A5025336524- Cancer survivorship and care
- Breast Implant and Reconstruction
- Cutaneous Melanoma Detection and Management
- Breast Cancer Treatment Studies
- BRCA gene mutations in cancer
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer Treatment and Pharmacology
- Health Systems, Economic Evaluations, Quality of Life
- Family Support in Illness
- Cancer-related cognitive impairment studies
- Skin Protection and Aging
- Patient-Provider Communication in Healthcare
- Reconstructive Surgery and Microvascular Techniques
- Global Cancer Incidence and Screening
- Childhood Cancer Survivors' Quality of Life
- HER2/EGFR in Cancer Research
- Allergic Rhinitis and Sensitization
- Palliative Care and End-of-Life Issues
- Advanced Radiotherapy Techniques
- Behavioral Health and Interventions
- Ethics in Clinical Research
- Body Image and Dysmorphia Studies
- Erythropoietin and Anemia Treatment
- Lymphatic System and Diseases
Karolinska Institutet
2016-2025
Karolinska University Hospital
2010-2022
Skåne University Hospital
2010-2017
Lund University
2010-2017
Universität Innsbruck
2013
Innsbruck Medical University
2013
Ghent University Hospital
2013
Fondazione IRCCS Istituto Nazionale dei Tumori
2013
Sophiahemmet Hospital
1993-2012
UNSW Sydney
2010
There is increasing recognition of mindfulness and training as a way to decrease stress increase psychological functioning.The aims this study were examine the effects reduction on perceived well-being if changes in mediate intervention these outcomes.Seventy women one man with previous cancer diagnosis (mean age 51.8 years, standard deviation = 9.86) randomized into an group or wait-list control group. The consisted 8-week course.Compared participants group, had significantly decreased...
PURPOSE: To investigate the effect of recombinant human erythropoietin (epoetin beta) on anemia, transfusion need, and quality life (QOL) in severely anemic patients with low-grade non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), or multiple myeloma (MM). PATIENTS AND METHODS: Transfusion-dependent NHL (n = 106), CLL 126), MM 117) a low serum concentration were randomized to receive epoetin beta 150 IU/kg placebo subcutaneously three times week for 16 weeks. Primary efficacy...
To prospectively evaluate body image, sexuality, emotional reactions (anxiety, depression), and quality of life in a sample women having increased risk for breast cancer before 6 months 1 year after bilateral prophylactic mastectomy (BPM), to compare preoperative expectations the operation with postoperative concerning impact on six areas women's lives.A total 90 98 consecutive who underwent BPM during October 1997 December 2005 were included. Data collected by self-administered...
Mastectomy due to breast cancer is associated with chronic pain and a negative impact on sexuality. The purposes of the study were analyze prevalence discomfort in breasts, sexuality, quality life, feelings regret after bilateral prophylactic mastectomy immediate reconstruction implants.Fifty-nine women operated 2004-2006 included. A questionnaire was sent out two years procedure. Complications re-operations recorded.Mean follow-up time 29 months. 93% patients answered questionnaire. 69%...
<h3>Importance</h3> Standard dosing of chemotherapy based on body surface area results in marked interpatient variation pharmacokinetics, toxic effects, and efficacy. Whether tailored can improve outcomes is unknown, as the role dose-dense adjuvant chemotherapy. <h3>Objective</h3> To determine whether improves early breast cancer compared with a standard 3-weekly schedule. <h3>Design, Setting, Participants</h3> A randomized, open-label, phase 3 trial women aged 65 years younger who had...
The objective of this study was to assess health status and quality life in macromastia patients undergoing reduction mammaplasty. From January 1997 June 1997, the Department Reconstructive Plastic Surgery, at Stockholm Söder Hospital/Karolinska Hospital, conducted a prospective questionnaire with preoperative postoperative (6 12 months) assessments 49 women who were 20 years or older. included four parts: Part I assessed pain (scale 1 10) neck, shoulders, back, breast, bra strap indention,...
