A5022795469- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Sleep and related disorders
- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Head and Neck Surgical Oncology
- Dementia and Cognitive Impairment Research
- Neurosurgical Procedures and Complications
- Pituitary Gland Disorders and Treatments
- Traumatic Brain Injury Research
- Intracranial Aneurysms: Treatment and Complications
- Spinal Dysraphism and Malformations
- Sleep and Wakefulness Research
- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurofibromatosis and Schwannoma Cases
- Surgical Simulation and Training
- Cardiac Arrest and Resuscitation
- Anatomy and Medical Technology
- Diversity and Career in Medicine
- Trauma and Emergency Care Studies
- Sleep and Work-Related Fatigue
- COVID-19 Impact on Reproduction
- Moyamoya disease diagnosis and treatment
New York University
2023-2025
Neurological Surgery
2023-2024
NYU Langone Health
2023-2024
Hinge Health
2024
Fundación Universitaria de Ciencias de la Salud
2024
Mayo Clinic in Florida
2022-2023
WinnMed
2022-2023
Universidad de Los Andes
2018-2023
Jacksonville College
2022
Universidad de Los Andes
2020
Traumatic Brain Injury (TBI) remains a leading cause of morbidity and mortality among all ages; despite the advances, understanding pathophysiological responses after TBI is still complex, involving multiple mechanisms. Previous reviews have focused on potential targets; however, research targets has continuously grown in last five years, bringing even more alternatives elucidating previous Knowing key updated pathophysiology concepts vital for adequate management better outcomes. This...
Abstract Background An elevated neutrophil–lymphocyte ratio (NLR) in blood has been associated with Alzheimer’s disease (AD). However, an NLR also implicated many other conditions that are risk factors for AD, prompting investigation into whether the is directly linked AD pathology or a result of underlying comorbidities. Herein, we explored relationship between and biomarkers cerebrospinal fluid (CSF) cognitively unimpaired (CU) subjects. Adjusting sociodemographics, APOE4, common...
Previous studies have shown low rupture rates for small aneurysms (<10 mm), suggesting that the risk of treatment could exceed benefits. However, evidence has changed, showing crescent aneurysmal subarachnoid hemorrhage (aSAH) associated with aneurysms. We report trends in size, localization, clinical characteristics, and outcomes intracranial (IAs).In this retrospective study, a total 200 histories patients diagnosed IAs over an 8-year period were analyzed. Variables considered included...
Background: Gliomas represent almost 30% of all primary brain tumors and account for 80% malignant ones. In the last two decades, significant progress has been made in understanding gliomas’ molecular origin development. These advancements have demonstrated a remarkable improvement classification systems based on mutational markers, which contribute paramount information addition to traditional histology-based classification. Methods: We performed narrative review literature including each...
Objetivo: presentar los avances diagnósticos, moleculares y radiológicos, así como en las estrategias terapéuticas para gliomas difusos últimos 5 años (2018-2023) la Fundación Universitaria de Ciencias Salud (FUCS), Bogotá D.C., Colombia. Materiales métodos: se describen técnicas diagnósticas utilizadas con casos ilustrativos. Resultados: muestran herramientas el manejo difusos. Discusión: ha avanzado clasificación, diagnóstico tratamiento difusos, gracias a tecnológicos marcadores...
Background: Decompressive craniectomy (DC) is a lifesaving procedure, relieving intracranial hypertension. Conventionally, DCs are performed by reverse question mark (RQM) incision. However, the use of L. G. Kempe’s (LGK) incision has increased in last decade. We aim to describe surgical nuances LGK and standard RQM incisions treat patients with severe traumatic brain injury (TBI), hemorrhage (ICH), empyema, malignant ischemic stroke. Furthermore, describe, limitations, wound healing,...
Traumatic Brain Injury (TBI) remains a leading cause of morbidity and mortality among all ages; despite the advances, understanding pathophysiological responses after TBI is still complex, involving multiple mechanisms. Previous reviews have focused on potential targets; however, research targets has continuously grown in last five years, bringing even more alternatives elucidating previous Knowing key updated pathophysiology concepts vital for adequate management better outcomes. This...
