Yong Chen

ORCID: 0000-0001-6183-2693
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About
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Research Areas
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • MRI in cancer diagnosis
  • Advanced Neuroimaging Techniques and Applications
  • Fetal and Pediatric Neurological Disorders
  • Atomic and Subatomic Physics Research
  • Cardiac Imaging and Diagnostics
  • Genetic and Kidney Cyst Diseases
  • Advanced X-ray and CT Imaging
  • NMR spectroscopy and applications
  • Brain Tumor Detection and Classification
  • Advanced NMR Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Electron Spin Resonance Studies
  • Renal cell carcinoma treatment
  • Cardiomyopathy and Myosin Studies
  • Nuclear Physics and Applications
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Photoacoustic and Ultrasonic Imaging
  • Advanced Radiotherapy Techniques
  • Colorectal Cancer Screening and Detection
  • Neural dynamics and brain function
  • Ultrasound and Hyperthermia Applications
  • Cardiovascular Effects of Exercise

Yangtze University
2024

Fujian Polytechnic of Information Technology
2024

Case Western Reserve University
2011-2024

University Hospitals of Cleveland
2015-2024

Jinan University
2024

Southern University of Science and Technology
2024

ShenZhen People’s Hospital
2024

Ningxia Medical University
2024

Huazhong University of Science and Technology
2010-2024

Ningxia Medical University General Hospital
2024

Purpose To introduce a two-dimensional MR fingerprinting (MRF) technique for quantification of T1, T2, and M0 in myocardium. Methods An electrocardiograph-triggered MRF method is introduced mapping myocardial during single breath-hold as short four heartbeats. The pulse sequence uses variable flip angles, repetition times, inversion recovery T2 preparation dephasing times. A dictionary possible signal evolutions simulated each scan that incorporates the subject's unique variations heart...

10.1002/mrm.26216 article EN Magnetic Resonance in Medicine 2016-04-01

Purpose The goal of this study is to characterize and improve the accuracy 2D magnetic resonance fingerprinting (MRF) scans in presence slice profile (SP) B 1 imperfections, which are two main factors that affect quantitative results MRF. Methods SP imperfections characterized corrected separately. effect by simulating radiofrequency pulse dictionary, acquiring a map using Bloch‐Siegert method before each scan. accuracy, precision, repeatability proposed evaluated phantom studies. effects...

10.1002/mrm.26580 article EN Magnetic Resonance in Medicine 2017-01-11

The purpose of this study was to accelerate the acquisition and reconstruction time 3D magnetic resonance fingerprinting scans.

10.1002/mrm.26886 article EN Magnetic Resonance in Medicine 2017-08-22

T1-weighted image (T1WI) and T2-weighted (T2WI) are the two routinely acquired magnetic resonance (MR) modalities that can provide complementary information for clinical research usages. However, relatively long acquisition time makes vulnerable to motion artifacts. To speed up imaging process, various algorithms have been proposed reconstruct high-quality images from under-sampled k-space data. most of existing only rely on mono-modality reconstruction. In this paper, we propose combine MR...

10.1109/tbme.2018.2883958 article EN IEEE Transactions on Biomedical Engineering 2018-11-29

Magnetic resonance fingerprinting (MRF) is a quantitative imaging technique that can simultaneously measure multiple important tissue properties of human body. Although MRF has demonstrated improved scan efficiency as compared to conventional techniques, further acceleration still desired for translation into routine clinical practice. The purpose this paper accelerate acquisition by developing new quantification method allows accurate with fewer sampling data. Most the existing approaches...

10.1109/tmi.2019.2899328 article EN IEEE Transactions on Medical Imaging 2019-02-13

Purpose To reduce the acquisition time needed to obtain reliable parametric maps with Magnetic Resonance Fingerprinting. Methods An iterative‐denoising algorithm is initialized by reconstructing MRF image series at low resolution. For subsequent iterations, method enforces pixel‐wise fidelity best‐matching dictionary template then acquired data slightly higher spatial After convergence, desirable resolution are obtained through matching of final series. The proposed was evaluated on phantom...

