Nicola Decaro

ORCID: 0000-0001-6348-7969
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About
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Research Areas
  • Animal Virus Infections Studies
  • Virus-based gene therapy research
  • Viral gastroenteritis research and epidemiology
  • Parvovirus B19 Infection Studies
  • SARS-CoV-2 and COVID-19 Research
  • Animal Disease Management and Epidemiology
  • Vector-Borne Animal Diseases
  • Viral Infections and Immunology Research
  • Herpesvirus Infections and Treatments
  • SARS-CoV-2 detection and testing
  • Viral Infections and Vectors
  • Virology and Viral Diseases
  • COVID-19 Clinical Research Studies
  • Microbial infections and disease research
  • Rabies epidemiology and control
  • Hepatitis B Virus Studies
  • Respiratory viral infections research
  • Vector-borne infectious diseases
  • Hepatitis C virus research
  • Congenital Anomalies and Fetal Surgery
  • T-cell and Retrovirus Studies
  • Viral-associated cancers and disorders
  • Cytomegalovirus and herpesvirus research
  • Hepatitis Viruses Studies and Epidemiology
  • Bartonella species infections research

University of Bari Aldo Moro
2016-2025

Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2022

National Research Centre
2022

Istituto Zooprofilattico Sperimentale del Mezzogiorno
2022

University of Turin
2021

University of Veterinary Medicine
2019

Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata
2014-2018

Hungarian Academy of Sciences
2011-2018

University of Teramo
2015

The Ohio State University
2015

Two isolates of canine parvovirus (CPV) were obtained from dogs affected with severe haemorrhagic diarrhoea. Type 2b antigenic specificity was predicted by both analysis monoclonal antibodies and PCR characterization type-specific primers. Nevertheless, sequence the capsid protein-encoding gene revealed two amino acid changes. One changes position 426 (Asp to Glu), in a major site viral capsid, determining replacement residue unique CPV type 2b. The failure established typing methods...

10.1099/0022-1317-82-12-3021 article EN Journal of General Virology 2001-12-01

Abstract SARS-CoV-2 emerged from animals and is now easily transmitted between people. Sporadic detection of natural cases in alongside successful experimental infections pets, such as cats, ferrets dogs, raises questions about the susceptibility under conditions pet ownership. Here, we report a large-scale study to assess infection 919 companion living northern Italy, sampled at time frequent human infection. No tested PCR positive. However, 3.3% dogs 5.8% cats had measurable neutralizing...

10.1038/s41467-020-20097-0 article EN cc-by Nature Communications 2020-12-04

Abstract Canine coronavirus (CCoV) is usually responsible for mild, self-limiting infections restricted to the enteric tract. We report an outbreak of fatal disease in puppies caused by a pathogenic variant CCoV that was isolated from organs with severe lesions.

10.3201/eid1203.050839 article EN cc-by Emerging infectious diseases 2006-03-01

Severe acute respiratory syndrome (SARS) is a newly emerging, highly transmissible and fatal disease caused by previously unknown coronavirus (SARS-CoV). Existing in non-identified animal reservoirs, SARS-CoV continues to represent threat humans because there no effective specific antiviral therapy for infections. Objectives Starting from the observation that cyclopentenone cyclooxygenase (COX) metabolites are active against several RNA viruses, we investigated effect of COX inhibitor...

10.1177/135965350601100803 article EN Antiviral Therapy 2006-11-01

Canine parvovirus (CPV), which causes hemorrhagic enteritis in dogs, has 3 antigenic variants: types 2a, 2b, and 2c. Molecular method assessment of the distribution CPV variants Europe showed that new variant CPV-2c is widespread viruses are distributed different countries.

10.3201/eid1308.070505 article EN cc-by Emerging infectious diseases 2007-08-01

Canine parvovirus (CPV) type 2 (CPV-2) emerged around 1978 as a major pathogen of dogs worldwide. In the mid-1980s, original CPV-2 had evolved and was completely replaced by variants, CPV-2a CPV-2b. 2000, new variant CPV (named CPV-2c) detected in Italy now cocirculates with types 2a 2b that country. The CPV-2c has also been reported from single outbreaks Vietnam Spain. This study conducted to determine if occurs United States. Thirty-three fecal samples were collected 16 states between...

10.1177/104063870701900512 article EN Journal of Veterinary Diagnostic Investigation 2007-09-01

Abstract We identified a novel calicivirus in pup with enteritis. The isolate was related genetically (90.1% aa identity the capsid protein) to lion norovirus strain.

10.3201/eid1408.080062 article EN cc-by Emerging infectious diseases 2008-08-01

Four canine coronavirus type II (CCoV-II) strains were identified in the guts and internal organs of pups which had died acute gastroenteritis. The CCoV-II strictly related to porcine transmissible gastroenteritis virus (TGEV) N-terminal domain spike protein, whereas other parts genome, a higher genetic relatedness recent isolates was observed. Experimental infection dogs with TGEV-like isolate induced mild without any systemic involvement. By neutralization tests, antigenic differences...

10.1128/jvi.01937-08 article EN Journal of Virology 2008-11-27

Abstract In 2010, a HoBi-like pestivirus was isolated from clinically affected calves in Italy. This European virus reproduced milder form of disease under experimental conditions and genetically related to previously reported strains. Isolation this novel clinical outbreak may have implications for cattle health prophylactic programs.

10.3201/eid1708.101447 article EN cc-by Emerging infectious diseases 2011-07-25

SARS-CoV-2 originated in animals and is now easily transmitted between people. Sporadic detection of natural cases alongside successful experimental infections pets, such as cats, ferrets dogs, raises questions about the susceptibility under conditions pet ownership. Here we report a large-scale study to assess infection 817 companion living northern Italy, sampled at time frequent human infection. No tested PCR positive. However, 3.4% dogs 3.9% cats had measurable neutralizing antibody...

10.1101/2020.07.21.214346 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-07-21

OPINION article Front. Vet. Sci., 10 February 2021Sec. Veterinary Experimental and Diagnostic Pathology Volume 8 - 2021 | https://doi.org/10.3389/fvets.2021.619207

10.3389/fvets.2021.619207 article EN cc-by Frontiers in Veterinary Science 2021-02-10
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