A5101974470- Pancreatic and Hepatic Oncology Research
- Cell Adhesion Molecules Research
- Cancer Cells and Metastasis
- Cancer, Hypoxia, and Metabolism
- Glycosylation and Glycoproteins Research
- Cancer-related Molecular Pathways
- Ferroptosis and cancer prognosis
- Virus-based gene therapy research
- Polysaccharides and Plant Cell Walls
- Cancer Mechanisms and Therapy
- Carbohydrate Chemistry and Synthesis
- Sesquiterpenes and Asteraceae Studies
- Animal Virus Infections Studies
- Advanced Proteomics Techniques and Applications
- RNA modifications and cancer
- Inflammatory mediators and NSAID effects
- Natural product bioactivities and synthesis
- Cancer Research and Treatments
- Caveolin-1 and cellular processes
- Herpesvirus Infections and Treatments
China Medical University
2016-2022
South China Agricultural University
2022
Jinzhou Medical University
2019-2021
Pancreatic cancer is the fourth leading cause of death, with a 5-year survival rate only 1–4%. Integrin-mediated cell adhesion critical for initiation, progression, and metastasis cancer. In this study we investigated role integrin b4 (ITGB4) its phosphorylation at tyrosine Y1510 (p-ITGB4-Y1510) in tumorigenesis pancreatic We analyzed expression ITGB4 p-ITGB4-Y1510 tissue lines using immunohistochemistry, Western blot, or semi-quantitative reverse transcription PCR. were highly expressed (n...
Mechanisms of abnormal protein phosphorylation that regulate cell invasion and metastasis in pancreatic cancer remain obscure. In this study, we used high-throughput array to test two lines (PC-1 cells with a low, PC-1.0 high potential for metastasis). We noted total 57 proteins revealed differential expression (fold change ≥ 2.0). Six candidate were further validated by western blot results found be accordance the array. Of proteins, 32 up-regulated (e.g. CaMK1-α P90RSK) mainly involved...
Since the chicken infectious anemia virus (CIAV) was discovered in 1979, which has been reported as an economically significant and immunosuppressive poultry disease world. A novel clinical detection method for prevention control of CIAV sector is urgently needed. Here, we established a real-time recombinase-aided amplification assay (RAA) on-site with rapid, highly sensitive, strongly specific, low-cost, simple operational molecular diagnosis method. The primers probe were developed using...