Pasquale Lepiane
A5037244830- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- COVID-19 and healthcare impacts
- Appendicitis Diagnosis and Management
- Pancreatitis Pathology and Treatment
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Screening and Detection
- Diverticular Disease and Complications
- Hernia repair and management
- Metastasis and carcinoma case studies
- Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Sarcoma Diagnosis and Treatment
- Stoma care and complications
- Liver physiology and pathology
- Gastrointestinal Tumor Research and Treatment
- Abdominal Surgery and Complications
- Hepatitis B Virus Studies
- Pelvic floor disorders treatments
Ospedale San Paolo
2021-2025
Civita
2021-2025
University of Ferrara
2024
Royal London Hospital
2024
University College London
2024
Collaborative Group (United States)
2021-2023
University of Turin
2021
IRCCS San Camillo Hospital
2008-2019
Carlo Forlanini Hospital
2014-2017
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
2008-2015
Abstract Background The aims of this study were to define the clinicopathological features and prognosis gastric cancer in young European adults. Methods Between 1990 2004, 603 patients with enrolled a prospective database. findings for 51 (8·5 per cent) aged 45 years or less compared those 457 between 46 75 years. Results In younger group there significantly more women (57 versus 36·3 cent; P = 0·004), Laurén diffuse-type carcinomas (73 42·7 < 0·001), N2–3 lymph node metastases (59...
In locally advanced gastric carcinoma infiltrating adjacent organs, an extended resection including invaded organs is required to improve the prognosis. We retrospectively analyzed our experience with multiorgan (EMR) in patients cancer.Between December 1979 and April 2004, 65 were resected for macroscopically invading other organs. Various clinicopathologic factors influencing early late results evaluated. Survival rates calculated according Kaplan-Meier method. Prognostic evaluated by...
The choice of whether to perform protective ileostomy (PI) after anterior resection (AR) is mainly guided by risk factors (RFs) responsible for the development anastomotic leakage (AL). However, clear guidelines about PI creation are still lacking in literature and this often decided according surgeon's preferences, experiences or feelings. This qualitative study aims investigate, an open-ended question survey, individual decision-making process regarding elective AR.Fifty four colorectal...
Abstract Background This multicentre case–control study aimed to identify risk factors associated with non-operative treatment failure for patients CT scan Hinchey Ib-IIb and WSES Ib-IIa diverticular abscesses. Methods included a cohort of adult experiencing their first episode CT-diagnosed abscess, all whom underwent initial comprising either antibiotics alone or in combination percutaneous drainage. The was stratified based on the outcome treatment, specifically identifying those who...
Abstract Background The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during COVID-19 pandemic. aim ChoCO-W study to compare clinical findings outcomes acute in patients who had disease with those did not. Methods Data were prospectively collected over 6 months (October 1, 2020, April 30, 2021) 1-month follow-up. In October Delta variant SARS CoV-2 isolated for first time. Demographic data analyzed reported according STROBE...
The use of cadaveric vein allografts was first described by our group as a feasible option for venous reconstruction. aim this study to report long-term results innovative technique.Cold-stored veins harvested from donor cadavers were used homologous grafts reconstruction after vascular resection during pancreaticoduodenectomy. Surgical technique included patch closure or segmental interposition. Graft patency assessed computed tomography postoperatively and follow-up. Postoperative...
Major surgical societies advised using non-operative management of appendicitis and suggested against laparoscopy during the COVID-19 pandemic. The hypothesis is that a significant reduction in number emergent appendectomies was observed pandemic, restricted to complex cases. study aimed analyse pandemic on national basis compare it same period previous year. This multicentre, retrospective, observational investigating outcomes patients undergoing appendectomy March-April 2019 vs 2020....
Hepatocellular carcinoma (HCC) with or without underlying liver disease can be treated by surgical resection. The aim of this study was to evaluate the feasibility, morbidity and mortality a laparoscopic approach in cirrhotic patients HCC.From 2004 September 2014, 90 underwent resection (LLR) for HCC. Data were collected prospectively maintained database since 2001. Preoperative patient evaluation based on multidisciplinary team meeting assessment.Median age 63 years; 67 (74.4%) male. Median...
Management of hepatocellular carcinoma (HCC) larger than 5 cm is still debated. The aim our study was to compare morbidity and mortality after the surgical resection HCC according nodule size.Since 2001, 429 liver resections for were performed in institution. We divided cohort into two groups, 88 patients group 1 with diameter from 10 39 2 ≥10 cm.In 30.7% cases first 35.9% second grew a healthy liver. A major 36.3% vs. 66.6% (P=0.001). In ten laparoscopic approach performed. Median operative...
Yttrium-90 microspheres radioembolization has shown to be an effective modality of treatment in patients with primary or metastatic liver tumours [1][2][3][4].It is usually offered advanced cancers.However, surgical experience after very limited anecdotal cases mainly related hepatocellular carcinoma.We have treated carcinoma metastasis from colon, breast, melanoma and neuroendocrine tumours.In our such we were able downstage the tumour surgery only case carcinoma.Five had transplantation 1...