During the last 30 years, many methods for delayed breast reconstruction have been described. There is a lack of prospective randomized trials comparing methods. The present study (SVEA), conducted 1995 to 1996, describes impacts three methods: lateral thoracodorsal flap, latissimus dorsi and pedicled transverse rectus abdominis muscle flap (TRAM), on important areas life, patients' perception cosmetic result, quality life. Questionnaires were completed before randomization at 6 12 months...
The incidence of melanoma continues to increase in many countries, and primary prevention includes avoidance sunburn as well adequate sun protection behavior. aim this study was examine the prevalence self-reported behaviors users Internet, identify demographic, clinical, attitudinal/motivational correlates behaviors.Self-report data were gathered on behalf GenoMEL consortium using an online survey available 10 different languages, 8,178 individuals successfully completed at least 80% items,...
Conventional interferon-alpha (IFN) is an effective treatment for patients with myeloproliferative disorders. However, many discontinue therapy because of side effects.In this 24-month, Phase II feasibility study pegylated interferon alpha-2b (PEG-IFN) treatment, a starting dose 0.5 microg/kg per week was received by 21 polycythemia vera (PV) and essential thrombocythemia (ET). The objective, complete platelet response (CR), count<400x10(9)/L in symptomatic <600 asymptomatic patients....
We and others have recently shown that tumor characteristics are altered throughout progression. These findings emphasize the need for re-examination of at relapse led to recommendations from ESMO Swedish Breast Cancer group. Here, we aim determine whether molecular subtypes in breast cancer metastases confer clinically relevant prognostic information patients.
As patient assessment of health-related quality life (HRQOL) in cancer clinical trials has increased over the years, so need to attach meaningful interpretations differences HRQOL scores between groups and changes within groups. Determining what represents a minimally important difference (MID) is useful clinicians, patients researchers, can be used as benchmark for assessing success healthcare intervention. Our objective provide an evidence-based protocol determine MIDs European...
<h3>Importance</h3> Trastuzumab emtansine (T-DM1) is presently approved for treatment of advanced breast cancer and after incomplete response to neoadjuvant therapy, but the potential T-DM1 as monotherapy so far unknown. <h3>Objective</h3> To assess pathologic complete (pCR) standard therapy combination docetaxel, trastuzumab, pertuzumab (DTP) vs in patients with ERBB2 (formerly HER2)-positive cancer. <h3>Design, Setting, Participants</h3> This randomized phase 2 trial, conducted at 9 sites...
Breast reconstructions after breast cancer surgery are primarily performed to improve patients' quality of life. This study was investigate satisfaction with reconstruction and life pedicled or free transverse rectus abdominis musculocutaneous (TRAM) flap evaluate the aesthetic result both objectively subjectively. Sixty-three patients (36 flaps 27 TRAM flaps) answered two questionnaires; this group, 53 (27 26 participated in an evaluation. The questionnaires consisted parts: one...
Abstract The HAD scale was used to assess anxiety and depressive symptoms in three groups of individuals visiting an oncology clinic, healthy persons with hereditary melanoma (group DNS), patients treated for cutaneous malignant stage I MM1), generalized disease MM2). No differences were found on the subscale, although MM2 scored higher than other two out seven items. depression six items this subscale showed scores groups. In group as compared groups, there a proportion scoring above...
In a prospective, randomized study, an individual psychosocial support intervention performed by specially trained oncology nurses, or psychologists, were compared with standard care. Consecutive primary breast cancer patients about to start adjuvant therapy (n = 179) included. Data supplied the questionnaires European Organisation for Research and Treatment of Cancer Quality Life Study Group Core life questionnaire 30 questions (EORTC QLQ-C30) Breast Module 23 (BR23), Hospital Anxiety...
Background. Treatment of localized prostate cancer (PC) is controversial. This the first randomized study comparing an open surgery procedure (radical prostatectomy) with a combination high-dose rate brachytherapy (2 × 10 Gy) and external beam radiotherapy (25 2 in PC patients Sweden 1996–2001. The two randomization arms were compared regarding differences patients-reported outcomes, such as complications health-related quality life (HRQoL).