- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Voice and Speech Disorders
- Sleep and Wakefulness Research
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Cardiovascular Syncope and Autonomic Disorders
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Respiratory and Cough-Related Research
- Biomedical and Chemical Research
- Sleep and related disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Olfactory and Sensory Function Studies
- Speech and Audio Processing
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Nasal Surgery and Airway Studies
- Vagus Nerve Stimulation Research
- Salivary Gland Tumors Diagnosis and Treatment
- Music and Audio Processing
- Salivary Gland Disorders and Functions
- Cardiovascular and Diving-Related Complications
- Music Therapy and Health
- Neonatal and fetal brain pathology
Technical University of Munich
2016-2025
Klinikum rechts der Isar
2016-2025
University of Antwerp
2024-2025
Schön Klinik Bad Aibling
2024-2025
München Klinik
2016-2024
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2015-2023
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2014-2019
Universitäts-HNO-Klinik Heidelberg
2018-2019
Université de Bordeaux
2018
Centre Hospitalier Universitaire de Bordeaux
2018
Objective/Hypothesis The ADHERE Registry is a multicenter prospective observational study following outcomes of upper airway stimulation (UAS) therapy in patients who have failed continuous positive pressure for obstructive sleep apnea (OSA). aim this registry and purpose article were to examine the receiving UAS treatment OSA. Study Design Cohort Study. Methods Demographic data collection occurred at baseline, implantation visit, post‐titration (6 months), final visit (12 months). Patient...
Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep apnoea. The aim this study was identify predictors UAS therapy response in an international multicentre registry. Patients who underwent implantation the United States and Germany were enrolled observational Data collected included patient characteristics, apnoea/hypopnoea index (AHI), Epworth sleepiness scale (ESS), objective adherence, adverse events satisfaction measures. Post hoc univariate multiple...
The INTERSPEECH 2017 Computational Paralinguistics Challenge addresses three different problems for the first time in research competition under well-defined conditions: In Addressee sub-challenge, it has to be determined whether speech produced by an adult is directed towards another or a child; Cold cold told apart from 'healthy' speech; and Snoring four types of snoring have classified.In this paper, we describe these sub-challenges, their conditions, baseline feature extraction...
Objective/Hypothesis Upper airway stimulation (UAS) of the hypoglossal nerve has been implemented in routine clinical practice for patients with moderate‐to‐severe obstructive sleep apnea (OSA) who could not adhere to continuous positive pressure. This study reports objective and patient‐reported outcome after 12 months implantation. Study Design Multicenter prospective single‐arm study. Methods Consecutive received UAS system (Inspire Medical Systems, Inc., Minneapolis, Minnesota, Maple...
Objectives/Hypothesis Selective upper airway stimulation (sUAS) of the hypoglossal nerve is a useful therapy to treat patients with obstructive sleep apnea. Is it known that multiple obstructions can be solved by this technique, even at retropalatal region. The aim study was verify palatoglossus coupling soft palate during stimulation. Study Design Single‐center, prospective clinical trail. Methods Twenty who received an sUAS implant from April 2015 2016 were included. A drug‐induced sedated...
Objective Upper airway stimulation (UAS) is an alternative treatment option for patients unable to tolerate continuous positive pressure (CPAP) the of obstructive sleep apnea (OSA). Studies support safety and efficacy this therapy. The aim registry collect retrospective prospective objective subjective outcome measures across multiple institutions in United States Germany. To date, it represents largest cohort studied with Study Design Retrospective study. Setting Ten tertiary care hospitals...
To determine the association between findings of blinded reviews preoperative drug-induced sleep endoscopy (DISE) and outcomes hypoglossal nerve stimulation (HNS) for obstructive apnea (OSA).Cohort study.A retrospective, multicenter cohort study 343 adults who underwent treatment OSA with HNS from 10 academic medical centers was performed. Preoperative DISE videos were scored by four reviewers using VOTE Classification evaluation a possible primary structure contributing to airway...
Objective Selective stimulation of the hypoglossal nerve is a new surgical therapy for obstructive sleep apnea, with proven efficacy in well‐designed clinical trials. The aim study to obtain additional safety and data on use selective upper airway during daily routine. Study Design Prospective single‐arm study. Setting Three tertiary hospitals Germany (Munich, Mannheim, Lübeck). Subjects Methods A multicenter prospective under common implant follow‐up protocol took place 3 German centers...
Objective/Hypothesis Selective stimulation of the upper airway is a new therapy for obstructive sleep apnea. The aim study was to determine if selective nerve integrity monitoring (NIM) system could aid in precise placement cuff electrode upper‐airway stimulation. Study Design Single‐center, prospective clinical trial. Methods Twenty patients who received (Inspire Medical Systems, Maple Grove, MN) were implanted by using NIM system. tongue motions recorded during surgery and 2 months...
Obstructive sleep apnea (OSA) is a very common disorder (prevalence 2-7% in women, 7-14% men). It impairs the quality of life and increases mortality. Conservative treatment with continuous positive airway pressure highly effective, but patient compliance variable. Surgical treatments are controversial, as only few supported by evidence from controlled clinical trials. Adult patients OSA, CPAP intolerance, oropharyngeal obstruction were included trial. All underwent polysomnography (PSG)...
Obstructive sleep apnea (OSA) is a serious chronic disease and risk factor for cardiovascular diseases. Snoring typical symptom of OSA patients. Knowledge the origin obstruction vibration within upper airways essential targeted surgical approach. Aim this paper to systematically compare different acoustic features, classifiers their performance in classification excitation location snore sounds.Snore sounds from 40 male patients have been recorded during drug-induced endoscopy, categorized...
Seeking consensus on definitions and diagnosis of snoring obstructive sleep apnea (OSA) among surgeons is important, particularly in this relatively new field with variability knowledge practices. A set statements was developed based the literature circulated eight panel members European experts, utilizing Delphi method. Responses agreement disagreement each statement comments were used to assess level develop a revised version. The version anonymized sent member as second round. This...
Objectives/Hypothesis Upper airway stimulation (UAS) is an effective treatment for obstructive sleep apnea (OSA). Previous data have demonstrated a correlation between the phenotype of tongue motion and therapy response. Closed loop hypoglossal nerve implant offers five different electrode configuration settings which may result in motion. Study Design Two‐center, prospective consecutive trial university hospital setting. Methods Clinical outcomes 35 patients were analyzed after at least 12...
Objectives/Hypothesis To provide the ADHERE registry Upper Airway Stimulation (UAS) outcomes update, including analyses grouped by body mass index (BMI) and therapy discomfort. Study Design Prospective observational study. Methods captures UAS apnea‐hypopnea (AHI), Epworth sleepiness scale (ESS), usage, patient satisfaction, clinician assessment, safety over a 1‐year period. BMI ≤32 kg/m 2 (BMI 32 ) < ≤35 35 group were examined. Results One thousand eight hundred forty‐nine patients...