A5066543621- Ionosphere and magnetosphere dynamics
- Geophysics and Gravity Measurements
- Astrophysics and Cosmic Phenomena
- Plant Pathogens and Fungal Diseases
- Mycorrhizal Fungi and Plant Interactions
- Microbial Community Ecology and Physiology
- Earthquake Detection and Analysis
- Seismic Waves and Analysis
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Fungal Biology and Applications
- Metabolomics and Mass Spectrometry Studies
- Urticaria and Related Conditions
- Plant Disease Resistance and Genetics
- Tumors and Oncological Cases
- Microbial Natural Products and Biosynthesis
- Histiocytic Disorders and Treatments
- Higher Education Research Studies
- Geochemistry and Geologic Mapping
- Inflammasome and immune disorders
- Vascular Malformations and Hemangiomas
- Oral microbiology and periodontitis research
- Career Development and Diversity
- Plant Pathogens and Resistance
- Bacteriophages and microbial interactions
Los Alamos National Laboratory
2020-2025
University of Memphis
2024
National Society of Black Engineers
2024
University of Colorado Denver
2024
Michigan State University
2023-2024
Government of the United States of America
2024
Indiana University – Purdue University Indianapolis
2024
University of New Mexico
2017-2020
The Royal Melbourne Hospital
2014-2019
Peter MacCallum Cancer Centre
2019
Optimal use of whole-exome sequencing (WES) in the pediatric setting requires an understanding who should be considered for testing and when it performed to maximize clinical utility cost-effectiveness.
Interactions among host, microbiota and viral pathogens are complex poorly understood. The goal of the present study is to assess changes in skin microbial community Atlantic salmon (Salmo salar L.) response experimental infection with salmonid alphavirus (SAV). was determined using 16S rDNA pyrosequencing five different groups: control, 7 days after low-dose SAV, 14 high-dose SAV. Both treatment time were strong predictors composition. Skin samples from SAV3 infected fish showed an...
Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some early intervention. The Australasian Vascular Anomalies Network and the Paediatric Dermatology have developed consensus statement for with oral propranolol. Infants that are life threatening, at risk ulceration, or causing significant functional impairment, psychological impact physical deformity should be treated Oral propranolol is safe effective in healthy infants can...
Abstract Knowledge of associations between fungal hosts and their bacterial associates has steadily grown in recent years as the number diversity examinations have increased, but current knowledge is predominantly limited to a small taxa partners. Here, we screened for potential over 700 phylogenetically diverse isolates, representing 366 genera, or tenfold increase compared with previously examined including isolates from several unexplored phyla. Both 16 S rDNA-based exploration four...
Abstract Thermophily is a trait scattered across the fungal tree of life, with its highest prevalence within three families (Chaetomiaceae, Thermoascaceae, and Trichocomaceae), as well some members phylum Mucoromycota. We examined 37 thermophilic thermotolerant species 42 mesophilic for this study identified thermophily ancestral state all prominent fungi. Thermophilic genomes were found to encode various thermostable enzymes, including carbohydrate-active enzymes such endoxylanases, which...
Bacterial-fungal interactions (BFIs) play an integral role in shaping microbial community composition, biogeochemical functions, spatial dynamics, and dispersal. Mycelial networks created by filamentous fungi or other microorganisms (e.g., Oomycetes) act as 'fungal highways' that can be utilized bacteria for transport throughout heterogeneous environments, greatly facilitating their mobility granting them access to regions may challenging impossible reach on own due air pockets within the...
Microbiome research is becoming a mature field with wealth of data amassed from diverse ecosystems, yet the ability to fully leverage multi-omics for reuse remains challenging. To provide view into researchers' behavior and attitudes towards reuse, we surveyed over 700 microbiome researchers evaluate sharing challenges. We found that many are impeded by difficulties metadata records, challenges processing bioinformatics, problems repository submissions. also explored cost constraints at each...
