Charles C. Coddington

ORCID: 0000-0001-6450-8207
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Health and Technologies
  • Sperm and Testicular Function
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Gynecological conditions and treatments
  • Prenatal Screening and Diagnostics
  • Ectopic Pregnancy Diagnosis and Management
  • Ovarian cancer diagnosis and treatment
  • Reproductive System and Pregnancy
  • Maternal and Perinatal Health Interventions
  • Growth Hormone and Insulin-like Growth Factors
  • Intestinal and Peritoneal Adhesions
  • Reproductive Health and Contraception
  • Birth, Development, and Health
  • Thyroid Disorders and Treatments
  • Maternal and fetal healthcare
  • Estrogen and related hormone effects
  • Cancer Risks and Factors
  • Menopause: Health Impacts and Treatments
  • Ureteral procedures and complications
  • Reproductive Physiology in Livestock
  • Sexual Differentiation and Disorders

Carolinas Medical Center
2019-2024

WinnMed
2012-2023

Mayo Clinic in Florida
2009-2023

Atrium Medical Cente
2019-2022

Mayo Clinic in Arizona
2011-2021

Mayo Clinic
2012-2021

University of North Carolina at Charlotte
2020-2021

The Carolinas Center
2021

Community Link
2021

American Jewish Committee
2020

<b>Objective</b>&nbsp;To estimate the effectiveness and safety of thyroid hormone treatment among pregnant women with subclinical hypothyroidism. <b>Design</b>&nbsp;Retrospective cohort study. <b>Setting</b>&nbsp;Large US administrative database between 1 January 2010 31 December 2014. <b>Participants</b>&nbsp;5405 hypothyroidism, defined as untreated stimulating (TSH) concentration 2.5-10 mIU/L. <b>Exposure</b>&nbsp;Thyroid therapy. <b>Main outcome measure</b>&nbsp;Pregnancy loss other...

10.1136/bmj.i6865 article EN cc-by-nc BMJ 2017-01-25

Subclinical hypothyroidism (SCH) has been associated with increased risk of adverse pregnancy outcomes in some, but not all, studies. Uncertainty remains regarding the impact levothyroxine (LT4) therapy on improving health pregnant women SCH. The objective this study was to assess potential benefits LT4 SCH.The medical records were reviewed SCH, defined as an elevated serum thyrotropin (TSH) >2.5 mIU/L for 1st trimester or >3 2nd and 3rd trimesters, ≤10 mIU/L. Pregnant divided into two...

10.1089/thy.2016.0014 article EN Thyroid 2016-04-25

Adenomyosis is rarely diagnosed before hysterectomy and commonly coexists with uterine leiomyomas. The objective of this study was to identify distinct features a concurrent diagnosis adenomyosis in women leiomyomas.We conducted case-control undergoing histologic both leiomyomas but no adenomyosis. A retrospective medical record review hospital ambulatory records performed ascertain sociodemographic anthropometric variables, as well confirm intraoperative pathologic findings.Our sample...

10.1093/humrep/deq034 article EN Human Reproduction 2010-02-22

10.1016/j.fertnstert.2009.06.049 article EN publisher-specific-oa Fertility and Sterility 2009-07-31

Abstract Human oocytes were stored (25°C) in 1.5 M MgCl 2 for 6–30 days, then utilized the new hemizona assay (HZA) tight binding of human spermatozoa [Burkman et al.: Fertil Steril 49:688–697, 1988]. We have compared 1) ability matching salt‐treated hemizonae or dimethylsulfoxide (DMSO)‐treated to distinguish between sperm from semen having normal versus subnormal characteristics and, 2) kinetics fertile DMSO‐treated hemizonae. After preparation, one was incubated with and placed group. As...

10.1002/mrd.1120220103 article EN Gamete Research 1989-01-01

Do women with polycystic ovary syndrome (PCOS) have a greater risk of adverse pregnancy complications (gestational diabetes, preeclampsia, cesarean section, placental abnormalities) and neonatal outcomes (preterm birth, small for gestational age, prolonged delivery hospitalization) compared to without PCOS diagnosis does this vary by BMI, subfertility fertility treatment utilization?Deliveries history were at associated cardiometabolic function, including diabetes as well preterm birth...

10.1093/humrep/deac210 article EN Human Reproduction 2022-09-23

Background Polycystic ovary syndrome (PCOS) is characterized by a hyperandrogenic state and frequently develops skeletal muscle insulin resistance. We determined whether testosterone adversely affects action increasing serine phosphorylation of IRS-1636/639 in differentiated rat myotubes. The Akt, mTOR, S6K, downstream targets the PI3-kinase-IRS-1 complex were also studied. Methods Primary myotubes subjected to for 30 min after 16-hour pre-exposure either low (20 ng/ml) or high (200 doses...

10.1371/journal.pone.0004274 article EN cc-by PLoS ONE 2009-01-23
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