A5081158440- Microbial Natural Products and Biosynthesis
- Seaweed-derived Bioactive Compounds
- Echinoderm biology and ecology
- Protein Hydrolysis and Bioactive Peptides
- Marine Sponges and Natural Products
- Enzyme Catalysis and Immobilization
- Polyamine Metabolism and Applications
- Plant Pathogens and Fungal Diseases
- Synthesis and Biological Activity
- Amino Acid Enzymes and Metabolism
- Global Trade and Competitiveness
- Microbial Community Ecology and Physiology
- Aquatic life and conservation
- Melanoma and MAPK Pathways
- Mycotoxins in Agriculture and Food
- Food composition and properties
- Cancer Immunotherapy and Biomarkers
- Pancreatic function and diabetes
- Chemical Synthesis and Analysis
- Inflammatory mediators and NSAID effects
- Web Applications and Data Management
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Microbial metabolism and enzyme function
- Selenium in Biological Systems
- Osteoarthritis Treatment and Mechanisms
First Affiliated Hospital of Wannan Medical College
2023
Wannan Medical College
2023
Jiangsu Food and Pharmaceutical Science College
2019-2022
Chinese PLA General Hospital
2014
Biology Institute of Shandong Academy of Sciences
2006-2012
Shandong Academy of Agricultural Sciences
2011-2012
Chinese Academy of Sciences
2012
Chinese Academy of Inspection and Quarantine
2009
AIM:To investigate the antioxidant activity of chitooligosaccharides (COSs) on pancreatic islet cells in diabetic rats induced by streptozotocin. METHODS:The effect COSs was detected under optical microscopy and with colorimetric assay gel electrophoresis.The activities glutathione peroxidase superoxide dismutase, total capacity, content malondialdehyde serum tissue slices pancreas were examined after 60 d to determine streptozotocin-induced diabetes rats. RESULTS:COSs can prohibi t...
Abstract BACKGROUND: Xylitol, a sugar alcohol widely used in food and pharmaceutical industries, can be produced through biological reduction of xylose present hemicellulose hydrolysates by Candida tropicalis . However, the aeration rate by‐products originating from hydrolysis strongly inhibit production xylitol fermentation process. A two‐stage fed‐batch system was developed to reduce these inhibitory effects improve corn cob C. RESULTS: Results batch fermentations indicated that high could...
Abstract Phenyllactic acid (PLA) has gained a lot of attention due to its broad antimicrobial activity, but the mechanism antifungal action been barely reported until now. Herein, inhibitory activity PLA against Aspergillus flavus spore germination and were preliminarily investigated. Results indicated that had strong A. with minimal concentration (MIC) fungicidal (MFC) 6 12 mg/ml, respectively. As observed by scanning electron microscopy (SEM), spores displayed wrinkled shrunken appearance...
Abstract BACKGROUND: Saccharomyces cerevisiae is one of the main microorganisms that can produce S ‐adenosylmethionine (SAM) from L‐methionine and ATP with high productivity. To satisfy requirement for SAM synthesis, sufficient oxygen should be supplied to medium improve aerobic metabolism in S. . In this study, n ‐hexadecane used as vector enhancement production by yeast was investigated. RESULTS: N most favorable cell growth synthesis when added at time inoculation. It could increase...
Abstract Background Cutaneous melanoma (CM) has an overall poor prognosis due to a high rate of metastasis. This study aimed explore the role hypoxia-related genes (HRGs) in CM. Methods We first used on-negative matrix factorization consensus clustering (NMF) cluster CM samples and preliminarily analyzed relationship HRGs immune cell infiltration. Subsequently, we identified prognostic-related hub by univariate COX regression analysis least absolute shrinkage selection operator (LASSO)...
A new compound, 4-acetyl-5-hydroxy-3, 6, 7-trimethylbenzofuran-2(3H)-one (1), together with two known compounds, 2-carboxy-3-(2-hydroxypropanyl) phenol (2) and 5-methyl- 6-hydroxy-8-methyoxy-3-methylisochroman (3) were isolated from the fungus Alternaria sp. (HS-3) associated a sea cucumber Yellow Sea in China. Their structures elucidated by spectral methods.