A5082915637- Genetic and phenotypic traits in livestock
- Animal Nutrition and Physiology
- Livestock and Poultry Management
- Genomics and Chromatin Dynamics
- Biochemical Analysis and Sensing Techniques
- Cellular transport and secretion
- Cancer-related molecular mechanisms research
- Genetic Mapping and Diversity in Plants and Animals
- Biotin and Related Studies
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Meat and Animal Product Quality
- RNA modifications and cancer
- Metabolomics and Mass Spectrometry Studies
- RNA Research and Splicing
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Antioxidant Activity and Oxidative Stress
- Ubiquitin and proteasome pathways
South China Agricultural University
2020-2024
Poultry Research Institute
2024
Ministry of Agriculture and Rural Affairs
2023
The Ras and Rab interactor 2 ( RIN2 ) gene, which encodes RAS interacting protein 2, can interact with GTP-bound Rab5 participate in early endocytosis. This study found a 61-bp insertion/deletion (indel) the intron region, 3 genotypes II , ID DD were observed. Genotype analysis of mutation sites was performed on 665 individuals from F population 8 chicken breeds. It that indel existed each breed yellow feathered chickens mainly genotype. Correlation growth carcass traits Xinghua White...
Lutein can increase the body's skin color and has antioxidant potential. However, how it affects lipid metabolism oxidative stress in chickens remains unknown. In this study, 74-day-old male raised on feed supplemented with lutein had higher hip, back, breast, leg, shin abdominal fat yellowness than control group, livers of group superoxide dismutase glutathione peroxidase lower malondialdehyde activities. To clarify potential regulatory network regulated by lutein, we used RNA-seq...
Abstract Background G-protein subunit beta 1 like ( GNB1L ) encodes a beta-subunit-like polypeptide. Chicken is upregulated in the breast muscle of high feed efficiency chickens, and its expression 1.52-fold that low chickens. However, no report has described effects indels on chicken carcass growth traits. Results This study identified 31-bp indel 5′ untranslated region (UTR) elucidated effect this gene mutation traits The showed highly significant association with body weight at 8...
The yellow color of the skin is an important economic trait for chickens. Low and non-uniform yellowness would reduce efficiency. However, regulatory mechanism chicken has not been fully elucidated. In this study, we evaluated 819 chickens by colorimeter digital camera, which are from same batch age 2 pure lines with significant differences in yellowness. A total 982 candidate differential expressed genes (DEGs) were detected duodenal tissue RNA-seq analysis high low Among DEGs, chose fatty...
Molecular breeding accelerates animal and improves efficiency by utilizing genetic mutations. Structural variations (SVs), a significant source of mutations, have greater impact on phenotypic variation than SNPs. Understanding SV functional mechanisms obtaining precise information are crucial for molecular breeding. In this study, association analysis revealed correlations between 198-bp SVs in the GSTA2 promoter region abdominal fat weight, intramuscular content, subcutaneous thickness...
Lutein is an antioxidant that can indicate the oxidative status of organisms through its coloration and may be involved in development process chicken skeletal muscle. In this study, after feeding Nanhai Yellow Chickens with lutein-containing feed for 21 d, lutein group significantly increased muscle fiber diameter decreased density chicken's leg muscles compared to control group. To elucidate potential regulatory mechanisms by which development, RNA-seq was used detect changes gene...
Molecular breeding can accelerate the process of animal and improve efficiency. To date, many Indel molecular markers have been identified in livestock poultry, but how Indels affect economic traits is not well understood. For breeding, it crucial to reveal mechanism action provide more accurate information. The purpose this study was investigate 52/224-bp multiallelic chicken QPCTL promoter area daily weight gain chickens potential regulatory gene. analysis conducted by association...
Abstract Background : Ras and Rab interactor 2 ( RIN2 ) gene, encoding RAS interacting protein 2, can interact with GTP-bound Rab5 participate in early endocytosis. Deletion of may impair Rab5-related endosome signaling, leading to abnormal phenotypes. However, no research has been reported on the functions related animal production. Results: A 61-bp insertion/deletion (indel) intron region this study. The genotype analysis mutation sites was performed 550 individuals from 7 different...
Abstract Background: G-protein subunit beta 1 like ( GNB1L ) can encode a beta-subunit-like polypeptide, the chicken gene is up-regulated in breast muscle of high-feed efficiency chickens, and its expression 1.52-fold that low-feed chickens. However, there are no reports describing effects Indel on carcass growth traits. Results: This study identified 31-bp 5' UTR elucidated effect this mutation traits The results showed was highly significant associations with body weight at 8 different...
Abstract Background: G-protein subunit beta 1 like ( GNB1L ) encodes a beta-subunit-like polypeptide. Chicken is upregulated in the breast muscle of high feed efficiency chickens, and its expression 1.52-fold that low chickens. However, no report has described effects indels on chicken carcass growth traits. Results: This study identified 31-bp indel 5' untranslated region (UTR) elucidated effect this gene mutation traits The showed highly significant association with body weight at 8...
Abstract Background: G-protein subunit beta 1 like ( GNB1L ) encodes a beta-subunit-like polypeptide. Chicken is upregulated in the breast muscle of high feed efficiency chickens, and its expression 1.52-fold that low chickens. However, no report has described effects indels on chicken carcass growth traits.Results: This study identified 31-bp indel 5' untranslated region (UTR) elucidated effect this gene mutation traits The showed highly significant association with body weight at 8...
Abstract Background G-protein subunit beta 1 like ( GNB1L ) can encode a beta-subunit-like polypeptide, the chicken gene is up-regulated in breast muscle of high-feed efficiency chickens, and its expression 1.52-fold that low-feed chickens. However, there are no reports describing effects Indel on growth carcass traits Results This study identified 31-bp 5' UTR elucidated effect this mutation The results indicated was highly significant associations with body weight at 8 different stages,...