A5018933113- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Radiation Detection and Scintillator Technologies
- Prostate Cancer Treatment and Research
- Cardiac Imaging and Diagnostics
- Nuclear Physics and Applications
- Medical Imaging and Pathology Studies
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Bone health and treatments
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Digital Radiography and Breast Imaging
- Atomic and Subatomic Physics Research
- Neuropeptides and Animal Physiology
- Cardiac pacing and defibrillation studies
- Breast Lesions and Carcinomas
- Adrenal and Paraganglionic Tumors
- Neurological disorders and treatments
- Neuroendocrine Tumor Research Advances
- Pituitary Gland Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Parkinson's Disease Mechanisms and Treatments
Sapienza University of Rome
2016-2025
Policlinico Umberto I
1996-2025
Istituto Nazionale di Fisica Nucleare
2011
Istituto Nazionale di Fisica Nucleare, Sezione di Bologna
2009
University of Bologna
2009
National Agency for New Technologies, Energy and Sustainable Economic Development
2009
Istituto Nazionale di Fisica Nucleare, Sezione di Padova
2009
University of Rome Tor Vergata
1991-2006
Institute of Biomedical Technologies
1999-2002
University of Ferrara
2000-2002
Biocompatible gold nanoparticles (AuNPs) are particularly interesting for photo-thermal therapy (PTT) of cancer treatment because their ability to convert light into heating efficiently. Nevertheless, the random accumulation AuNPs in tissues, mainly determined by retention time bloodstream, is one main limiting factors use PTT applications. For this reason, efficient targeting and monitoring selected tissues paramount importance. This manuscript reports on a new generation 99mTc-labeled...
Abstract Purpose To combine peripheral blood indices and clinical factors in a prognostic score for metastatic castration-resistant prostate cancer (mCRPC) patients treated with radium-223 dichloride ([ 223 Ra]RaCl 2 ). Patients methods Baseline neutrophil-to-lymphocyte ratio (NLR), derived NLR (donor), lymphocyte-to-monocyte (LMR), platelet-to-lymphocyte (PLR), systemic inflammation index (SII), Eastern Cooperative Oncology Group performance status (ECOG PS), Gleason (GS) group, number of...
Purpose Coronary artery disease (CAD) underestimation represents a major pitfall of single-photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI). calcium score (CACS) has emerged as sensitive tool for the assessment suspect CAD; however, integration SPECT-MPI with CACS been seldom evaluated, so far, and was therefore aim present study. Methods Patients undergoing subsequent coronary angiography were included. ROC curves used to identify values best predictive CAD. In...
Background/Objectives: The prognostic value of baseline clinical parameters in predicting the survival prolonging effect Radium-223-dichloride (223RaCl2) for metastatic castration resistant prostate cancer (mCRPC) patients has been object intensive research and remains an open issue. This national multicenter study aimed to corroborate evidence ten years experience with 223RaCl2 by collecting data from eight Italian Nuclear Medicine Units. Methods: Data 581 consecutive mCRPC treated were...
Background/Objectives: Hereditary transthyretin-mediated amyloidosis (ATTRv) is a rare disease characterized by the deposition of amyloid in heart and peripheral nerves, particularly affecting small fibers. This study aims to evaluate autonomic cardiac involvement ATTRv. Methods: Twelve patients with ATTRv twelve sex- age-matched healthy subjects underwent 123I-mIBG scintigraphy early late heart-to-mediastinum ratio (eH/M lH/M), 99mTc-HDP bone scan scintigraphy, neurophysiological...
To investigate the effects of radical radiotherapy (RT) relevant interruptions (RRI), single (sRRI) or multiple (mRRI), on Biochemical Failure-Free Survival (BFFS), Metastases-Free (MFS) and Overall (OS) in prostate cancer (PCa) patients. We conducted a retrospective analysis involving 383 patients diagnosed with who received RT between March 2013 April 2021, doses ranging from 60 to 80 Gy (median dose 76.0 Gy), either alone combination androgen deprivation therapy. The study aimed evaluate...
Gamma ray imaging is usually accomplished by the use of a relatively large scintillating crystal coupled to either number photomultipliers (PMTs) (Anger Camera) or single Position Sensitive PMT (PSPMT). Recently development new diagnostic techniques, such as scintimammography and radio-guided surgery, have highlighted significant limitations Anger camera in procedures. In this paper dedicated gamma proposed for clinical applications with aim improving image quality utilizing detectors an...