A5073697566- Diabetes and associated disorders
- Pancreatic function and diabetes
- Pharmacological Effects of Natural Compounds
- Alcoholism and Thiamine Deficiency
- Aldose Reductase and Taurine
- Diet, Metabolism, and Disease
- Metabolism and Genetic Disorders
- Fungal Infections and Studies
- Long-Term Effects of COVID-19
- Pulmonary Hypertension Research and Treatments
- Immune Cell Function and Interaction
- Biochemical Acid Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pain Mechanisms and Treatments
- Mitochondrial Function and Pathology
- Birth, Development, and Health
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nitric Oxide and Endothelin Effects
- DNA Repair Mechanisms
- Tryptophan and brain disorders
- Herbal Medicine Research Studies
- Congenital heart defects research
- Peptidase Inhibition and Analysis
- Cardiac Health and Mental Health
- Extracellular vesicles in disease
Instituto Nacional de Enfermedades Respiratorias
2012-2024
Background: Infection by SARS-CoV-2 has been associated with multiple symptoms; however, still, little is known about persistent symptoms and their probable association the risk of developing pulmonary fibrosis in patients post-COVID-19. Methods: A longitudinal prospective study on health workers infected was conducted. In this work, signs were recorded 149 a positive PCR test for at beginning diagnosis, during active infection, post-COVID-19 follow-up. The McNemar chi-square used to compare...
Abstract Background A deficient synthesis of nitric oxide (NO) may play a role in the early endothelial dysfunction healthy humans with strong family history type 2 diabetes (DM2). In this study, we evaluate intracellular NO and expression eNOS transcripts human umbilical vein cells (HUVECs), exposed to high glucose concentrations, newborns (experimental) without (control) DM2. Methods HUVECs were incubated M‐199 culture media (containing 5 mmol/L physiological concentration) or...
A common finding in patients admitted to an Intensive Care Unit (ICU) is hyperglycemia without prior history of diabetes. This increase blood glucose considered a negative prognostic factor for the ICU. Hence, we performed retrospective cohort study at ICU National Institute Respiratory Diseases (INER) 7-month period; collected data about their concentration during stay We gathered available medical records 30 out 58 Among patients, 21 survived (70%) and 9 with community-acquired pneumonia...
Hypertensive disorders of pregnancy (HDP), which affect 8% to 15% pregnancies, are associated with nitric oxide dysfunction and hyperlipidemia, but their precise role in HDP remains controversial. In order gain more insight into the mechanisms underlying HDP, we evaluated some indicators common diseases endothelial dysfunction.Plasma samples were obtained from 47 normotensive women (control group) 27 (experimental group). All 7 months pregnant. Body mass index as well triglycerides, nitrite...
The aim of this work was to determine the presence galectin-10 in nasal lavage fluid (NLF) patients with aspirin-sensitive respiratory disease (ASRD) before and after challenge L-ASA (aspirin) by ELISA. Fifteen ASRD patients, ten aspirin-tolerant asthmatics (ATA), fifteen healthy controls (HC) were studied. baseline Galectin-10 PBMC determined using real time PCR. evaluated tissue polyps western blot. Our results showed a lower expression than ATA controls. However, higher concentration NLF...
Abstract Background A family history of type 2 diabetes mellitus (DM) increases the probability to develop DM and endothelial dysfunction. The probable mechanism involves augmented reactive oxygen species (ROS) synthesis. aim this study was evaluate synthesis ROS in human umbilical vein cells (HUVECs) obtained from healthy newborns with (experimental) without (control) a strong DM, exposed different glucose concentrations. Methods HUVECs were various concentrations for 24 48 h periods,...