Laura Scardamaglia

ORCID: 0000-0001-6160-8886
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About
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Research Areas
  • Autoimmune Bullous Skin Diseases
  • Urticaria and Related Conditions
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Dermatological and Skeletal Disorders
  • Genetic and rare skin diseases.
  • Cutaneous lymphoproliferative disorders research
  • Platelet Disorders and Treatments
  • Vascular Malformations and Hemangiomas
  • Autoimmune and Inflammatory Disorders
  • Cutaneous Melanoma Detection and Management
  • Drug-Induced Adverse Reactions
  • Cancer and Skin Lesions
  • Nonmelanoma Skin Cancer Studies
  • Cytomegalovirus and herpesvirus research
  • Herpesvirus Infections and Treatments
  • Eosinophilic Disorders and Syndromes
  • Skin and Cellular Biology Research
  • Dermatology and Skin Diseases
  • Tumors and Oncological Cases
  • Allergic Rhinitis and Sensitization
  • Vasculitis and related conditions
  • Contact Dermatitis and Allergies
  • Viral-associated cancers and disorders
  • Vascular Tumors and Angiosarcomas
  • Inflammatory Myopathies and Dermatomyositis

The University of Melbourne
2015-2025

The Royal Melbourne Hospital
2015-2025

Royal Children's Hospital
2015-2025

Footscray Hospital
2021-2025

Western Health
2021-2025

Universities UK
2022

Murdoch Children's Research Institute
2022

Western Hospital
2015

Skin and Cancer Foundation
2003

Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some early intervention. The Australasian Vascular Anomalies Network and the Paediatric Dermatology have developed consensus statement for with oral propranolol. Infants that are life threatening, at risk ulceration, or causing significant functional impairment, psychological impact physical deformity should be treated Oral propranolol is safe effective in healthy infants can...

10.1111/ajd.12600 article EN Australasian Journal of Dermatology 2017-03-01

ABSTRACT Since the concurrence of bullous pemphigoid (BP) and psoriasis was first reported in 1929, an increasing number studies has been published to analyse their relationship recent years. However, pathogenesis is not yet well understood, coexistence two conditions imposes a difficult therapeutic challenge. This case report demonstrates secukinumab achieving dramatic clinical improvement both chronic active BP.

10.1111/ajd.13803 article EN Australasian Journal of Dermatology 2022-02-09

Granulomatosis with polyangiitis (GPA) is a small-to-medium vessel vasculitis that can affect the skin, respiratory tract, kidneys and other organs. A rare cutaneous manifestation of GPA pyoderma gangrenosum (PG)-like ulcerations, which have debilitating disfiguring consequences. We report case man in his 40s refractory PG-like ulcerations secondary to GPA, not responsive conventional immunosuppression, who was successfully treated rituximab. This emphasises need for early recognition this...

10.1136/bcr-2024-262584 article EN BMJ Case Reports 2025-01-01

ABSTRACT Cutaneous arteriovenous haemangioma (AVH) is a rare benign vascular lesion, which typically occurs on the head and neck. Its aetiology unclear but thrombosis, trauma, infection or endocrine triggers have been proposed. We report case of 64‐year‐old female presenting with acquired AVH upper lip following oral herpes simplex virus infection. This first documented occurrence as post‐herpetic isotopic response (PHIR).

10.1111/ajd.14421 article EN Australasian Journal of Dermatology 2025-01-25

A 64-year-old male was admitted to hospital for relapsed schizophrenia. He referred the dermatology unit widespread scaly plaques. Minimal history obtained from patient due poor engagement with treating clinicians. collateral revealed 8 weeks of mental health decline, characterised by paranoia, social withdrawal, oral intake and self-neglect. The skin lesions had been present weeks, but not sought any treatment this. Diarrhoea unknown duration also noted. His significant schizophrenia,...

10.1111/ajd.14438 article EN Australasian Journal of Dermatology 2025-02-22

ABSTRACT We present a case series of six patients with co‐existing oral pemphigus vulgaris and lichen planus to further characterize the relationship between these two conditions. The findings suggest that represent distinct

10.1111/ajd.14462 article EN Australasian Journal of Dermatology 2025-03-24

Dietary triggers are well-recognised contributors to orofacial granulomatosis. As such, a cinnamon- and benzoate-free diet is often suggested as first-line management. We report novel case of granulomatosis secondary sodium metabisulfite, which was identified through patch testing.

