A5001326353- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- T-cell and B-cell Immunology
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Systemic Sclerosis and Related Diseases
- Eosinophilic Disorders and Syndromes
- Skin Protection and Aging
- Atherosclerosis and Cardiovascular Diseases
- Bioactive Natural Diterpenoids Research
- Dermatology and Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Reproductive System and Pregnancy
- Inflammatory Myopathies and Dermatomyositis
- Immune Cell Function and Interaction
- melanin and skin pigmentation
- Chronic Lymphocytic Leukemia Research
- Plant-based Medicinal Research
- Contact Dermatitis and Allergies
- Multiple Sclerosis Research Studies
- Psychedelics and Drug Studies
- Bee Products Chemical Analysis
- Cytokine Signaling Pathways and Interactions
- Toxin Mechanisms and Immunotoxins
- Forensic Toxicology and Drug Analysis
Heidelberg University
2012-2023
German Cancer Research Center
2012-2023
University Hospital Heidelberg
2020-2021
DKFZ-ZMBH Alliance
2013-2017
University of Münster
2012
Cutaneous lupus erythematosus (CLE) is a rare inflammatory autoimmune disease with heterogeneous clinical manifestations. To date, no therapeutic agents have been licensed specifically for patients this entity, and topical systemic drugs are mostly used 'off-label'. The aim of the present guideline was to achieve broad consensus on treatment strategies CLE by European subcommittee, guided Dermatology Forum (EDF) supported Academy Venereology (EADV). In total, 16 participants were included in...
In recent years it has been controversially discussed in the literature if smoking is associated with activity of cutaneous lupus erythematosus (CLE) and efficacy antimalarial agents.To investigate influence on disease severity treatment patients CLE using Core Set Questionnaire European Society Cutaneous Lupus Erythematosus (EUSCLE).A total 1002 (768 female, 234 male) different subtypes were included this cross-sectional study, which was performed 14 countries. Smoking behaviour assessed by...
Objective The aim of the study was to assess efficacy and safety fumaric acid esters (FAEs) in patients with cutaneous lupus erythematosus (CLE). Methods In this 24-week, prospective, open-label, phase II pilot study, 11 CLE, refractory topical corticosteroids, were included. primary endpoint evaluation FAEs after 24 weeks treatment as assessed by Revised Cutaneous Lupus Disease Area Severity Index (RCLASI). Results Compared baseline, significant improvement mean total RCLASI activity score...
5-(2-Aminopropyl)benzofuran (5-APB) and 6-(2-aminopropyl)benzofuran (6-APB) are benzofuran analogues of amphetamine belong to the category new psychoactive substances. Despite already published fatal 5- 6-APB intoxication after consumption both substances in most cases, no sensitive method for simultaneous detection quantification these compounds human blood samples has yet been developed. Therefore, an easy fast sample preparation specific high-performance liquid chromatography tandem mass...