An elevated neutrophil-lymphocyte ratio (NLR) in blood has been associated with Alzheimer's disease (AD). However, an NLR also implicated many other conditions that are risk factors for AD, prompting investigation into whether the is directly linked AD pathology or a result of underlying comorbidities. Herein, we explored relationship between and biomarkers cerebrospinal fluid (CSF) cognitively unimpaired (CU) subjects. Adjusting sociodemographics, APOE4, common comorbidities, investigated...
INTRODUCTION: Invasion of the medial wall cavernous sinus (CS) by pituitary tumors is a factor associated with persistence disease and subtotal resection these tumors. Resection CSis therefore an option for maximum such tumors, however, there concern potential complications this technique at time, limited data available in literature. METHODS: Single center retrospective study evaluating patients that underwent endoscopic endonasal adenomas CS, between January 2022 February 2023. Extent...
INTRODUCTION: Clinical prognosis of patients with glioblastoma (GBM) is calculated clinical scores, extent resection, molecular markers, and tumor subtypes. However, these are often hampered by patient comorbidities, drug toxicity, other confounding factors. We designed a confined 3D microfluidic technology based on the brain cytoarchitecture mimicking diameters perivascular spaces white matter tracts utilized GBM to invade. METHODS: Patient-derived cell lines (n = 13) were obtained from...
Abstract Background Apolipoprotein (Apo) E4, a main susceptibility gene for Alzheimer’s disease (AD) is associated with increased vascular dysfunction, amyloid pathology, and neurodegeneration. The effector pathways leading to risk in ApoE4 carriers needs be established. Platelet aggregation key marker of dysfunction studies need examine whether relationship allele status platelet biology exists Method We examined cross‐sectional associations ApoE genotypes (E2 or E4 against E3, the most...
Abstract Background We examined racial differences between measures of limbic white matter tracts and objective sleep parameters in cognitively unimpaired older‐adults. Method This cross‐sectional study included 170 community‐dwelling older‐adults (mean±SD: age = 67.2±5.2y) participating NYU studies sleep, aging, memory. Subjects completed polysomnography (NPSG) brain MRI. Sleep interest total time (TST), NREM stages 2, 3 REM duration, latency fragmentation, slow spindles (SSP), spindle...
Abstract Background An elevated neutrophil‐lymphocyte ratio (NLR) has been associated with Alzheimer’s disease (AD). However, an NLR also implicated in many other conditions that are risk factors for AD, prompting investigation into whether the is directly linked AD pathology or a result of underlying comorbidities. Method We explored relationship between and biomarkers cerebrospinal fluid (CSF) cognitively unimpaired (CU) subjects. Adjusting sociodemographics, APOE4, common comorbidities,...
Abstract Background Obstructive sleep apnea (OSA) is a complex and heterogeneous condition associated with chronic physiological neuropsychological disturbances (1–4). One notable effect observed in OSA patients memory impairment (2,5). Additionally, some reports suggest that may be Alzheimer’s Disease (AD) (4). Memory consolidation regulated through cohesive network of structures, including the hippocampus, fornix, anterior thalamus, mammillary bodies (6). Diminished body hippocampal volume...
Abstract Background Microstructure impairments of the limbic tracts are seen in early stages Alzheimer’s disease (AD) continuum. Sleep disruptions differ between sexes and have been linked with AD. We examined sex differences measures white matter objective sleep parameters cognitively unimpaired older adults. Method This cross‐sectional study included 170 community‐dwelling adults (mean±SD: age=67.2±5.2y) participating NYU studies sleep, aging, memory. Subjects completed polysomnography...
Abstract Background Increased body mass index (BMI) in mid‐life is associated with a higher risk of Alzheimer’s disease (AD). Neurofibrillary tangles (NFTs), comprised hyperphosphorylated aggregated tau protein, are the pathological hallmark neurodegenerative tauopathies including Disease The relationship between sex‐dependent adiposity late adulthood and NFT pathology remain inconclusive. We examined sex differences BMI tau‐PET among cognitively normal individuals. Method This...