Background: The Montreal Cognitive Assessment (MoCA) has a high sensitivity for detecting cognitive dysfunction. Swedish normative data does not exist and international norms are often derived from populations where impairment been screened thoroughly assessed to exclude subjects with dementia or mild impairment. Objective: To establish MoCA develop regression-based norm calculator based on large, well-examined cohort. Methods: was administered 860 randomly selected elderly people...

There is a growing concern among health authorities that an increasing number of people in the Western world become overweight and even obese. It well known obesity related to several diseases (e.g., diabetes, stroke, high blood pressure) such lead early death. has also been discussed whether themselves or relation cognitive decline. On basis data from large, population‐based, prospective study we examined three domains: episodic memory, semantic spatial ability. Two body measures were used...

Abstract The time course of the active state, force‐velocity relation and series compliance were investigated in isolated papillary muscles rabbit.—The curve defined at a precise length state contractile element given after stimulus could be fitted by Hill's equation. shape remained constant during activity period, indicating that ability to produce motion tension undergo parallel changes myocardial contraction cycle.—The unit, had slow onset (1/3–1/2 entire period being needed for...

Abstract Aims We aimed to search for associations between cognitive test results with mortality and rehospitalization in a Swedish prospective heart failure (HF) patient cohort. Methods Two hundred eighty‐one patients hospitalized HF (mean age, 74 years; 32% women) were assessed using tests: Montreal Cognitive Assessment (MoCA), A Quick Test of speed, Trail Making A, Symbol Digit Modalities Test. The mean follow‐up time censored at or death was 13 months (interquartile range, 14) 28 29),...

The influence of the sympathetic nervous system on secretion thyroid hormone was studied in mice, which TSH had been blocked by exogenous thyroxine. Stimulation right cervical trunk for 5–60 sec induced a formation intracellular colloid droplets and an increase blood 131I. droplet restricted to regions supplied this nerve, as judged from distribution catecholamine-containing nerve terminals thyroids animals with left-side sympathectomy. Iv L-norepinephrine (NE) symmetrical Phentolamine...

Abstract The instantaneous relationship between isotonic load and velocity of shortening was studied in rabbit papillary muscles using a quick‐release technique which involved critical damping the lever. force‐velocity curve determined from experimental data by means least squares method computer program. exhibited true hyperbolic shape virtually same values constants b Hill's equation were obtained when analysis carried out during rising or falling phase an isometric contraction. basis...

Sebeya catchment in north-western Rwanda has been subject to frequent floods over the years. Despite recent investments structural measures for flood protection catchment, a event May 2023 caused loss of 97 human lives and damages around 2,200 buildings. The urged authorities invest additional improve management practices minimize cost future events. To support decision-making planning practices, this study conducts hazard assessment using HEC RAS 1D model based on storm events 10 100-year...

Abstract The key objective for recombinant protein production in bacteria is the maximum exploitation of cell factory's potential, whereby often strong expression vectors are used to increase product yield. If metabolic load caused by exceeds host's capacity, system exhausts itself, resulting a loss Excessive plasmid replication observed after inducing gene expression, which greatly contributes overload host cell. transcriptional and translational machineries extremely overstrained. By...

The role of blood pressure (BP) changes in dementia is debatable. We aimed to analyse how resting and postural BP relate incident over a long-term follow-up. In the prospective population-based Malmö Preventive Project, 18,240 study participants (mean age: 45 ± 7 years, 63% male) were examined between 1974 1992 with standing measurement, re-examined 2002 2006 at mean age 68 6 years BP. A total 428 (2.3%) diagnosed through Dec 31, 2009. association risk was studied using...

Abstract Background Anal cancer is a rare disease, which might be the reason for “one size fits all” approach still used radiotherapy target contouring. To refine and individualize future guidelines, detailed contemporary pattern of recurrence studies are needed. Methods Consecutive anal patients, all treated with curative intent intensity-modulated (IMRT), were retrospectively studied ( n = 170). Data was extracted from medical records radiological images. Radiotherapy planning CT’s...

