A5080224322- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Allergic Rhinitis and Sensitization
- Neuroscience of respiration and sleep
- Food Allergy and Anaphylaxis Research
- Respiratory viral infections research
- Viral Infections and Outbreaks Research
- Cardiac Arrest and Resuscitation
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Obstructive Sleep Apnea Research
- Pneumonia and Respiratory Infections
- Healthcare Systems and Practices
- Heart Rate Variability and Autonomic Control
- Histiocytic Disorders and Treatments
- Lung Cancer Diagnosis and Treatment
- Psychosomatic Disorders and Their Treatments
- Family and Patient Care in Intensive Care Units
- Emergency and Acute Care Studies
Centre Hospitalier Universitaire de Clermont-Ferrand
2022-2024
Centre Hospitalier Universitaire de Bordeaux
2024
Hôpital Cardiologique du Haut-Lévêque
2024
Inserm
2013-2023
Université Clermont Auvergne
2022-2023
Assistance Publique – Hôpitaux de Paris
2015-2023
Sorbonne Université
2014-2023
Neurophysiologie respiratoire expérimentale et clinique
2016-2023
Hôpital Tenon
2021-2023
Pitié-Salpêtrière Hospital
2016-2021
Patient-ventilator asynchrony is associated with a poorer outcome. The prevalence and severity of during the early phase weaning has never been specifically described. authors' first aim was to evaluate prognosis impact factors asynchrony. Their second compare according two methods detection: visual inspection signals computerized method integrating electromyographic activity diaphragm.This an ancillary study multicenter, randomized controlled trial comparing neurally adjusted ventilatory...
Atopic march refers to the typical transition from a food allergy in early childhood allergic asthma older children and adults. However precise interplay of events involving gut, skin pulmonary inflammation this process is not completely understood.To develop mouse model mixed respiratory mimicking atopic better understand impact allergies on asthma.Food ovalbumin (OVA) was induced through intra-peritoneal sensitization intra-gastric challenge, and/or house dust mite (HDM) obtained...
Background Allergic asthma is caused by abnormal immunoreactivity against allergens such as house dust mites among which Dermatophagoides farinae (Der f) a common species. Currently, immunotherapy based on allergen administration, has variable effect from patient to and may cause serious side effects, principally the sustained risk of anaphylaxis. DNA vaccination promising approach triggering specific immune response with reduced allergenicity. Objective The aim study evaluate effects...
Background Reduced exercise capacity severely impacts quality of life in pulmonary Langerhans cell histiocytosis. Ascertaining mechanisms that impair is necessary to identify targets for symptomatic treatments. Methods Dyspnea, function tests and cardiopulmonary test were analysed 62 study participants. Data compared between subjects with impaired normal aerobic (V’O2 peak less than 84% versus predicted or more). reduced using a principal component analysis. Multivariate analysis included...
Abstract Background and Objective Persistent dyspnoea is a public health issue for which the therapeutic arsenal limited. This study tested high‐flow nasal cannula therapy (HFNT) as means to alleviate experimental dyspnoea. Methods Thirty‐two healthy subjects underwent an induced by thoracoabdominal elastic loading. HFNT was administered with alternately FiO 2 of 100% (HFNT100) or 21% (HFNT21). The sensory (S‐VAS) affective (A‐VAS) components dyspnoea, transcutaneous CO pressure (PtcCO ),...
Rationale Breathing is a cyclic activity that variable by nature. variability modified in mechanically ventilated patients. We aimed to evaluate whether decreased on the day of transition from assist-control ventilation partial mode assistance was associated with poorer outcome. Methods This an ancillary study multicentre, randomised, controlled trial comparing neurally adjusted ventilatory assist pressure support ventilation. Flow and electrical diaphragm (EAdi) were recorded within 48 h...
Here, we aimed to assess the specific features of lung cancer in patients with long-term oxygen therapy (LTOT), and compare their outcomes suffering from without LTOT.This retrospective, case-controlled study included LTOT an incident diagnosis treated at Rouen University Hospital.Out 2201 LTOT, 31 were diagnosed cancer. Among 24 proven cancer, most frequent histological type was squamous cell carcinoma (n = 12/24, 50%). Active treatment any given 19/31 (61%) 41/62 (66%) control groups,...