single‐photon emission tomography (DAT‐SPECT) cardiac...
ABSTRACT Background Idiopathic normal pressure hydrocephalus and PSP share several clinical radiological features, making differential diagnosis, at times, challenging. Objectives To differentiate idiopathic from using MR volumetric linear measurements. Methods Twenty‐seven patients, 103 probable 43 control subjects were consecutively enrolled. Automated ventricular volumetry was performed Freesurfer 6 on T 1 ‐weighted images. Linear measurements, such as callosal angle a new measure, termed...
Impaired insulin-stimulated myocardial glucose uptake has occurred in patients with type 2 diabetes or without coronary artery disease. Whether cardiac insulin resistance is present remains uncertain subjects at risk for diabetes, such as individuals impaired tolerance (IGT) those normal (NGT) and 1-h postload ≥155 mg/dL during an oral test (NGT high). This issue was examined this study.The metabolic rate of (MRGlu) measured by using dynamic 18F-fluorodeoxyglucose positron emission...
Introduction Differential diagnosis of rest tremor (RT) disorders is challenging, often requiring 123I-ioflupane single-photon-emission-computed tomography (DaTscan), an expensive technique not available worldwide. In the current study, we investigated performance a new wearable mobile device termed “RT-ring” in predicting DaTscan result patients presenting with RT based on inertial features. Methods Consecutive underwent RT-ring analysis, surface electromyography (sEMG), and DaTscan. The...
The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly the context Radiotherapy (RT) treatment planning. use sCT enables calculation doses, pushing towards Magnetic Resonance Imaging (MRI) guided radiotherapy treatments. Moreover, with introduction MRI-Positron Emission (PET) hybrid scanners, derivation from MRI can improve attenuation correction PET images. Deep learning methods for MRI-to-sCT have shown...
ABSTRACT Imaging measurements, such as the ratio of midsagittal areas midbrain and pons (midbrain/pons) Magnetic Resonance Parkinsonism Index (MRPI), have been proposed to differentiate progressive supranuclear palsy (PSP) from Parkinson's disease (PD). However, abnormal midbrain/pons values suggestive PSP also reported in elderly individuals patients with PD. We investigated effect aging on single or combined imaging measurements brainstem. calculated MRPI (the multiplied by middle...
The importance of copper in the metabolism cancer cells has been widely studied last 20 years and a clear-cut association between levels deregulation established. Copper-64, emitting positrons β-radiations, is indicated for labeling large number molecules suitable radionuclide imaging as well therapy. Glioblastoma multiforme (GBM) CNS tumor with worse prognosis, characterized by high recurrences strong resistance to chemo-radio therapy, strongly affecting patients survival. We have recently...