Pluvial flood damage to residential buildings causes a significant part of direct tangible losses. In this study, we investigate the non-hazard variables and sewer system types in relation costs city Malmö, Sweden. A comprehensive data set around 1000 records from cloudburst event on 31 August 2014 Sweden has been analysed at property scale with no lumping together data. The results show that properties connected combined systems are much more exposed pluvial than separated systems, ratio...

Hydropower is a renewable energy that expected to be affected by persistent climate change in Mozambique. Variability of e.g. temperature and precipitation will contributors future shortage from production especially for hydropower biomass. This research reviews the impacts on productions Furthermore, statistical methods using regressions analysis was used evaluate scenario. The result showed average first 10 years 25.4°C last 26.3°C; this means gradient 0.88°C. increasing significant...

Abstract The force‐velocity relationship was determined at the moment of isometric peak twitch force in rabbit papillary muscles using damped‐release technique described previously. analysis carried out each muscle two or three temperatures within range 22–338deg; C. experimental data were fitted with Hill's equation by means a computer program least squares method. Lowering temperature caused an increase (Po) and also, generaliy, extrapolated value V max (the shortening velocity zero load)....

Abstract Stiffness determinations were made on rabbit papillary muscles at different lengths. Both in resting preparations and contracting lengths, where force was very low compared with active force, the stiffness increased recti‐linearly force. At any level, of a preparation greater rest than during activity.—Force‐velocity curves determined muscle lengths and, when necessary, data for whole corrected influence parallel elasticity order to derive force‐velocity contractile element alone. V...

Abstract The time course of the active state, force‐velocity relationship and series compliance rabbit papillary muscles were studied at different inotropic states produced by altered pacing within range 18 to 72 stimulations per minute. intervention a shift curve, without markedly changing shape suggesting that V max , capacity produce motion, P tension, affected same degree. Intensification state in response an increase stimulation frequency was associated with steeper rise earlier...

Abstract E dman , K. A. P. and E. N ilsson . The mechanical parameters of myocardial contraction studied at a constant length the contractile element Acta physiol. scand. 1968. 72 205–219. time course active state, force‐velocity relation series compliance were investigated in isolated papillary muscles rabbit.—The curve defined precise state given after stimulus could be fitted by Hill's equation. shape remained during activity period, indicating that ability to produce motion tension...

Phototoxicity of leaf extracts nine subspecies Heracleum sphondylium lat. was tested using Candida albicans is a test organism and the results were roughly quantified. The leaves sibircum usually non-phototoxic. Variation observed within granatense ternatum. alpinum, transsilvanicum, pyre-naicum, montanum orsinii moderately to strongly phototoxic. Morphologically variable populations varied correspondingly in degree phototoxicity. Fruits phototoxic all taxa studied roots but subsp. alpinum....

The purpose of this study is to present and analyze previously unpublished quantitative agricultural data for the area on shores Lake Chad in Chad, explore its relations hydro-climatic factors (lake levels, rainfall temperature). This a rural with livelihoods based agropastoral fishing activities, which are directly dependent region's high-varying hydro-climate. By using regression analysis from 1988 2012 was able establish correlations between latter output. These were used build...

Abstract The influence of temperature on the time course mechanical activity was investigated in isolated papillary muscles rabbit. By using “damped release” technique curves were determined terms velocity shortening contractile unit at a constant length. At any temperatures studied, exhibited slow onset and did not form distinct plateau. low contraction frequencies normal (2 mM) calcium concentration lowering from 32.5 to 26.5°C markedly affect rate development but increased peak amplitude...

In the BRCAsearch study, unselected breast cancer patients were prospectively offered germline BRCA1/2 mutation testing through a simplified procedure. The purpose of present study was to evaluate satisfaction with procedure and, furthermore, report on uptake rates prophylactic surgeries among carriers. Pre-test information provided by standardized invitation letter instead in-person genetic counseling. contact counselor for telephone counseling if they felt need that. Mutation carriers...

Exhaled breath temperature has been suggested to reflect airway inflammation, and it would be plausible measure the peripheral as a correlate inflammation. This study aims explore relative in patients with asthma, chronic obstructive pulmonary disease (COPD) or systemic sclerosis (SSc) compared healthy controls, relate lung function exhaled nitric oxide.Sixty-five subjects (16 asthmatics, 18 COPD patients, 17 SSc 14 subjects) performed fractional measurements using novel device, NO...