- Cardiac Health and Mental Health
- Chronic Disease Management Strategies
- Musculoskeletal pain and rehabilitation
- Mental Health Treatment and Access
- Diabetes Management and Education
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health, psychology, and well-being
- Schizophrenia research and treatment
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and Mental Health
- Mindfulness and Compassion Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Dementia and Cognitive Impairment Research
- Heart Failure Treatment and Management
- Long-Term Effects of COVID-19
- Diabetes Management and Research
- Mental Health and Psychiatry
- Heart Rate Variability and Autonomic Control
- Psychosomatic Disorders and Their Treatments
- Pain Management and Placebo Effect
- Treatment of Major Depression
- Pain Mechanisms and Treatments
- Geriatric Care and Nursing Homes
- Health and Wellbeing Research
- Digital Mental Health Interventions
University of Exeter
2014-2024
University of London
2024
London School of Hygiene & Tropical Medicine
2024
National Institute for Health Research
2011-2023
University of Birmingham
2023
University of Leicester
2023
Collaborative Group (United States)
2023
Restore America's Estuaries
2023
NIHR Leicester Biomedical Research Centre
2023
University Hospitals of Leicester NHS Trust
2023
A revision of the 2008 British Association for Psychopharmacology evidence-based guidelines treating depressive disorders with antidepressants was undertaken in order to incorporate new evidence and update recommendations where appropriate. consensus meeting involving experts their management held September 2012. Key areas depression were reviewed strength clinical implications considered. The then revised after extensive feedback from participants interested parties. literature review is...
Objective . Chronic widespread pain (CWP) is strongly associated with psychosocial distress both in a clinical setting and the community. The aim of this study was to determine contribution measures distress, health-seeking behaviour, sleep problems traumatic life events development new cases CWP Methods In population-based prospective study, 3171 adults aged 25–65 yrs free were followed-up 15 months later identify those CWP. Baseline data available on their scores from number psychological...
Background UK Biobank is a well-characterised cohort of over 500 000 participants including genetics, environmental data and imaging. An online mental health questionnaire was designed for to expand its potential. Aims Describe the development, implementation results this questionnaire. Method expert working group questionnaire, using established measures where possible, consulting patient group. Operational criteria were agreed defining likely disorder risk states, lifetime depression,...
<b>Objective</b> To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. <b>Design</b> Cluster randomised controlled trial. <b>Setting</b> 36 general practices in north west England. <b>Participants</b> 387 patients a record diabetes or heart disease, both, who had depressive symptoms (≥10 on patient health questionaire-9 (PHQ-9)) at least two weeks. Mean age was 58.5 (SD 11.7). Participants reported mean 6.2 3.0)...
Background UK Biobank is a well-characterised cohort of over 500 000 participants that offers unique opportunities to investigate multiple diseases and risk factors. Aims An online mental health questionnaire completed by was expected expand the potential for research into disorders. Method expert working group designed questionnaire, using established measures where possible, consulting with patient regarding acceptability. Case definitions were defined operational criteria lifetime...
Objectives To determine whether (i) motivational enhancement therapy (MET) + cognitive behaviour (CBT) compared with usual care, (ii) MET (iii) or CBT was more effective in improving glycaemic control when delivered by general nurses additional training these techniques. Design A three-arm parallel randomised controlled trial as the gold standard design to test effectiveness of psychological treatments. Setting The recruiting centres were diabetes clinics seven acute trusts south-east London...
To test the hypothesis that abnormalities in hypothalamic-pituitary-adrenal (HPA) stress-response system would act as an effect moderator between HPA function and onset of chronic widespread pain (CWP).We conducted a population-based prospective cohort study. Current psychosocial status were ascertained 11,000 subjects. Of 768 eligible subjects free CWP but at future risk based on their profile, 463 randomly selected, 267 (57.7%) consented to assessment axis function. Diurnal was measured by...
Psychological and social factors have been shown, separately, to predict outcome in individuals with chronic low back pain. Few previous studies, however, integrated both psychological factors, using prospective study of clinic populations pain patients, identify which are the most important targets for treatment. One hundred eight patients pain, newly referred an orthopaedic outpatient clinic, completed assessments demographic characteristics, details measures anxiety depression (Hospital...
Abstract In clinic studies, altered hypothalamic-pituitary-adrenal (HPA) axis function has been associated with fibromyalgia, a syndrome characterised by chronic widespread body pain. These results may be explained the high rates of psychological distress and somatisation. We address hypothesis that latter, rather than pain, might explain HPA results. A population study ascertained pain status in subjects aged 25 to 65 years. Random samples were selected from following three groups:...
Background. Primary care professionals often manage patients with multiple long-term health conditions, but managing multimorbidity is challenging given time and resource constraints interactions between conditions. Objective. To explore GP nurse perceptions of the influence on service organization clinical decision making. Methods. A qualitative interview study primary in practices Greater Manchester, UK. Interviews were conducted 15 GPs 10 practice nurses. Results. identified tensions...
To determine the relative contributions of psychological factors and sleep disturbance to reduced pain threshold we conducted a cross-sectional two-phase population-based study. A total 424 subjects were recruited, stratified by distress status. Subjects completed postal questionnaire that asked about current covered aspects status disturbance. Samples extent bodily they reported invited participate in an examination threshold. The association between status, low was examined using ordinal...
Poor sleep is associated with chronic widespread pain (CWP). Conversely, good-quality may play a role in the resolution of symptoms. Sleep multidimensional construct, comprising number diverse components. The aims current study were to examine hypotheses that: (i) good quality would predict CWP, (ii) restorative CWP and (iii) that these relationships be independent confounding psychological factors.Subjects population-based prospective completed questionnaire at baseline from which subjects...
The risk of depression is increased in people with long term conditions (LTCs) and associated poorer patient outcomes for both the depressive illness LTC, but often remains undetected poorly managed. aim this study was to identify explore barriers detecting managing primary care two exemplar LTCs: diabetes coronary heart disease (CHD). Qualitative in-depth interviews were conducted 19 healthcare professionals drawn predominately from care, along 7 service users 3 carers (n = 29). One focus...
Individuals with "insecure" adult attachment styles have been shown to experience more pain than people secure attachment, though results of previous studies inconsistent. We performed a cross-sectional study on large population-based sample investigate whether, compared free individuals, subjects chronic widespread were likely report insecure style. Subjects in completed self-rated assessment Attachment style was categorised as (i.e., normal style); or preoccupied, dismissing fearful...