A5027523442- Wound Healing and Treatments
- Diagnosis and Treatment of Venous Diseases
- Pressure Ulcer Prevention and Management
- Autoimmune and Inflammatory Disorders
- Skin Diseases and Diabetes
- Contact Dermatitis and Allergies
- Diabetic Foot Ulcer Assessment and Management
- Autoimmune Bullous Skin Diseases
- Oral Health Pathology and Treatment
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Inflammatory Myopathies and Dermatomyositis
- Dermatology and Skin Diseases
- Dermatologic Treatments and Research
- Hidradenitis Suppurativa and Treatments
- Cutaneous Melanoma Detection and Management
- Dermatological and COVID-19 studies
- Venous Thromboembolism Diagnosis and Management
- Nail Diseases and Treatments
- Surgical Sutures and Adhesives
- Systemic Sclerosis and Related Diseases
- Urticaria and Related Conditions
- Allergic Rhinitis and Sensitization
- Medical Practices and Rehabilitation
- Occupational exposure and asthma
Universitätsklinikum Erlangen
2016-2025
Friedrich-Alexander-Universität Erlangen-Nürnberg
2011-2024
Essen University Hospital
2022
Molina Center for Energy and the Environment
2022
Weatherford College
2021
Medizinische Akademie Erfurt
2017-2020
University Dermatology
2017
University Hospital Ulm
2012
Abstract Introduction Evidence from a number of open-label, uncontrolled studies has suggested that rituximab may benefit patients with autoimmune diseases who are refractory to standard-of-care. The objective this study was evaluate the safety and clinical outcomes in several standard-of-care-refractory (within rheumatology, nephrology, dermatology neurology) other than rheumatoid arthritis or non-Hodgkin's lymphoma real-life setting. Methods Patients received having shown an inadequate...
In recent years it has been controversially discussed in the literature if smoking is associated with activity of cutaneous lupus erythematosus (CLE) and efficacy antimalarial agents.To investigate influence on disease severity treatment patients CLE using Core Set Questionnaire European Society Cutaneous Lupus Erythematosus (EUSCLE).A total 1002 (768 female, 234 male) different subtypes were included this cross-sectional study, which was performed 14 countries. Smoking behaviour assessed by...
Abstract: Depression is a very common comorbidity in patients with chronic wounds. At least 30% of those suffer from depressive symptoms or anxiety. To measure impairment on daily life, different quality life (QoL) questionnaires can be used as well specialized to evaluate levels depression. In this review, we present some the current measurement tools and effects depression QoL. often associated wound duration, odor wounds, furthermore pain immobility. On other hand, might reduce healing...
Calciphylaxis (CP) is a serious, potentially life-threatening disease that presents with medial calcification of small-sized vessels and painful ischemic ulcerations. Although calciphylaxis frequently seen in patients end-stage kidney on dialysis (calcific uremic arteriolopathy, CUA), there are reported cases nonuremic (NUC), which often remain undiagnosed. We conducted retrospective chart review at our dermatological hospital evaluated data concerning the epidemiology, comorbidities,...
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown etiology which can manifest in ulcerative skin lesions and widely recognised association with diabetes mellitus. Our aim was to improve knowledge about the epidemiology clinical course NL evaluate treatment approaches. This multicentre retrospective study covered data from 52 patients lower leg, treated between 2006 2011. Data three German dermatological centres were analysed. Twelve men 40 women, aged 15 87 years,...
Patients with lower leg dermatitis, chronic venous insufficiency or ulcers have a high prevalence of contact sensitization.To identify the current spectrum allergens in these patients.Data Information Network Departments Dermatology on 5264 patients above diagnoses from years 2003 to 2014 (study group) were compared data 4881 corresponding 1994 (historical control and group without (n = 55 510).Allergic dermatitis was diagnosed less frequently study than historical (25.9% versus 16.9%; p <...
Surgical wounds and periwound skin require protection to prevent complications, which affect clinical outcomes patient quality of life. This study surveyed 45 health professionals treating 394 patients elicit their experiences the performance, quality, ease application usability sterile surgical wound dressing Curapor under routine conditions. Most (90%) were acute, including postoperative wounds, lacerations, cuts abrasions. The average wear time per was 2.08 days; 94% experienced no...
