A5079927799- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Immune Cell Function and Interaction
- Bacterial Infections and Vaccines
- T-cell and B-cell Immunology
Children's Hospital Agia Sophia
2025
National and Kapodistrian University of Athens
2019-2024
Iaso Children’s Hospital
2019
Abstract Background Studies have analyzed the contribution of host and viral factors to RSV disease pathogenesis severity in children, but role RSV/viral co-detection is poorly understood. We investigated relationship between co-detection, loads, mucosal cytokine concentrations young children with acute respiratory infection (ARI). Methods enrolled a convenience sample previously healthy < 2 years age ARI that were either hospitalized or managed as outpatients at large pediatric...
Antigen-specific B cell identification by flow cytometry is crucial for investigating their immunophenotype, subset distribution, and kinetics post-infection or immunization. Methods using biotinylated polysaccharide antigens have been described, but there still room improvement regarding sensitivity applicability. The aim of this study was the development validation a multimer bead-based method detecting pneumococcal serotypes (PS)-specific cells following PS chemically mounted on...
Pneumococcal vaccination schedules are traditionally assessed based on the antibody response. The Memory B Cell (MBC) response has been less studied, despite its role in magnitude and longevity of protection. We compared immune to different with 13-valent Conjugate Vaccine (PCV13) investigated relationship between MBCs Total pneumococcal serotype (PS)-specific MBCs, their subsets PS-specific IgG antibodies induced by a 3 + 0 (group A), 2 1 B) or C) schedule healthy infants were studied...