A5012687422- Advanced Radiotherapy Techniques
- Pulsars and Gravitational Waves Research
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Advanced X-ray and CT Imaging
- Geophysics and Gravity Measurements
- Gamma-ray bursts and supernovae
- Atomic and Subatomic Physics Research
- Hemoglobinopathies and Related Disorders
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Advanced Frequency and Time Standards
- Cosmology and Gravitation Theories
- Software Engineering Techniques and Practices
- Conflict Management and Negotiation
- Mechanical and Optical Resonators
- Prostate Cancer Diagnosis and Treatment
- Optical Imaging and Spectroscopy Techniques
- Iron Metabolism and Disorders
- PARP inhibition in cancer therapy
- Ethics in Business and Education
- Seismic Waves and Analysis
- Statistical and numerical algorithms
Carnegie Mellon University
2024
Surrey Memorial Hospital
2021
Bristol-Myers Squibb (United States)
2020
Vanderbilt University Medical Center
2019
Novartis (United States)
2016
BC Cancer Agency
2011-2016
National Tsing Hua University
2013-2015
Teamwork is a key learning outcome for our course, Foundations of Software Engineering. However, conflicts are inevitable in teams, and if students cannot resolve conflicts, this can lead to decreased satisfaction everyone on the team. In experience report, we present approach help deal with that occur team projects. Working faculty from School Business, following best practices organizational behaviour research, instructed how provide high quality peer feedback, designed activities where...
Background: Pts with anaplastic lymphoma kinase (ALK)-rearranged NSCLC have benefited from ALK tyrosine inhibitors (TKIs); however, most pts eventually acquire resistance. Identification of resistance mutations informs subsequent therapy but has typically required invasive repeat biopsies. Here, we assessed the utility ctDNA analysis and ability to monitor response longitudinally detect during ensartinib, a potent second-generation TKI. Methods: Blood samples were collected at start...
Purpose: A simple jaw calibration method is proposed for Varian TrueBeam using an EPID‐Encoder combination that gives accurate fields sizes and a homogeneous junction dose. This benefits clinical applications such as mono‐isocentric half‐beam block breast cancer or head neck treatment with junction/field matching. Methods: We use EPID imager pixel size 0.392 mm × to determine the radiation position measured from radio‐opaque markers aligned crosshair. acquire two images different symmetric...
Purpose: When a patient's anatomy spans beyond the scan field of view (sFOV) in CT scanner, extrapolation techniques are applied to reconstruct data extended (eFOV). However, it's challenging delineate external body contour accurately due image distortions within eFOV. Our proposed solution is apply TargetTape, disposable radio-opaque adhesive strip, patients. study investigates accuracy geometric reconstruction and dosimetric impact when using TargetTape Methods: With GE Optima CT,...
Purpose: Accurate jaw calibration is possible, but it does not necessarily achieve good junctions because of collimator rotation walkout. We developed a mathematical model seeking to pick an origin for that minimizes the walkout effect. Methods: use radioopaque markers aligned with crosshair on EPID determine at angles 0°, 90° and 270°. can accurately calibrate jaws any arbitrary near radiation field centre. While absolute position moves walkout, its relative location invariant. studied two...
During a VMAT treatment delivery, the interplay effect between moving target and varying machine parameters result in dose distributions that are different from those initially planned. In this work, we investigate for lung SABR by using 4D calculation derived Varian TrueBeam trajectory log file. The impact of start phase is also evaluated. A QUASAR™ respiratory motion phantom was scanned with amplitudes 0.4, 1, 2 3 cm 4 second period. MIP average dataset were generated 4DCT. static CT...
The interplay effect between the tumor motion and radiation beam modulation during a VMAT treatment delivery alters delivered dose distribution from planned one. This work present validate method to accurately calculate in 4D taking into account motion, field starting phase. A QUASAR™ respiratory phantom was scanned with amplitude of 3 cm second period. static scan also acquired lung insert contained it centered. plan 6XFFF created on averaged CT Varian TrueBeam trajectory log file saved....
Purpose: Metal artifact reduction (MAR) software in computed tomography (CT) was previously evaluated with phantoms demonstrating the algorithm is capable of reducing metal artifacts without affecting overall image quality. The goal this study to determine dosimetric impact when calculating CT datasets reconstructed and MAR software. Methods: Twelve head neck cancer patients dental fillings four pelvic hip prosthesis were scanned a GE Optima RT 580 scanner. Images 6MV IMRT VMAT plans...
Purpose: A new commercially available metal artifact reduction (MAR) software in computed tomography (CT) imaging was evaluated with phantoms the presence of metals. The goal to assess ability restore CT number vicinity metals without impacting image quality. Methods: Catphan 504 scanned a GE Optima RT 580 scanner (GE Healthcare, Milwaukee, WI) and images were reconstructed MAR software. Both datasets analyzed Image Owl QA (Image Inc, Greenwich, NY). sensitometry, MTF, low contrast,...
Purpose: In this abstract we implement and validate a 4D VMAT Acuros XB dose calculation using Gafchromic film. Special attention is paid to the physical material assignment in CT dataset reported water medium. Methods: A QUASAR phantom with 3 cm sinusoidal tumor motion 5 second period was scanned computed tomography. also obtained of static at central position. plan created on average delivered Varian TrueBeam linear accelerator. The trajectory log file from treatment acquired used create...
Dose verification as part of plan checking is a critical component high quality patient care. IMSure QA software platform used at the BC Cancer Agency that facilitates dose for both conformal and IMRT plans. We have recently initiated treating breast tangents using Fraser Valley Centre noted increased discrepancies (mean difference -3%) between Eclipse IMSure's module. identified two potential sources error: air flash tissue heterogeneity. extend our generated fluences 3cm past contour into...