10.1002/mrm.25776 article EN Magnetic Resonance in Medicine 2015-06-30

Purpose To develop a fast three-dimensional method for simultaneous T1 and T2 quantification breast imaging by using MR fingerprinting. Materials Methods In this prospective study, variable flip angles magnetization preparation modules were applied to acquire fingerprinting data each partition of set. A postprocessing was implemented singular value decomposition. The proposed technique first validated in phantoms then 15 healthy female participants (mean age, 24.2 years ± 5.1 [standard...

10.1148/radiol.2018180836 article EN Radiology 2018-10-30

MR Fingerprinting (MRF) is a relatively new imaging framework capable of providing accurate and simultaneous quantification multiple tissue properties for improved characterization disease diagnosis. While 2D MRF has been widely available, extending the method to 3D an actively pursued area research as approach can provide higher spatial resolution better with inherently signal-to-noise ratio. However, high requires lengthy acquisition times, especially large volume, making it impractical...

10.1016/j.neuroimage.2019.116329 article EN cc-by NeuroImage 2019-11-03

High‐field preclinical MRI scanners are now commonly used to quantitatively assess disease status and the efficacy of novel therapies in a wide variety rodent models. Unfortunately, conventional methods highly susceptible respiratory cardiac motion artifacts resulting potentially inaccurate misleading data. We have developed an initial 7.0‐T implementation MR fingerprinting (MRF) methodology which has been described previously for clinical imaging applications. The MRF technology combines...

10.1002/nbm.3262 article EN NMR in Biomedicine 2015-02-02

This study introduces a technique for simultaneous multislice (SMS) cardiac magnetic resonance fingerprinting (cMRF), which improves the slice coverage when quantifying myocardial T 1, 2 , and M 0 . The single‐slice cMRF pulse sequence was modified to use multiband (MB) RF pulses SMS imaging. Different phase schedules were used excite each slice, similar POMP or CAIPIRINHA, imparts tissues with distinguishable slice‐specific magnetization evolution over time. Because of high net acceleration...

10.1002/nbm.4041 article EN NMR in Biomedicine 2018-12-18

To develop a rapid 2D MR fingerprinting technique with submillimeter in-plane resolution using deep learning-based tissue quantification approach.A and high-resolution was developed for brain T1 T2 quantification. The acquisition performed FISP-based sequence spiral trajectory 0.8-mm resolution. A method used to replace the standard template matching improved characterization. novel network architecture (i.e., residual channel attention U-Net) proposed improve details in estimated maps....

10.1002/mrm.28136 article EN Magnetic Resonance in Medicine 2019-12-19

Background The 3D breast magnetic resonance fingerprinting (MRF) technique enables T 1 and 2 mapping in tissues. Combined repeatability reproducibility studies on relaxometry are lacking. Purpose To assess test–retest two‐visit interscanner of the MRF a single‐institution setting. Study Type Prospective. Subjects Eighteen women (median age 29 years, range, 22–33 years) underwent Visit scans scanner 1. Ten these scan repositioning after 10‐minute interval. Thirteen had within 7–15 days same...

10.1002/jmri.26717 article EN Journal of Magnetic Resonance Imaging 2019-03-20

Although both relaxation and diffusion imaging are sensitive to tissue microstructure, studies have reported limited sensitivity robustness of using or conventional alone characterize microstructure. Recently, it has been shown that tensor-valued encoding joint relaxation-diffusion quantification enable more reliable compartment-specific microstructural properties. However, scan times acquire such data can be prohibitive. Here, we aim simultaneously quantify MR fingerprinting (MRF) b-tensor...

10.1002/mrm.29352 article EN cc-by Magnetic Resonance in Medicine 2022-06-17

BackgroundTo achieve imaging report standardization and improve the quality efficiency of intra-interdisciplinary clinical workflow, we proposed an intelligent layout system (IILS) for a decision support system-based ubiquitous healthcare service, which is lung nodule management using medical images.MethodsWe created IILS based on deep learning workflow optimization identification nodules. Our utilized plus adaptive auto tool, trained tested neural network with data from all main CT...