10.1093/bjd/ljaf132 article EN British Journal of Dermatology 2025-04-09

SUMMARY The results of patch testing to compound tincture benzoin in 477 patients performed at the Contact Dermatitis Clinic Skin and Cancer Foundation Melbourne during 1999 are presented. There have been fewer than 30 reported cases contact allergy from benzoin, none last decade. Our showed 45 out had a positive reaction which was third most common allergen our series. Of these patients, 14 strong reactions, but only two definitely recalled exposure were clinically relevant. Twenty‐eight...

10.1046/j.1440-0960.2003.00674.x article EN Australasian Journal of Dermatology 2003-07-23

SUMMARY A 9‐year‐old girl with incontinentia pigmenti (IP) diagnosed soon after birth subsequently developed 20‐nail dystrophy at the age of 3 years. This persists unchanged 6 years later, and she has no other evidence any cutaneous disease, nor a family history IP or nail dystrophy. Twenty‐nail been associated number diseases including eczema, lichen planus, alopecia areata psoriasis congenital associations, but association appears to be unique.

10.1046/j.1440-0960.2003.00642.x article EN Australasian Journal of Dermatology 2003-02-01

Pemphigus is an autoimmune B-cell mediated blistering disease associated with significant morbidity and mortality. Rituximab has proven effective for the treatment of steroid-refractory pemphigus, although there controversy over optimum dosing protocol. Additionally, control often requires long-term immunosuppression, even in disease-free periods. We present a case series single-centre follow up nine patients treated two 500-mg doses rituximab separated by 14 days along concurrent adjuvant...

10.1111/ajd.12571 article EN Australasian Journal of Dermatology 2017-02-17

Abstract Objectives To identify factors which influence the intraoral prevalence of human herpes viruses (HHVs) using mucosal swabs, saliva samples and qPCR analysis. Methodology In this cross‐sectional observational study, matched oral swabs were collected from a total 115 subjects: 70 immunocompetent subjects with no abnormalities, 22 abnormalities 23 therapeutically immunocompromised individuals. Extracted DNA was analysed by multiplex for detection quantification HHVs 1–6. Results At...

10.1111/odi.13523 article EN Oral Diseases 2020-07-01

We report a case of 42-year-old woman (Gravida 1, Para 1) who presented in her third trimester pregnancy with photo distributed eruption and arthralgias was subsequently diagnosed dermatomyositis. She had an emergency Caesarean section at 34 weeks plus 6 days gestation due to decreased fetal movements non-reassuring heart rate. Her placenta sent for histopathology showed features massive perivillous fibrin deposition. To our knowledge, this is the first MDA-5 positive dermatomyositis live delivery.

10.1111/jog.15625 article EN Journal of Obstetrics and Gynaecology Research 2023-02-24

Langerhans cell histiocytosis is a great imitator of other diseases with an often-delayed diagnosis leading to concerning delay in commencing treatment. We present the case male who was previously diagnosed Hailey-Hailey disease, whom several treatment options had failed, referred dermatology team for evaluation 3-month atypical, extensive, painful and pruritic cutaneous flexural eruption. On systems review, he reported 2-year history polyuria polydipsia. Repeat skin biopsy revealed...

10.1136/bcr-2022-254205 article EN BMJ Case Reports 2023-08-01

Abstract Mid‐dermal elastolysis is an acquired skin condition affecting the elastin fibers of dermis, resulting in laxity skin. We report a case mid‐dermal for which novel treatment with mycophenolate mofetil was successful.

10.1111/pde.13511 article EN Pediatric Dermatology 2018-04-23

Abstract Low‐flow vascular malformations are rare congenital anomalies due to errors in development and may be associated with known pathogenic genetic variants. Slow flow through the blood vessels can lead localized intralesional thromboses, which cause debilitating pain impair quality of life. We present a case venous malformation variant TEK gene 38‐year‐old woman whom treatment low dose rivaroxaban was successful controlling symptoms chronic intravascular coagulation.

10.1111/ajd.13856 article EN Australasian Journal of Dermatology 2022-04-23
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