A5025564062- Management of metastatic bone disease
- Brain Metastases and Treatment
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Palliative Care and End-of-Life Issues
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Radiopharmaceutical Chemistry and Applications
- Advances in Oncology and Radiotherapy
- Childhood Cancer Survivors' Quality of Life
- Medical Imaging Techniques and Applications
- Patient-Provider Communication in Healthcare
- Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Spine and Intervertebral Disc Pathology
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Screening and Detection
- Head and Neck Cancer Studies
- Prostate Cancer Treatment and Research
- Interprofessional Education and Collaboration
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- Ocular Oncology and Treatments
University of British Columbia
2012-2024
BC Cancer Agency
2013-2024
University of Calgary
2020
Cancer Council SA
2020
Southwestern Illinois College
2018
Spinal Cord Injury BC
2018
Vancouver Clinic
2017
Cancer Institute (WIA)
2013
University of Alberta
2006-2010
Optimal treatment of rectal cancer (RC) requires multidisciplinary care. We examined whether distance to center or community size impacts access multimodality care and population-based outcomes in RC.Patients diagnosed with stage II/III RC from 1999 2009 treated at 1 6 regional centers British Columbia were reviewed. Distance was determined for each patient. Communities classified as rural, small, medium, large population centers. Logistic Cox regression models assessed associations received...
Mutational analysis of c-KIT or PDGFRA has become an important laboratory assay for patients with gastrointestinal stromal tumors (GISTs) because the results are useful in predicting responsiveness to imatinib. To assess diagnostic usefulness denaturing high-pressure liquid chromatography (DHPLC) this setting, we performed DHPLC and DNA sequencing study exons 9, 11, 13, 17 12 18 54 consecutive cases GIST collected from a single population. Most (40/54 [74%]) carried mutations, 7 (13%)...
PurposeWhole brain radiation therapy (WBRT) remains the standard of care for patients with multiple metastases, but more than half treated will develop intracranial progression. Because there is no clear consensus on optimal therapeutic approach, a prognostic index would be helpful to guide treatment options at We explored whether recursive partitioning analysis (RPA) score prior repeat WBRT predictive survival.Methods and materialsThis multi-institutional pooled included 2 or metastases...
Metastases to the eye or orbit as initial presentation of genitourinary malignancy are unusual and can be a diagnostic challenge.We report an 81-year-old man who presented with pain proptosis in that had been blind for 50 years.Radiologic investigations identified mass involving left globe orbit.Histology enucleation specimen was consistent metastatic poorly differentiated carcinoma suggestive prostate primary.With constellation obstructive urinary symptoms, abnormal digital rectal...
Abstract Background Bone metastases in the lower spine and pelvis are effectively palliated with radiotherapy (RT), though this can come side effects such as radiation induced nausea vomiting (RINV). We hypothesize that high rates of RINV occur part because widespread use inexpensive simple unplanned palliative (SUPR), over more complex resource intensive 3D conformal RT, volumetric modulated arc therapy (VMAT). Methods This is a randomized, multi-centre phase III trial SUPR versus VMAT....
Objectives The Serious Illness Conversation Guide (SICG) has emerged as a framework for conversations with patients serious illness diagnosis. This study reports on narratives generated from open-ended questions of novel assessment tool, the Conversation-Evaluation Exercise (SIC-Ex), to assess resident-led in oncology outpatient clinics. Design Qualitative using template analysis. Setting Three academic cancer centres Canada. Participants 7 resident physicians (trainees), clinics, 10...
Abstract Background Radiotherapy delivery regimens can vary between a single fraction (SF) and multiple fractions (MF) given daily for up to several weeks depending on the location of cancer or metastases. With limited evidence comparing fractionation oligometastases, there is support explore toxicity levels nearby organs at risk as primary outcome while using SF MF stereotactic ablative radiotherapy (SABR) well differences in patient-reported quality life experience. Methods This study will...