Abstract Benzalkonium chloride is a quaternary ammonium cationic detergent present in number of household products, which can act as major skin irritant. We the case six children who developed granular parakeratosis after exposure to benzalkonium laundry rinse aids, presenting brightly erythematous, tender but minimally pruritic, intertriginous eruption followed by superficial desquamation. The eruptions resolved over 3–4 weeks cessation exposure.
Bacteria-fungi interactions (BFIs) are essential in ecosystem functioning. These modulated not only by local nutritional conditions but also the physicochemical constraints and 3D structure of environmental niche. In soils, unsaturated complex nature substrate restricts dispersal activity bacteria. Under conditions, some bacteria engage with filamentous fungi an interaction (fungal highways) which they use fungal hyphae to disperse. Based on a previous experimental device enrich pairs...
Microbial communities are diverse biological systems that include taxa from across multiple kingdoms of life. Notably, interactions between bacteria and fungi play a significant role in determining community structure. However, these statistical associations more difficult to infer than intra-kingdom due the nature data involved using standard network inference techniques. We quantify challenges cross-kingdom both theoretical practical points view synthetic real-world microbiome data. detail...
Abstract Background The recommended method for histopathological diagnosis of cutaneous melanoma is excisional biopsy, although partial biopsies (shave and punch) are often used. Following a treatment guidelines recommend narrow biopsy to plan definitive management. There limited evidence on the benefits direct wide local excision ( WLE ) following diagnostic biopsies. Methods Retrospective cohort study cases, from two tertiary referral centres January 2013 December 2015. Demographic data,...
Several bacteria have long been known to interact intimately with fungi, but molecular approaches only recently uncovered how cosmopolitan these interactions are in nature. Currently, bacterial-fungal (BFI) inferred based on patterns of co-occurrence amplicon sequencing investigations. However, determining the nature interactions, whether internally or externally associated, remains a grand challenge BFI research. Fluorescence situ hybridization (FISH) is robust method that targets unique...
Radiological investigations have become accepted as an important part of the range facilities required to support severely ill newborn babies. Increasing numbers these very small premature babies now survive although they may undergo a considerable number diagnostic X-ray examinations within first few weeks life. Since infants are so small, many virtually "whole-body" irradiations and it was thought that total doses received might be appreciable. A group such admitted Neonatal Intensive Care...
Pemphigus is an autoimmune B-cell mediated blistering disease associated with significant morbidity and mortality. Rituximab has proven effective for the treatment of steroid-refractory pemphigus, although there controversy over optimum dosing protocol. Additionally, control often requires long-term immunosuppression, even in disease-free periods. We present a case series single-centre follow up nine patients treated two 500-mg doses rituximab separated by 14 days along concurrent adjuvant...
The genus Monosporascus represents an enigmatic group of fungi important in agriculture and widely distributed natural arid ecosystems. Of the nine described species, two (M. cannonballus M. eutypoides) are pathogens on roots members Cucurbitaceae agricultural settings. remaining seven species capable colonizing from a diverse host range without causing obvious disease symptoms. Recent molecular culture studies have shown that nearly ubiquitous as root endophytes environments Southwestern...
The field of microbial forensics has recently sought to develop methods discern biological signatures indicate production for agents. Viral agents have received less attention date. Their obligate propagation in living cells makes purification from cellular material a challenge. This leads potential carryover protein-rich their system. Here we explored proteomic analysis vaccinia virus as model poxvirus system which compare samples propagated different cell lines and subjected schemes. data...
Public sequencing databases are invaluable resources to biological researchers, but assessing data veracity as well the curation and maintenance of such large collections can be challenging. Genomes eukaryotic organelles, chloroplasts other plastids, particularly susceptible assembly errors misrepresentations in these due their close evolutionary relationships with bacteria, which may co-occur within same environment, case when plants. Here, based on sequence similarities bacterial genomes,...