10.1016/j.ebiom.2019.05.040 article EN cc-by-nc-nd EBioMedicine 2019-05-23

Bone age assessment (BAA) from hand radiographs is crucial for diagnosing endocrinology disorders in adolescents and supplying therapeutic investigation. In practice, due to the conventional clinical being a subjective estimation, accuracy of BAA relies highly on pediatrician's professionalism experience. Recently, many deep learning methods have been proposed automatic estimation bone had good results. However, these do not exploit sufficient discriminative information or require additional...

10.3389/frai.2023.1142895 article EN cc-by Frontiers in Artificial Intelligence 2023-03-02

Quantitative MRI techniques such as MR fingerprinting (MRF) promise more objective and comparable measurements of tissue properties at the point-of-care than weighted imaging. However, few direct cross-modal comparisons MRF's repeatability reproducibility versus acquisitions have been performed. This work proposes a novel fully automated pipeline for quantitatively comparing imaging performance in vivo via atlas-based sampling.

10.1002/mrm.29983 article EN cc-by-nc-nd Magnetic Resonance in Medicine 2024-01-09

Purpose To develop an ultrafast T 1 mapping method for high‐resolution, volumetric measurements in the abdomen. Methods The Look‐Locker was combined with a stack‐of‐spirals acquisition accelerated using three‐dimensional (3D) through‐time spiral GRAPPA reconstruction fast data acquisition. A segmented k‐space scheme proposed and time delay between segments recovery of longitudinal magnetization optimized Bloch equation simulations. accuracy this validated phantom experiment vivo were...

10.1002/mrm.25693 article EN Magnetic Resonance in Medicine 2015-05-18

Objectives The goal of this study was to develop free-breathing high–spatiotemporal resolution dynamic contrast-enhanced liver magnetic resonance imaging using non-Cartesian parallel acceleration, and quantitative perfusion mapping. Materials Methods This approved by the local institutional review board written informed consent obtained from all participants. Ten healthy subjects 5 patients were scanned on a Siemens 3-T Skyra scanner. A stack-of-spirals trajectory undersampled in-plane with...

10.1097/rli.0000000000000135 article EN Investigative Radiology 2015-01-22

Quantitative T1 and T2 mapping in the abdomen provides valuable information tissue characterization but is technically challenging due to respiratory motions. The proposed technique integrates magnetic resonance fingerprinting (MRF) pilot tone (PT) navigator with retrospective gating provide simultaneous quantification of multiple properties a single acquisition without breath-holding or patient set-up.To develop free-breathing abdominal MRF for quantitative abdomen.Prospective.Twelve...

10.1002/jmri.27673 article EN Journal of Magnetic Resonance Imaging 2021-05-05

Background MR fingerprinting (MRF) provides rapid and simultaneous quantification of multiple tissue parameters in a single scan. Purpose To evaluate kidney MRF technique at 3.0 T phantoms, healthy volunteers, patients. Materials Methods A 15-second acquisition was designed with 12 segments, range low flip angles (5°-12°), magnetization preparation schema (T1, T2, fat suppression), an undersampled spiral trajectory. This first validated vitro using standardized T1 T2 phantoms. Kidney maps...

10.1148/radiol.2021202302 article EN Radiology 2021-06-08

The standard clinical acquisition for left ventricular functional parameter analysis with cardiovascular magnetic resonance (CMR) uses a multi-breathhold multi-slice segmented balanced SSFP sequence. Performing multiple long breathholds in quick succession coverage the short-axis orientation can lead to fatigue and is challenging patients severe cardiac or respiratory disorders. This study combines encoding efficiency of six-fold undersampled 3D stack spirals sequence through-time spiral...

10.1186/s12968-014-0065-1 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2014-09-10
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