Nan Zhang

ORCID: 0000-0001-6154-0383
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About
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Research Areas
  • Asthma and respiratory diseases
  • Sinusitis and nasal conditions
  • Lung Cancer Treatments and Mutations
  • Allergic Rhinitis and Sensitization
  • Gastric Cancer Management and Outcomes
  • Cancer survivorship and care
  • Lung Cancer Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Colorectal and Anal Carcinomas
  • Colorectal Cancer Treatments and Studies
  • Endometrial and Cervical Cancer Treatments
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Ferroptosis and cancer prognosis
  • Respiratory and Cough-Related Research
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Screening and Detection
  • Esophageal Cancer Research and Treatment
  • Metastasis and carcinoma case studies
  • Colorectal Cancer Surgical Treatments
  • Cancer Genomics and Diagnostics
  • Immune cells in cancer
  • Sarcoma Diagnosis and Treatment
  • Digital Mental Health Interventions
  • Cancer Mechanisms and Therapy
  • Medical Research and Treatments

Shanghai Jiao Tong University
2020-2024

Hebei Medical University
2023-2024

Fourth Hospital of Hebei Medical University
2023-2024

Mayo Clinic in Arizona
2024

Ruijin Hospital
2019-2024

Chongqing University
2024

Grail (United States)
2024

Menlo School
2024

Chongqing Cancer Hospital
2024

Sun Yat-sen University
2006-2023

// Kaiyan Chen 1, 2, * , Guoping Cheng 3, Fanrong Zhang 1 Nan Dan Li 2 Jiaoyue Jin Junzhou Wu Lisha Ying Weimin Mao Su Cancer Research Institute, Zhejiang Hospital and Key Laboratory Diagnosis Treatment Technology on Thoracic Oncology of Province, Hangzhou, China Department Oncology, The Second Clinical Medical College Chinese University, 3 Pathology, Hospital, These authors contributed equally to this work Correspondence to: Su, email: sudan@zjcc.org.cn Mao, maowm1218@163.com Keywords:...

10.18632/oncotarget.8956 article EN Oncotarget 2016-04-23

Acute myeloid leukemia (AML) is a clonal malignant proliferative blood disorder with poor prognosis. Ferroptosis, novel form of programmed cell death, holds great promise for oncology treatment, and has been demonstrated to interfere the development various diseases. A range genes are involved in regulating ferroptosis can serve as markers it. Nevertheless, prognostic significance these AML remains poorly understood. Transcriptomic clinical data patients were acquired from The Cancer Genome...

10.3389/fgene.2021.708699 article EN cc-by Frontiers in Genetics 2022-01-17

Background This study analyzes the impact of Staphylococcus aureus enterotoxins (SAEs) and inflammatory pattern in polyps from China. Methods Nasal tissue was obtained 27 consecutive bilateral nasal 15 control patients assayed for eotaxin, interleukin-5, soluble interleukin-2 receptor, transforming growth factor (TGF) β 1 , myeloperoxidase, eosinophil cationic protein, total IgE, specific IgE to SAEs. Activated eosinophils were stained using EG2 antibodies Chinese comparative white patients....

10.2500/ajr.2006.20.2887 article EN American Journal of Rhinology 2006-07-01

Hashimoto's thyroiditis, also known as chronic lymphocytic is a common autoimmune which mostly occurs in young and middle-aged women. It can be manifested hyperthyroidism the early stage; hypothyroidism may appear with progression of disease. Studies have shown that multiple factors such heredity, environment, autoimmunity are involved pathogenesis, but specific mechanism not clear. In our study, we tried to find key genes potential molecular mechanisms thyroiditis provide new ideas for...

10.1155/2021/8263829 article EN cc-by Journal of Immunology Research 2021-08-28

Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels periostin and tenascin C CRSwNPs, but whether they are associated dysregulation unknown. Therefore, present study aimed to investigate regulatory roles these two ECM proteins expression polyps.The concentrations MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, TIMP-1, TIMP-2, TIMP-3, TIMP-4, periostin, tissue homogenates 51...

10.1002/clt2.12059 article EN cc-by Clinical and Translational Allergy 2021-09-01

Cervical cancer is the fourth most prevalent in women, which decreases quality of life patients. Traditional interventions have failed to improve overall survival period patients due high tumor recurrence after treatment or late diagnosis. Fortunately, preliminary evidence suggests that anti-angiogenic and immunotherapy can efficiently treat against cervical cancer. However, there no clear on efficacy Therefore, this study, we classified cancers TCGA dataset using various algorithms explored...

10.3389/fcell.2021.573497 article EN cc-by Frontiers in Cell and Developmental Biology 2021-04-09

There are currently an increasing number of mobile health (mHealth) programs offered to patients with breast cancer undergoing chemotherapy, but their rate adherence app usage has remained low. This study aimed examine the feasibility mHealth app-based program such as and determine preliminary effects on self-efficacy, quality life, symptom burden healthcare utilization in these patients.

10.1177/20552076241231560 article EN cc-by-nc-nd Digital Health 2024-01-01

Background Microwave ablation (MWA) has recently become an established treatment option for topical therapy of lung cancer patients. In this study, we evaluated whether MWA combined with chemotherapy could improve progression‐free survival (PFS) patients stage IV adenocarcinoma compared alone. Methods A total 49 were enrolled into the study; 21 accepted chemotherapy, 28 only chemotherapy. Enumeration data analyzed using χ2 test or Fisher's exact probability and univariate analysis was...

10.1111/1759-7714.13129 article EN cc-by-nc-nd Thoracic Cancer 2019-06-27

Background/Aims: Malignant mesothelioma of the tunica vaginalis testis is a rare and lethal disease. The genomic characteristics genetic changes tumor cells during progression this disease are unknown. Methods: we performed whole-genome sequencing four successive samples derived from surgery blood sample in single patient. Results: All tumors were found to have significant C-to-T T-to-C mutations, amplification copy number chromosomes 1 12 notified all samples. Subclone analysis revealed...

10.1159/000486355 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2018-01-01
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