- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Circular RNAs in diseases
- Cancer Immunotherapy and Biomarkers
- Genetic factors in colorectal cancer
- MicroRNA in disease regulation
- Cancer Treatment and Pharmacology
- Extracellular vesicles in disease
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Skin Protection and Aging
- CAR-T cell therapy research
- Pancreatic and Hepatic Oncology Research
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer-related molecular mechanisms research
- Multiple and Secondary Primary Cancers
- Cancer-related cognitive impairment studies
- Cancer, Hypoxia, and Metabolism
- Chemotherapy-induced cardiotoxicity and mitigation
- Inflammatory mediators and NSAID effects
- Cancer Genomics and Diagnostics
- Cancer Cells and Metastasis
- Virus-based gene therapy research
- RNA Interference and Gene Delivery
Institute of Oncology Prof. Dr. Ion Chiricuta
2014-2024
Iuliu Hațieganu University of Medicine and Pharmacy
2009-2024
Karolinska Institutet
2005
Due to the high death rate associated with gastric cancer, a great deal of research has been conducted on this disease. The goal paper was start trimestral review 2024 for year that had just started. scientific literature from 1 January chosen consideration guidelines European Society Medical Oncology (ESMO), which are updated new findings but not systematically reviewed annually. We used search term “gastric cancer” find most current publications in PubMed database related prognosis and...
MicroRNAs (miRNAs), a class of small non-coding RNAs represent potential biomarkers for colorectal cancer (CRC). The study hypothesized that miRNAs associated with liver metastases may also contribute to assessing treatment response when plasma exosomes. In this study, we used two sets biological samples, collection tumor tissues harvested from patients CRC and without metastases, FOLFOX4/FOLFIRI regimens. We investigated 10 target in the tissue 28 identified miR-125b-5p, miR-17-5p,...
Numerous studies have been performed on Helicobacter pylori infection because of the high death rate linked to this illness and gastric cancer. An update key developments in recent years investigation cancer is goal review. Using search term “Helicobacter pylori, cancer”, PubMed database was searched. Only papers published 2024 fulfilled inclusion criteria. Because case report were not part our investigation, they satisfied exclusion Most research variable genes guided by genetics determine...
The depletion of the ozone layer allows overexposure skin to UV radiation, which is prolonged due increasing life expectancy, together with inappropriate habits contribute incidence cutaneous malignancies. Plant extracts antioxidant capacities are frequently employed as a means protect against ultraviolet (UV) radiations, thus preventing cancers. In present study we assessed red grape seed extract (GSE) potential reduce B (UVB) radiation-induced reactive oxygen species (ROS) and subsequent...
Fluoropyrimidines represent the backbone of many chemotherapy protocols and standard treatment for types tumors. Toxicity associated with fluoropyrimidines can occur in up to 40% cases.The objective this study was analyze correlation between plasma concentration 5-fluorouracil adverse events that patients might experience during therapy.A total 58 received 5-fluorouracil-based chemotherapy. A blood sample collected from each patient drug infusion, order assess area under curve...
Lung cancer remains one of the leading causes cancer-related deaths worldwide. It is classified into two main histological groups: non-small cell lung (NSCLC) and small cancer. Improving outcome patients could be possible by enhancing early diagnosis. In current study, we evaluated levels three microRNAs - miR-21-5p, miR-155-5p, miR-181a-5p in tumor (TT) vs adjacent normal tissue (NT), as well their expression plasma extracellular vesicles (EVs) from squamous carcinoma (LUSC) male healthy...
Many studies on gastric cancer treatment have identified predictors of immunotherapy benefits. This article provides an update the major developments in research related to predictive factors for cancer. We used search term “predictive factors, immunotherapy, cancer” find most current publications PubMed database Programmed cell death, genetic, and immunological are main study topics immunotherapy’s Other preventive were also found, including clinical tumor microenvironment imaging...
Background: Colorectal cancer (CRC) represents a major public health problem owing to the fact that many patients are diagnosed in locally advanced or metastatic stage when chemotherapy is only remaining option. However, treatment response still unpredictable and depends upon diversity of factors such as tumor inherited acquired drug resistance host immune malignant cells. The aim this study was evaluate serum levels interleukin 6, 8, 10 (IL-6, 10) possible predictive for correlation between...