A5019279044- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Genetic Neurodegenerative Diseases
- Vestibular and auditory disorders
- Alzheimer's disease research and treatments
- Action Observation and Synchronization
- Neurological and metabolic disorders
- Anaerobic Digestion and Biogas Production
- Motor Control and Adaptation
- Cerebrovascular and Carotid Artery Diseases
- Cerebral Palsy and Movement Disorders
- Acute Ischemic Stroke Management
- Human Health and Disease
- Dementia and Cognitive Impairment Research
- Neurological Disease Mechanisms and Treatments
- Neural dynamics and brain function
- Odor and Emission Control Technologies
- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- Cancer, Lipids, and Metabolism
- Medical Imaging Techniques and Applications
- Amyotrophic Lateral Sclerosis Research
- Peripheral Neuropathies and Disorders
Politecnico di Milano
2023
National Research Council
2012-2022
Institute of Molecular Bioimaging and Physiology
2014-2022
University of Trento
2013
Institute of Neurological Sciences
2012
Essential tremor is a common neurological disorder characterized by motor and cognitive symptoms including working memory deficits. Epidemiological research has shown that patients with essential are at higher risk to develop dementia relative age-matched individuals; this demonstrates impairments reflect specific, although poorly understood, disease mechanisms. Neurodegeneration of the cerebellum been implicated in pathophysiology itself; however, whether cerebellar dysfunctions relate...
Monitoring of the intracellular concentrations Cl(-) and H(+) requires sensitive probes that allow reliable quantitative measurements without perturbation cell functioning. For these purposes most promising are genetically encoded fluorescent biosensors, which have become powerful tools for non-invasive monitoring ions, molecules, enzymatic activity. A ratiometric CFP/YFP-based construct with a relatively good sensitivity to has been developed (Markova et al., 2008; Waseem 2010). Recently,...
Background: Major depression (MD) is a common psychiatric disorder in multiple sclerosis (MS). Despite the negative impact of MD on quality life MS patients, little known about its underlying brain mechanisms. Objective: We studied whole-brain connectivity patterns that were associated with MS. Alterations mainly expected within limbic circuits. Methods: Diffusion tensor imaging data collected 20 patients MD, 22 non-depressed and 16 healthy controls. used deterministic tractography graph...
ABSTRACT Imaging measurements, such as the ratio of midsagittal areas midbrain and pons (midbrain/pons) Magnetic Resonance Parkinsonism Index (MRPI), have been proposed to differentiate progressive supranuclear palsy (PSP) from Parkinson's disease (PD). However, abnormal midbrain/pons values suggestive PSP also reported in elderly individuals patients with PD. We investigated effect aging on single or combined imaging measurements brainstem. calculated MRPI (the multiplied by middle...
Although measurement of total hippocampal volume is considered as an important hallmark Alzheimer's disease (AD), recent evidence demonstrated that atrophies subregions might be more sensitive in predicting this neurodegenerative disease. The vast majority neuroimaging papers investigating topic are focused on the difference between AD and patients with mild cognitive impairment (MCI), not considering impact MCI who will or convert AD. For reason, aim study was to determine if measurements...
Objective Chefs exert expert motor and cognitive performances on a daily basis. Neuroimaging has clearly shown that long-term skill learning (i.e., athletes, musicians, chess player or sommeliers) induces plastic changes in the brain thus enabling tasks to be performed faster more accurately. How chef's expertise is embodied specific neural network never been investigated. Methods Eleven Italian head chefs with brigade management 11 demographically-/ psychologically- matched non-experts...