A5087872245- Mechanical Circulatory Support Devices
- Organ Transplantation Techniques and Outcomes
- Cardiac Valve Diseases and Treatments
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Acute Kidney Injury Research
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Cardiac and Coronary Surgery Techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Ischemia and Reperfusion
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Blood transfusion and management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pulmonary Hypertension Research and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Intramuscular injections and effects
- COVID-19 epidemiological studies
- Vascular Malformations Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Antimicrobial Resistance in Staphylococcus
Astana Medical University
2025
National Research Center for Maternal and Child Health
2022-2024
Cold storage preservation is the standard approach for heart transplantation but a time-limited method of care. Ex vivo perfusion expands donor pool due by mitigating time and distance barriers allows possibility to improve graft function. We report long term follow up successful following an ex 17 h using Organ Care System in patient with left ventricular assist device.
Background First reported case of Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) in Kazakhstan was identified March 2020. Many specialized tertiary hospitals including National Research Cardiac Surgery Center (NRCSC) were re-organized to accept disease 2019 (COVID-19) infected patients during summer months Although many studies from worldwide their experience treating with COVID-19, there are limited data available the Central Asia countries. The aim this study is...
The usage of cardiopulmonary bypass (CPB) in cardiothoracic surgery contributes to the activation inflammatory response. In certain cases, systemic response may be immoderate, leading organ dysfunction, such as acute renal failure or multiorgan dysfunction. This study aimed examine effect haemoadsorption (HA) therapy on markers and damage indices during early postoperative period. We conducted a retrospective analysis prospectively collected data single tertiary care center patients operated...
TAVR remains a complex procedure that may result in serious intraprocedural complications. In many of these circumstances, venoarterial extracorporeal membrane oxygenation (V-A ECMO) helps to manage complications, provides hemodynamic back-up, and bridges an emergency open heart surgery. The clinical outcomes 27 patients who underwent prophylactic implantation peripheral V-A ECMO (pV-A during high-risk transcatheter aortic valve replacement (TAVR) cases are described. From June 2012 October...
Generally, the dysfunction or failure of bioprosthetic heart valves (BHVs) is managed by replacement surgery. In case tricuspid valve dysfunction, re-do surgery rarely attempted because critically high risk developing pulmonary hypertension, embolism, and intraoperative mortality. Hence, transcatheter repair procedures are preferred. More recently, valve-in-valve (ViV) treatments have gained importance their less invasiveness, especially for patients with prior surgeries. Encouraging...
Cardiac surgery with cardiopulmonary bypass (CPB) is associated hypofibrinogenemia and severe bleeding requiring transfusion. Guidelines recommend cryoprecipitate or fibrinogen concentrate (FC) for the treatment of acquired hypofibrinogenemia. This study compared FC correction costs.
Abstract Background ECMO support is associated with the development of a systemic hyper-inflammatory response, which may become quite significant and extreme in some cases. We hypothesize that Cytosorb or Jafron therapy benefit patients on V-A terms levels inflammatory markers such as IL-6, complications, overall outcomes. Methods conducted retrospective study prospectively collected data single tertiary care center between January 2021 April 2022. At time analysis this article, 20 had...
Background. Pulmonary complications are the second most common complication after cardiac surgery with cardiopulmonary bypass. atelectasis can occur from various intraoperative causes such as prolonged operation, time of anaesthesia more than 3-4 hours, use a thoracic artery, bypass during surgery, lack ventilation, haemotransfusion 4 or units packed red blood cells in perioperative period. Impact mechanical venatilation still unknown. Methods. Prospective, randomised study at one centre....
Acute kidney injury (AKI) is a condition characterized by sudden decline in function, leading to accumulation of waste products and fluids the body. It common serious complication patients with cardiovascular diseases, it associated increased morbidity mortality.<br /> <br <b>Aim</b><br In this study, we explore relationship between cardiac issues development AKI, as well strategies for its prevention management. The primary aim study examine incidence risk factors...
Abstract Background and Aims Cardiac surgery is maintained by various complications. Major contribution associated with cardiopulmonary bypass (CBP). CPB provokes activation of the cascade mechanism inflammation releasing cytokines a systemic inflammatory response syndrome (SIRS). Activation contact system due to exposure artificial surface circuit blood cells, endotoxemia, ischemia reperfusion injury surgical trauma are all potential triggers following CPB. This reaction may leads...
■ ПЕРИОПЕРАЦИОННЫЕ ТЕХНОЛОГИИ Инфекционный эндокардит (ИЭ) связан с высоким уровнем смертности, чрезмерной системной гиперинфекционной реакцией или сепсисом.Лечение тяжелого ИЭ включает в себя комбинацию хирургического вмешательства и антибиотиков.Однако традиционной терапии может оказаться недостаточно для борьбы инфекцией.В последнее время гемадсорбция является многообещающей терапией лечения пациентов сепсисом.Этот метод все чаще используется предотвращения септических осложнений после...
Abstract BACKGROUND AND AIMS Complications after cardiac surgery have serious negative consequences, prolonging the average ICU stay days and costs. Prevention treatment of complications aortic valve replacement is a problem. According to numerous authors, incidence varies from 10 &gt;60% cases. Development associated with higher hospital mortality rate, risk infection more complex course disease. Advances in led reduction overall open-heart surgery; however, it can still exceed 40%...
Abstract BACKGROUND AND AIMS Chronic heart failure (CHF) in the terminal stage is a crucial issue of medicine. Heart transplantation still best treatment option. Lack donors, long waiting time make almost impossible. Implantation left ventricular assist device—LVAD) patients with CHF bridge to transplantation. Nevertheless, LVAD implantation procedure time-consuming, requires significant material costs, and leads numerous complications postoperative period. Acute kidney injury (AKI) one most...
Background: We report a case of successful heart transplantation following donor resuscitation after 7 hours cold storage using ongoing recipient's cardiopulmonary bypass circuit prior to organ implantation in patient with left ventricular assist device. Methods: The was on LVAD support as bridge transplantation. patient's clinical status complicated by driveline infection influenced his necessitating urgent time ischemic already 430 minutes. Due the high risk graft failure and...
This case report describes the history of a 62-year-old man with symptoms severe heart failure caused by critical mitral valve (MV) &nbsp;stenosis extremely enlarged left atrium (LA) and chronic rheumatic disease. The patient has had MV replacement, aortic (AoV) tricuspid (TV) plastic surgery, atrial thrombectomy, reduction, resection LA.<br /> operation was performed median sternotomy, in condition artificial blood circulation cannulation, separate cannulation Cava veins...
Abstract Background and Aims In the rapidly changing conditions of life due to COVID - 19 pandemic, medical society around world have faced with question treatment previously unknown, multi-faceted insidious infection. The coronavirus infection has forced doctors reconsider tactics intensive care patients in critical condition. To date, overall mortality rate from – varied 8.11 120.85 per 100.000 population (Johns Hopkins University analyses). Mortality extremely severe cases exceeds 60% 78%...