A5100765026- Fluorine in Organic Chemistry
- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Inorganic Fluorides and Related Compounds
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- Metal complexes synthesis and properties
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Spectroscopy and Chemometric Analyses
- Crystal structures of chemical compounds
- Synthesis and Reactions of Organic Compounds
- Oxidative Organic Chemistry Reactions
- Synthetic Organic Chemistry Methods
- Synthesis and Biological Evaluation
- Fungal Plant Pathogen Control
- Asymmetric Hydrogenation and Catalysis
- Smart Agriculture and AI
- Radical Photochemical Reactions
- Remote Sensing and Land Use
- Click Chemistry and Applications
- Advanced biosensing and bioanalysis techniques
Shanghai Institute of Organic Chemistry
2021-2024
University of Chinese Academy of Sciences
2021-2024
National Engineering Research Center for Information Technology in Agriculture
2016-2024
Beijing Academy of Agricultural and Forestry Sciences
2013-2024
Bengbu Medical College
2016-2024
Gansu Agricultural University
2023-2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Chinese Academy of Sciences
2022-2023
Hebei University
2023
An electrochemical asymmetric coupling of secondary acyclic amines with ketones via a Shono-type oxidation has been described, affording the corresponding amino acid derivatives good to excellent diastereoselectivity and enantioselectivity. The addition an N-oxyl radical as redox mediator could selectively oxidize substrate rather than product, although their potential difference is subtle (about 13 mV). This transformation proceeds in absence stoichiometric additives, including metals,...
Open AccessCCS ChemistryRESEARCH ARTICLES2 Apr 2024Cobalt-Catalyzed Electrochemical Enantioselective Reductive Cross-Coupling of Organohalides Shi-Shuo Xu†, Hui Qiu†, Pei-Pei Xie†, Zhen-Hua Wang†, Xiu Wang, Chao Zheng, Shu-Li You and Tian-Sheng Mei Xu† Key Laboratory Organometallic Chemistry, Shanghai Institute Organic University Chinese Academy Sciences, 200032 , Qiu† Xie† Wang† Wang Zheng *Corresponding authors: E-mail Address: [email protected]...
The first Ni(cod)2/PPh3 catalyst system has been established for decarbonylative borylation of aroyl fluorides with bis(pinacolato)diboron. A wide range functional groups in the substrates were well tolerated. ease access starting indicates that these results might become an alternative to existing decarbonylation events.
3,3-Difluoro-1,2-diphenylcyclopropene (CpFluor), a bench-stable fluorination reagent, has been developed in the deoxyfluorination of carboxylic acids to afford various acyl fluorides. This all-carbon-based reagent enabled efficient transformation (hetero)aryl, alkyl, alkenyl, and alkynyl corresponding fluorides under neutral conditions. method was featured by synthesis with in-situ formed CpFluor, as well one-pot amidation reaction via
The selective difluoromethylene insertion into a C–Cu bond is challenging task and currently limited to either single CF2 CuCF3 or double insertions CuC6F5 (or (Z)-CF3CF = CFCu). Achieving both the same even more difficult. Herein, highly controllable CuCF2H species with TMSCF2Br reagent have been described, affording two previously unknown fluoroalkylcopper "Cu(CF2)nCF2H" (n 1 2) independently under different reaction conditions. This work represents first example of in manner. synthetic...
Ni/Cu-cocatalyzed decarbonylative silylation of acyl fluorides with silylboranes has been developed to afford various arylsilanes high efficiency and good functional-group compatibility via carbon-fluorine bond cleavage carbon-silicon formation. Such transformation can not only extend the functionalization type but complement synthetic route for arylsilanes.
Highly substituted alkenes are important synthetic intermediates for pharmaceuticals, and the development of such compounds provides a variety potential alkene monomers functional polyolefin molecules. At present, series...
Ni-catalyzed decarbonylative cyanation of acyl chlorides with trimethylsilyl cyanide has been achieved. This transformation is applicable to the synthesis an array nitrile compounds bearing a wide range functional groups under neutral conditions. The step-by-step experimental studies revealed that reaction sequences present catalytic are oxidative addition, transmetalation, decarbonylation, and reductive elimination.
Nickel-catalyzed decarbonylative stannylation of acyl fluorides under ligand-free conditions was disclosed. A variety aromatic are capable reacting with silylstannanes in the presence cesium fluoride. one-pot stannylation/Migita-Kosugi-Stille reaction benzoyl fluoride, giving rise to direct formation corresponding cross-coupled products, further demonstrated synthetic utility present method. This newly developed methodology a good functional-group compatibility via C-F bond cleavage and C-Sn...
A series of novel nopol derivatives bearing the 1,3,4-thiadiazole-thiourea moiety were designed and synthesized by multi-step reactions in search potent natural product-based antifungal agents. Their structures confirmed FT-IR, NMR, ESI-MS, elemental analysis. Antifungal activity target compounds was preliminarily evaluated vitro methods against Fusarium oxysporum f. sp. cucumerinum, Cercospora arachidicola, Physalospora piricola, Alternaria solani, Gibberella zeae, Rhizoeotnia Bipolaris...
A new difluoroalkylation reagent Sulfox-CF2SO2Ph bearing both sulfoximine and sulfone moieties was prepared from commercially available SulfoxFluor PhSO2CF2H. On one hand, the could act as a (phenylsulfonyl)difluoromethyl radical source under photoredox catalysis, in which arylsulfoximidoyl group is selectively removed. other basic conditions, serve difluorocarbene precursor for S- O-difluoromethylations with O-nucleophiles, respectively, phenylsulfonyl removed (followed by α-elimination of group).
To evaluate effectiveness and safety of titrated oral misoprostol solution (OMS) in comparison with vaginal dinoprostone for cervix ripening labor induction term pregnant women. A multicenter randomized controlled trial women singleton pregnancy indications induction; 481 participants were allocated to receive OMS different doses by hourly administration according the procedure or insert compare maternal outcomes including indication induction, mode outcome delivery, morbidity, neonatal...