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology which can manifest in ulcerative skin lesions and widely recognised association with diabetes. We evaluated total 100 patients to improve knowledge about the epidemiology clinical course NL. Additionally we focused on treatment options according evidence level expert opinion. To examine features necrobiosis give recommendations for topical systemic treatment. This multicentre retrospective study covers data from...
Successful management of patients with leg ulcers requires identification the underlying etiology, subsequent initiation causal treatment, if feasible. Supplementary measures first choice include stage-adjusted wound usually combined compression therapy. The significance systemic drugs has been subject controversial debate, depending on cause condition. present review article is therefore meant to highlight current aspects drug therapies for treatment associated chronic venous insufficiency,...
A significant number of chronic venous ulcers (CVUs) fail to heal despite guideline-conform standard care. Skin-derived ABCB5+ mesenchymal stem cells (MSCs) can dampen the sustained IL-1β-driven inflammation present in wounds. Based on their wound healing-facilitating effects a mouse CVU model and an autologous first-in-human study, MSCs have emerged as potential candidate for cell-based advanced therapy non-healing CVUs. In interventional, multicenter, single-arm, phase I/IIa clinical...
<b><i>Background:</i></b> Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology. Randomized controlled studies are not available due to it being an orphan disease. <b><i>Objectives:</i></b> We evaluated patients in 2 dermatological centres cluster data about epidemiology, the therapeutic approaches for NL, and their efficacy. <b><i>Materials Methods:</i></b> Comorbidity efficacy applied...
Zusammenfassung Die Abklärung chronischer Wunden ist essenziell für die Einleitung einer kausaltherapeutischen Behandlung. Zur diagnostischen Einordnung der Wundgenese kann es erforderlich sein, eine Biopsie zur histologischen und/oder mikrobiologischen Aufarbeitung zu entnehmen. Besteht klinisch Verdacht auf spezifische Ursache Wunde wie Neoplasie, entzündliche Dermatose oder erregerbedingte Wunde, so unverzüglich weiteren Diagnostik erforderlich. Zeigt sich unter adäquat erscheinenden...
The possible impact of nutritional status on healing and course disease in patients with chronic wounds is widely suggested, however, most data are based small groups no control group minor afflictions. Clear diagnostic strategies missing. To analyse detail the wound relative to healthy controls a large patient population. We screened 50 for their body mass index (BMI), Mini-Nutritional Assessment (MNA), Nutritional Risk Screening (NRS), as well additional laboratory investigations....
Summary This S2k guideline on venous leg ulcers was created the initiative and under leadership of German Society Phlebology Lymphology (DGPL). The group also consisted representatives from for Lymphology, Dermatological Society, General Medicine, Angiology, Vascular Surgery Surgery, Dermatosurgery, Wound Healing Treatment, Professional Association Phlebologists Lymphologists Initiative Chronische Wunden. aim this is to combine different approaches levels knowledge respective professional...
Introduction: Automation bias poses a significant challenge to the effectiveness of Clinical Decision Support Systems (CDSS), potentially compromising diagnostic accuracy. Previous research highlights trust, self-confidence, and task difficulty as key determinants. With increasing availability AI-enabled CDSS, automation attains new attention. This study therefore aims identify factors influencing in task. Methods: A quantitative intervention with participants from different backgrounds (n =...
Abstract Pyoderma gangrenosum (PG) is a non‐infectious, neutrophilic dermatosis that was difficult to diagnose in clinical practice. Today, the PARACELSUS score validated tool for diagnostics. Based on this score, patients with clearly diagnosed PG were examined regard predilection sites. In retrospective study, data of from University Hospitals Essen and Erlangen analysed whom diagnosis could be confirmed using score. A total 170 patients, 49 men (29%) 121 women (71%) an average age at...
Livedoid vasculopathy and calciphylaxis are rare skin disorders. Large cohorts of patients have been missing so far for detailed analysis.Data from diagnosis-related groups (DRGs) hospitalized cases livedoid (ntotal = 1357) 699) were analysed the years 2008-2013 concerning sex, age frequency diagnosis. To avoid deviations to non-relevant secondary diagnosis due changes in ICD-10 indices, we selected two most recent available 2013 2014 evaluation accompanying diagnoses both, (n 519) 324)....