A5013418490- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- MicroRNA in disease regulation
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Neurological Disease Mechanisms and Treatments
- Medical Imaging and Analysis
- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Bipolar Disorder and Treatment
- Cell Image Analysis Techniques
- Pain Mechanisms and Treatments
- Circadian rhythm and melatonin
- Endoplasmic Reticulum Stress and Disease
- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury Research
- Memory and Neural Mechanisms
- Neurological disorders and treatments
- Anesthesia and Neurotoxicity Research
- Pain Management and Treatment
- Heart Rate Variability and Autonomic Control
- Advanced MRI Techniques and Applications
- Attention Deficit Hyperactivity Disorder
- Neurological Disorders and Treatments
Ewha Womans University
2017-2023
Val66Met, a naturally occurring polymorphism in the human brain-derived neurotrophic factor (BDNF) gene resulting valine (Val) to methionine (Met) substitution at codon 66, plays an important role neuroplasticity. While effect of BDNF Val66Met on local brain structures has previously been examined, its impact configuration graph-based white matter structural networks is yet be investigated. In current study, we assessed network properties and robustness networks. Graph theory was employed...
The degree and salience of pain have been known to be constantly monitored modulated by the brain. In case maladaptive neural responses as reported in centralized conditions such complex regional syndrome (CRPS), perception is amplified remains elevated even without sustained peripheral inputs. Given that attentional state brain greatly influences interpretation pain, we investigated role attention network its dynamic interactions with other pain-related networks CRPS. We examined...
Abstract Brain network is organized to maximize the efficiency of both segregated and integrated information processing that may be related human intelligence. However, there have been surprisingly few studies focus on topological characteristics brain underlying extremely high intelligence intellectual giftedness, particularly in adolescents. Here, we examined topology 25 adolescents with superior (SI-Adol), average (AI-Adol), 27 young adults AI (AI-Adult). We found SI-Adol had properties...
Abstract The epigenetic regulation of microRNA (miRNA) expression related to the FK506-binding protein 5 (FKBP5) gene may contribute risk stress-related disorders such as posttraumatic stress disorder (PTSD). Here, we identified candidate miRNAs derived from FKBP5 knockout mice a potential diagnostic biomarker PTSD. Using translational approach, found alter in within medial prefrontal cortex were selected. Each miRNA was examined serum 48 recently traumatized individuals with PTSD and 47...
Polygonatum sibiricum (PS) rhizome, which contains glyceryl-1-monolinoleate as its primary active component, has been shown to improve insomnia in animal models. Based on these findings, we aimed investigate the safety and efficacy of PS rhizome extract improving sleep quality individuals with mild insomnia. Eighty were enrolled a four-week, randomized, double-blind, placebo-controlled trial (500 mg/day, n = 40, group) or placebo (n group). The outcome measure was change total score Athens...
Growing evidence indicates that type 2 diabetes mellitus (T2DM)-related cognitive dysfunction may develop in the early stage of disease and is often accompanied by hippocampal structural alterations. In current study, we investigated volume shape alterations hippocampus at a subregional level patients with T2DM. Using high-resolution brain images were obtained from 30 T2DM less than 5 years duration, healthy individuals, volumetric analyses performed. We also assessed relationship between...
The propensity to engage in risky behaviors including excessive alcohol consumption may impose increased medical, emotional, and psychosocial burden. Personality behavioral traits of individuals contribute part the involvement behaviors, therefore classification one's help identify those who are at risk for future onset addictive disorder related issues such as misuse. characteristics impulsivity, anger, reward sensitivity, avoidance were assessed a large sample healthy young adults (n =...