A5058437975- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Osteoarthritis Treatment and Mechanisms
- AI in cancer detection
- Periodontal Regeneration and Treatments
- Psoriasis: Treatment and Pathogenesis
- Optical Coherence Tomography Applications
- Temporomandibular Joint Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Oropharyngeal Anatomy and Pathologies
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Artificial Intelligence in Healthcare and Education
- Face recognition and analysis
- Explainable Artificial Intelligence (XAI)
- Mesenchymal stem cell research
- Dermatological diseases and infestations
- Molecular Biology Techniques and Applications
- Silk-based biomaterials and applications
- Proteoglycans and glycosaminoglycans research
- Ocular Diseases and Behçet’s Syndrome
- Nail Diseases and Treatments
- Medicine and Dermatology Studies History
- Pharmaceutical studies and practices
University Hospital Augsburg
2023-2025
University of Augsburg
2023-2024
RELX Group (United States)
2023
Augsburg University
2023
Massachusetts General Hospital
2021-2022
Actinic keratosis (AK) is a common skin cancer in situ that can progress to invasive SCC. Line-field confocal optical coherence tomography (LC-OCT) has emerged as non-invasive imaging technique aid diagnosis. Recently, machine-learning algorithms have been developed automatically assess the PRO score of AKs based on dermo-epidermal junction's (DEJ's) protrusion LC-OCT images. A dataset 19.898 images from 80 histologically confirmed AK lesions was used test performance previous validated...
To date, therapeutic responses in plaque psoriasis are evaluated with clinical scores. No objective examination has been established. A recently developed non-invasive imaging tool, line-field confocal optical coherence tomography (LC-OCT), enables the vivo live of skin changes under therapy. The aim this study was to measure response clinically and LC-OCT, comparing subjectively scored epidermal an AI-supported analysis. This prospective, observational included 12 patients starting a...
The histological PRO score (I-III) helps to assess the malignant potential of actinic keratoses (AK) by grading dermal-epidermal junction (DEJ) undulation. Line-field confocal optical coherence tomography (LC-OCT) provides non-invasive real-time quantification. From LC-OCT imaging data, training an artificial intelligence (AI), using Convolutional Neural Networks (CNNs) for automated quantification AK in vivo may be achieved.CNNs were trained segment images healthy skin and AK. models...
The Grand-AID research project, consisting of GRANDEL-The Beautyness Company, the dermatology department Augsburg University Hospital and Chair IT Infrastructure for Translational Medical Research at University, is currently researching development a digital skin consultation tool that uses artificial intelligence (AI) to analyze user's ultimately perform personalized analysis customized care routine. Training AI requires annotation various features on facial images. central question whether...
Abstract Objectives Basal cell carcinoma (BCC) is the most common skin tumor with an annually increasing incidence. Standard care requires several visits for diagnosis and treatment. Optical coherence tomography (OCT) as a diagnostic tool increases sensitivity (95%) specificity (77%) of BCC. Although laser therapy not standard care, long‐pulsed 1064 nm Nd:YAG seems to be promising option. However, data are scarce. The published papers had short follow‐up (FU) time used some extent inferior...
Generalized pustular psoriasis (GPP) is a potentially life-threatening orphan disease. Interleukin (IL)-36 known pathogenetic key driver of GPP. The IL-36 receptor inhibitor spesolimab has shown efficacy and safety in clinical trials. However, evidence for outside trials limited. To provide additional the use beyond trials, we evaluated individual patient data as part Compassionate Use Program (CUP) GPP patients Germany. Adult with an acute flare received 900 mg intravenously at baseline...
Temporomandibular Joint (TMJ) disorders affect up to 10-40% of the population and if left untreated, may eventually lead Osteoarthritis (OA) TMJ. In vivo TMJ repair regeneration has received significant attention represents a promising approach for treatment degenerative disorders. The aim this study was present pre-clinical mouse model articular cartilage defect evaluate utility potential tissue engineered therapy utilizing Mesenchymal Stem Cells (MSCs) derived from mice condyle, hydrogel,...
To date, there is no structured program for dermatoscopy training during residency in Germany. Whether and how much acquired left to the initiative of each resident, although one core competencies dermatological daily practice. The aim study was establish a curriculum at University Hospital Augsburg.An online platform with modules created, accessible regardless time place. Practical skills were under personal guidance expert. Participants tested on their level knowledge before after...
Bislang gibt es in Deutschland kein strukturiertes Programm für die Dermatoskopieausbildung während der Facharztausbildung. Es bleibt Initiative des einzelnen Assistenzarztes überlassen, ob und welchem Umfang er sich Dermatoskopie weiterbildet, obwohl zu den Kernkompetenzen dermatologischen Ausbildung täglichen Praxis gehört. Ziel Studie war Etablierung eines strukturierten Dermatoskopie-Curriculums Facharztausbildung am Universitätsklinikum Augsburg.Es wurde eine Online-Plattform mit...
Zusammenfassung Hintergrund Mit Hilfe des histologischen PRO‐Scores (I–III) kann das Risiko einer malignen Transformation aktinischer Keratosen (AK) abgeschätzt werden, indem er Ausmaß der Undulation und basalen Proliferation dermoepidermalen Junktionszone (DEJ) bewertet. Die konfokale Line‐Field optische Kohärenztomographie (LC‐OCT) ermöglicht eine nichtinvasive Bestimmung in Echtzeit. Anhand von LC‐OCT‐Bilddatensätzen künstliche Intelligenz (KI) mit Convolutional Neural Networks (CNN) zur...