A5017473942- Epigenetics and DNA Methylation
- Advanced Glycation End Products research
- Ovarian function and disorders
- Cancer-related gene regulation
- Glioma Diagnosis and Treatment
- Histone Deacetylase Inhibitors Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Alzheimer's disease research and treatments
- Cutaneous lymphoproliferative disorders research
- Genetic and Kidney Cyst Diseases
- Alcohol Consumption and Health Effects
- RNA modifications and cancer
- Microtubule and mitosis dynamics
- S100 Proteins and Annexins
- Parkinson's Disease Mechanisms and Treatments
- Chemokine receptors and signaling
- Mitochondrial Function and Pathology
- Phytoestrogen effects and research
- Cell Adhesion Molecules Research
- Cancer-related molecular mechanisms research
- Cardiovascular Health and Disease Prevention
- Lymphoma Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Tryptophan and brain disorders
- MicroRNA in disease regulation
National and Kapodistrian University of Athens
2016-2025
University of Minho
2018
Athens Medical Center
2015-2016
Athens State University
2013-2015
Creative Research Enterprises (United States)
2015
Merck & Co., Inc., Rahway, NJ, USA (United States)
2012
University of Naples Federico II
2009
Athens University of Economics and Business
2007
Biomedical Research Foundation of the Academy of Athens
2003
University of Oxford
1997-2002
Women with polycystic ovary syndrome (PCOS) have an increased prevalence of insulin resistance (IR) and related disorders. Elevated serum levels cellular adhesion molecules (CAMs) reflect low-grade chronic inflammation been associated several insulin-resistant states. The objective this study is to investigate whether soluble inflammatory markers [soluble intercellular molecule-1 (sICAM-1), endothelial leukocyte (sE-selectin), vascular cell (sVCAM-1) C-reactive protein (CRP)] are altered in...
The aim of this study was to investigate the endothelial status in young women with polycystic ovary syndrome (PCOS), using a simple and easily reproducible hemodynamic method combined biological marker evaluate effect metformin treatment on these parameters.Descriptive clinical trial.Forty women, 20 PCOS normal similar age body mass index were studied. Metformin (1700 mg daily) administered for 6 months group. endothelium metabolic hormonal profile studied both groups, as well after...
Nonenzymatic advanced glycation and oxidation end-products, end-products (AGEs), impart a potent impact on vessels other tissues in diabetic state euglycaemic conditions with increased oxidative stress. Insulin resistant (IR) polycystic ovary syndrome (PCOS) women, have elevated serum AGEs, receptor (RAGE) expression, deposition differential localization the ovarian tissue (theca granulosa) compared to normal.To determine whether raised AGE levels noninsulin women PCOS is distinct finding...
Abstract Background Women with polycystic ovary syndrome (PCOS) carry a pattern of cardiovascular risk factors. Endothelial dysfunction and chronic inflammation are early findings in the atherosclerotic process. The purpose study was to investigate coexistence active markers endothelial young women PCOS, their relationship metabolic hormonal abnormalities syndrome. Materials methods Twenty‐five PCOS 25 controls similar age body mass index (BMI) were studied. function assessed by...
Glycyrrhizin (glycyrrhizic acid), a bioactive triterpenoid saponin constituent of Glycyrrhiza glabra, is traditional medicine possessing plethora pharmacological anti-inflammatory, antioxidant, antimicrobial, and antiaging properties. It known inhibitor high mobility group box 1 (HMGB1), ubiquitous protein with proinflammatory cytokine-like activity. HMGB1 has been implicated in an array inflammatory diseases when released extracellularly, mainly by activating intracellular signaling upon...